Hypothyroidism News and Research

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Hypothyroidism occurs when the thyroid gland does not produce enough thyroid hormone to meet the body’s needs. Without enough thyroid hormone, many of the body’s functions slow down. About 5 percent of the U.S. population has hypothyroidism. Women are much more likely than men to develop hypothyroidism.

Hypothyroidism linked to higher risk of obstructive sleep apnea

According to a study conducted in Brazil by researchers at the Federal University of São Paulo (UNIFESP) with participants from the São Paulo Epidemiological Sleep Study (EPISONO 2018), people with hypothyroidism experience a higher frequency and severity of obstructive sleep apnea (OSA).

5 Aug 2026

Too little or too much iodine may push immunity off balance

This narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.

27 Jul 2026

High physician knowledge scores linked to lower healthcare costs

Patients whose physicians scored higher in the first year of the American Board of Internal Medicine's (ABIM) Internal Medicine Longitudinal Knowledge Assessment (LKA) were significantly less likely to receive low-value healthcare services, which cumulatively cost the U.S. healthcare system an estimated $100 billion each year.

13 Jul 2026

WHO urges countries to expand newborn screening for birth defects

The World Health Organization (WHO) today calls on countries to expand newborn screening for birth defects, highlighting how early detection and treatment can save lives and reduce lifelong disability for millions of children.

24 Jun 2026

GLP-1 therapies linked to fewer complications in adults with both obesity and autoimmune disease

Among adults with both obesity and an autoimmune disease, those taking a glucagon-like peptide-receptor 1 agonist (GLP-1RA) medication had lower rates of emergency department visits and were less likely to experience serious cardiac events, such as stroke, pulmonary embolism or death when compared to similar adults who were not taking these medications, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

7 Jun 2026

Wearable devices may help detect menstrual health changes earlier

Digital health tools, including wearables, provide critical data on menstrual health, enhancing understanding of hormonal fluctuations and women's well-being.

27 May 2026

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Early and accurate prognostic assessment is crucial to prevent disease progression in liver failure. Thyroid hormones (THs), particularly triiodothyronine (T3), are key metabolic regulators and play an important role in liver regeneration. Liver failure is frequently complicated by non‑thyroidal illness syndrome (NTIS), characterized by low T3 with normal or slightly elevated TSH and T4.

14 May 2026

Study identifies key risk factors driving MASLD across populations

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 32% of the US adult population.

23 Apr 2026

Can diet influence thyroid disease? A major review points to Mediterranean-style eating

This review found that thyroid health depends on more than iodine alone, with selenium, iron, zinc, vitamins, omega-3s, and overall eating patterns all shaping thyroid function and autoimmunity. It also concluded that Mediterranean-style diets are linked to more favorable thyroid outcomes, while unnecessary restrictive diets offer little benefit without a clear medical indication.

7 Apr 2026

Blood-based test could personalize treatment for patients with HPV-associated throat cancer

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer.

2 Apr 2026

Genomic sequencing may expand newborn screening beyond biochemical tests

Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the range of conditions that can be identified at birth. Next-generation sequencing is being explored as a complementary screening tool.

16 Mar 2026

Nearly 70 weeks after infection, long COVID patients show no detectable inflammation in blood tests

A controlled Norwegian case-control study examined circulating biomarkers of inflammation and neuronal injury in people with long COVID about 69 weeks after infection. The researchers found no significant differences in systemic inflammatory or neuroinjury markers compared with recovered controls after statistical correction.

4 Mar 2026

New report highlights a rare case of 5-fluorouracil-induced hyperammonemic encephalopathy

A new case report was published in Volume 12 of Oncoscience on December 23, 2025, titled "Silent toxicity: A rare case of 5-fluorouracil-induced hyperammonemic encephalopathy."

5 Feb 2026

Next-generation sequencing expands possibilities for newborn screening

Every year, millions of newborns undergo routine screening as a preventive strategy to detect inherited disorders before symptoms emerge.

4 Feb 2026

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

How genomic screening in newborns found 16 hidden disorders standard tests overlooked

Genomic newborn screening using whole-genome sequencing identified 1.6% of infants with high-chance, treatable genetic conditions, far beyond the capacity of standard biochemical screening. The BabyScreen+ study demonstrated clinical impact, cascade diagnoses, and strong parental acceptance, while highlighting challenges in scalability and equity.

13 Oct 2025

Menopause found to shape initial symptoms and comorbidities in multiple sclerosis

New research presented today at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS 2025) reveals that menopause may significantly influence how multiple sclerosis (MS) first presents in women, as well as the types of associated health conditions they experience.

24 Sep 2025

Underactive thyroid linked to increased risk of small intestinal bacterial overgrowth

People with an underactive thyroid may have an increased risk of developing small intestinal bacterial overgrowth (SIBO), a risk that may be reduced with thyroid hormone treatment, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Iodine fortification urged as plant-based milk rise in popularity

Iodine content in plant-based milks is often insufficient, risking deficiencies that affect metabolism and public health, especially in reproductive-age women.

20 Jun 2025

Higher BMI, not menopause age, increases hypothyroidism risk

Researchers analyzed over 15,000 postmenopausal Canadian women to investigate whether age at natural menopause influences the risk of developing overt hypothyroidism. The study found no association, but higher BMI was linked to increased hypothyroidism risk.

29 May 2025