Mitral Regurgitation News and Research

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New low-cost artificial mitral valve mimics human tissue to study disease

Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart.

11 Jun 2026

M-TEER procedure effectively treats mitral regurgitation in patients with calcification

Results from a new analysis show that patients with mitral annular calcification (MAC) who undergo minimally invasive mitral transcatheter edge-to-edge repair (M-TEER) experience similar reductions in mitral regurgitation (MR) and improvement in quality of life compared to those seen in patients without calcification.

24 Apr 2026

Transcatheter valve replacement helps patients with limited heart care options

Findings from the AltaValve™ Early Feasibility Study suggest that patients with a leaky mitral valve have sustained clinical benefits one year following atrial fixation Transcatheter Mitral Valve Replacement (TMVR).

23 Apr 2026

AI-powered stethoscopes enable early detection of heart valve disease

Artificial intelligence could help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives, a new study suggests.

10 Feb 2026

Interventions to treat valvular heart disease in cancer patients significantly improve survival

Valvular heart disease, identified through cardiovascular imaging, is common in cancer patients. Interventions to treat valvular heart disease significantly improved survival.

11 Dec 2025

Clinically significant valvular heart disease vastly underdiagnosed in U.S. elders

Results from the PREVUE-VALVE study suggest that there are currently at least 4.7 million people aged 65-85 living with moderate or greater valvular heart disease (VHD) in the United States, and at least 10.6 million with clinically significant VHD, most of whom are unaware of their condition.

28 Oct 2025

Updated guidelines aim to standardize valvular heart disease care across Europe

Updated ESC/EACTS Guidelines, being published today at ESC Congress 2025, aim to improve the way that patients with valvular heart disease are diagnosed and treated, responding to robust new evidence that suggests some newer and less invasive treatments could be offered more widely and consistently to patients.

30 Aug 2025

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully-causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR).

6 Aug 2025

Heart failure and atrial fibrillation at the time of mitral valve repair linked to worse outcomes

Patients with heart failure and atrial fibrillation (AF) at the time of mitral transcatheter edge-to-edge repair (M-TEER) for severe mitral regurgitation are more than twice as likely to die or be rehospitalized for heart failure, compared to patients without AF.

18 Jul 2025

Study explores impact of severe tricuspid regurgitation in AFMR patients

Atrial functional mitral regurgitation (AFMR) is a common type of MR linked to high rates of heart failure, highlighting the need to understand its prognostic factors.

14 Mar 2025

AI program enhances echocardiogram interpretation and reduces wait times

Using an artificial intelligence program to read echocardiograms may reduce the wait time for results and help lead to more timely medical care, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Study challenges early intervention for asymptomatic aortic stenosis

The EVOLVED trial found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis (AS) and mid-wall myocardial fibrosis on magnetic resonance imaging did not reduce the incidence of the composite primary endpoint of all-cause death or unplanned aortic stenosis hospitalization compared with guideline-directed conservative management.

30 Oct 2024

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to severe functional mitral regurgitation (FMR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

There was no difference in efficacy between transcatheter edge-to-edge repair (TEER) and surgery in patients with secondary mitral regurgitation (MR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

In 2016, medical device giant Abbott issued a recall for its MitraClip cardiac device — "a Class I recall, the most serious type," the FDA said.

15 Aug 2024

Stratifying TAVI candidates with degenerative MR: Prognostic considerations

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transcatheter aortic valve implantation (TAVI) has emerged as the primary treatment strategy for severe symptomatic aortic stenosis (AS) in the older population (>75 years of age) with high-risk surgical profiles.

18 Jul 2024