Cell Biology

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Researchers unravel cellular mechanisms driving the initiation of mammary gland development

Helsinki University research group used live tissue imaging for the first time to visualize the emergence of the mammary gland.

21 Jun 2021

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Researchers from the German Center for Infection Research at Charité - Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage.

21 Jun 2021

New technique can measure metabolic process at the single-cell level

Understanding cellular metabolism - how a cell uses energy- could be key to treating a wide array of diseases, including vascular diseases and cancer.

18 Jun 2021

Yeast cell machinery seamlessly 'reads' the unnatural ingredients in the genetic recipe

If the genome is the recipe of life, base pairs are the individual ingredients listed. These chemical structures form DNA, and every living organism on Earth has just four. The specific arrangements of these four base pairs -- A, T, C, G -- make us who and what we are.

18 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Novel peptide-based hydrogels hold great promise for tissue engineering applications

Tissue-engineering scaffolds built around ultrashort peptides provide a new platform for studying bone regeneration in the lab.

17 Jun 2021

Scientists decipher the activation mechanism of a chemokine receptor

Chemokine receptors, located at the surface of many immune cells, play an important role in their function. Chemokines are small proteins that bind to these receptors and control the movement and behavior of white blood cells.

16 Jun 2021

Researchers identify properties that enable proteins to remember and respond to pressure

A new rubber band stretches, but then snaps back into its original shape and size. Stretched again, it does the same. But what if the rubber band was made of a material that remembered how it had been stretched? Just as our bones strengthen in response to impact, medical implants or prosthetics composed of such a material could adjust to environmental pressures such as those encountered in strenuous exercise.

16 Jun 2021

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Getting energy and nutrients from the environment - that is, eating - is such an important function that it has been regulated through sophisticated mechanisms over hundreds of millions of years. Some of these mechanisms are only now beginning to be unraveled.

16 Jun 2021

Researchers explore potential exposure to microbial agents in-utero

The human fetal immune system begins to develop early during gestation, however, factors responsible for fetal immune-priming remain elusive.

16 Jun 2021

Using natural killers from the immune system to target breast cancer cells

It sounds like a plot from a Quentin Tarantino movie -- something sets off natural killers and sends them on a killing spree.

16 Jun 2021

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

\A team of SMU biological scientists has confirmed that P-glycoprotein (P-gp) has the ability to remove a toxin from the brain that is associated with Alzheimer's disease.

16 Jun 2021

Precise manipulation of folate metabolism may pave way to broadly improve health during aging

Several different causes of aging have been discovered, but the question remains whether there are common underlying mechanisms that determine ageing and lifespan.

16 Jun 2021

Researchers report on the role of brain cell membranes' lipids in Alzheimer's progression

Alzheimer's disease is predominant in elderly people, but the way age-related changes to lipid composition affect the regulation of biological processes is still not well understood.

15 Jun 2021

New AI model could help predict which viruses are likely to spread from animals to humans

A new model that applies artificial intelligence to carbohydrates improves the understanding of the infection process and could help predict which viruses are likely to spread from animals to humans.

15 Jun 2021

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage is to prevent the two DNA strands from separating so that the cellular machinery cannot read the instructions written in the genes.

15 Jun 2021

Differential localization may explain different physiological functions of receptors

In the heart there are two different subtypes of beta-adrenergic receptors - beta1 and beta2 - which are activated by the stress hormones adrenaline and noradrenaline.

15 Jun 2021

Molecular biologists elucidate the key role of motor proteins in cell division

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase.

15 Jun 2021

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Researchers have succeeded for the first time in demonstrating the role of hypothalamic astrocytes in obesity-related hypertension.

15 Jun 2021

Cancer cells use an aging gene to establish permanent footing

Researchers at the University of Helsinki and the Beatson Institute for Cancer Research in Glasgow have discovered how mutated cells promote their chances to form cancer. Typically, the accumulation of harmful cells is prevented by active competition between multiple stem cells in intestinal glands, called crypts.

15 Jun 2021

Cell Biology

Researchers unravel cellular mechanisms driving the initiation of mammary gland development

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

New technique can measure metabolic process at the single-cell level

Yeast cell machinery seamlessly 'reads' the unnatural ingredients in the genetic recipe

Study: Cancer cells grown in culture dishes have less parity with their human sources

Novel peptide-based hydrogels hold great promise for tissue engineering applications

Scientists decipher the activation mechanism of a chemokine receptor

Researchers identify properties that enable proteins to remember and respond to pressure

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Researchers explore potential exposure to microbial agents in-utero

Using natural killers from the immune system to target breast cancer cells

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

Precise manipulation of folate metabolism may pave way to broadly improve health during aging

Researchers report on the role of brain cell membranes' lipids in Alzheimer's progression

New AI model could help predict which viruses are likely to spread from animals to humans

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Differential localization may explain different physiological functions of receptors

Molecular biologists elucidate the key role of motor proteins in cell division

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Cancer cells use an aging gene to establish permanent footing

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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