Cell Biology

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New stem cell therapy shows promise to prevent diabetes-related amputations

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

7 Apr 2021

Mouse model provides new understanding about Folling Disease

In Norway, all newborn children are tested for 25 rare genetic diseases through the Newborn Screening program, and the most common of these is phenylketonuria (abbreviated to PKU), known as Folling Disease.

7 Apr 2021

Finding ways to reverse a genetic cause of poor stress responses in mice

Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well as others.

7 Apr 2021

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analyzed the whole genomes of tumor samples from over 2,600 patients with different types of cancer.

7 Apr 2021

Gut microbiome communicates with horse’s cells to enhance their athletic performance

A horse’s gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its energy output, finds a new study published in Frontiers in Molecular Biosciences.

7 Apr 2021

Study reveals sex-differences in aging of the brain stem cell niche

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis.

7 Apr 2021

Scientists develop new method that advances single-cell transcriptomic technologies

Scientists at Oxford Brookes University have developed a new single-cell transcriptomic method which will aid multiple fields of biology, including the study of human health, disease and injury.

7 Apr 2021

Canopy Biosciences introduces high-plex spatial biology assay for quantitative immune cell profiling

Canopy Biosciences, a Bruker Company, today announced the launch of its Spatial Immune Cell Profiling Assay for formalin-fixed paraffin-embedded (FFPE) tissue samples.

From Bruker Nano Surfaces and Metrology 7 Apr 2021

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

7 Apr 2021

Tissue architecture impacts the evolutionary course of cancer

Tumors are genetically diverse with different mutations arising at different times throughout growth and development.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

Researchers generate a precise map of basal ganglia connectivity

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.

5 Apr 2021

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor (TCR) sequencing data. T-cell receptors are found on the surface of immune T cells.

5 Apr 2021

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Researchers in Italy have identified a pair of microRNA molecules that help maintain a population of cancerous stem cells that drive the growth of breast cancers and initiate tumor relapse after treatment.

3 Apr 2021

Scientists use a novel two-step method to track receptor proteins

The neurons in our nervous system "talk" to each other by sending and receiving chemical messages called neurotransmitters.

3 Apr 2021

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has long studied neglected tropical diseases -- chronic and disabling parasitic infections that primarily affect poor and underserved communities in developing nations.

3 Apr 2021

Study shows developmental trajectory of gut microbiota in cesarean-born babies

Infants born by cesarean section have a relatively meager array of bacteria in the gut. But by the age of three to five years they are broadly in line with their peers. This is shown by a study that also shows that it takes a remarkably long time for the mature intestinal microbiota to get established.

1 Apr 2021

Cell Biology

New stem cell therapy shows promise to prevent diabetes-related amputations

Mouse model provides new understanding about Folling Disease

Finding ways to reverse a genetic cause of poor stress responses in mice

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Gut microbiome communicates with horse’s cells to enhance their athletic performance

Study reveals sex-differences in aging of the brain stem cell niche

Scientists develop new method that advances single-cell transcriptomic technologies

Canopy Biosciences introduces high-plex spatial biology assay for quantitative immune cell profiling

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

Tissue architecture impacts the evolutionary course of cancer

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

Researchers generate a precise map of basal ganglia connectivity

New RNA-sequencing method can help detect numerous modified small RNAs

High expression of cell death genes may increase risk of early death from lung cancer

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Scientists use a novel two-step method to track receptor proteins

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

Study shows developmental trajectory of gut microbiota in cesarean-born babies

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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