Cell Biology

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Researchers map the first complete atlas of single cells that make up the human teeth

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.

27 Apr 2021

Drug cocktail can effectively activate and expand muscle stem cells

Skeletal muscle – the type of muscle that attaches to bones and enables movement – is the most abundant tissue in the human body.

27 Apr 2021

Researchers discover elusive cell type in fish sensory organs

One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells.

26 Apr 2021

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

26 Apr 2021

AI platform can identify specific proteins that allow bacteria to infect the intestines

Researchers from Tel Aviv University have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines - a method that paves the way for the creation of smart drugs that will neutralize the proteins and prevent disease, without the use of antibiotics.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

There are many different types of cancer, but they all have one thing in common: errors in the signals that control normal cell behavior can cause uncontrolled cell growth and cell division, leading to a tumor.

23 Apr 2021

Researchers develop computer model to predict the impact of individual receptors on brain activity

Researchers regard the overall distribution of receptors in the brain – the receptome – as a new approach for computer models that reproduce the function of the brain, and for diagnostics and therapy of mental disorders.

23 Apr 2021

New platform helps non-experts use AI to analyze microscopy images

A new, freely available platform helps non-experts use artificial intelligence to analyze microscopy images. The platform has been developed at Åbo Akademi University in Finland and Instituto Gulbenkian de Ciência, Portugal, and will be of big help in research and diagnostics using modern day microscopes.

23 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Recreating early embryos using stem cells

In their effort to understand the very earliest stages of life and how they can go wrong, scientists are confronted with ethical issues surrounding the use of human embryos.

23 Apr 2021

New imaging technique captures movies of receptors on the surface of living cells

A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children's Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.

23 Apr 2021

Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.

22 Apr 2021

Interleukin 11-producing fibroblasts can be potential therapeutic targets for treating colorectal cancer

IL-11 is known to promote the development of colorectal cancer in humans and mice, but when and where IL-11 is expressed during cancer development is unknown.

22 Apr 2021

New miniaturized model of neuromuscular junction formation provides insight into ALS

Skeletal muscles enable voluntary movements and are controlled by a special type of neurons called motor neurons, which make direct contact with skeletal muscles through so-called neuromuscular junctions (NMJs).

22 Apr 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection.

21 Apr 2021

Researchers discover how SARS viruses enhance the production of viral proteins in infected cells

Coronavirus researchers led by Professor Rolf Hilgenfeld of the University of Luebeck and PD Dr. Albrecht von Brunn of the Ludwig-Maximilian Universitaet in Munich have discovered how SARS viruses enhance the production of viral proteins in infected cells, so that many new copies of the virus can be generated.

21 Apr 2021

Study focuses on understanding the origin of neuronal diversity

A mechanistic understanding of brain development requires a systematic survey of neural progenitor cell types, their lineage specification and maturation of postmitotic neurons.

21 Apr 2021

Organ tissues become increasingly immune throughout life, new study suggests

University of Minnesota Medical School researchers have offered new ways to think about the immune system thanks to a recent study published in Nature.

20 Apr 2021

Cell Biology

Researchers map the first complete atlas of single cells that make up the human teeth

Drug cocktail can effectively activate and expand muscle stem cells

Researchers discover elusive cell type in fish sensory organs

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

AI platform can identify specific proteins that allow bacteria to infect the intestines

Researchers investigate how oxygen radicals protect against cancer

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

Researchers develop computer model to predict the impact of individual receptors on brain activity

New platform helps non-experts use AI to analyze microscopy images

Researchers create a cell library to study how various sugars bind to and interact with receptors

Recreating early embryos using stem cells

New imaging technique captures movies of receptors on the surface of living cells

Researchers discover molecule that provides dual protection against vascular inflammation

Interleukin 11-producing fibroblasts can be potential therapeutic targets for treating colorectal cancer

New miniaturized model of neuromuscular junction formation provides insight into ALS

Novel approach to gene editing bypasses disease-causing mutations in a gene

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Researchers discover how SARS viruses enhance the production of viral proteins in infected cells

Study focuses on understanding the origin of neuronal diversity

Organ tissues become increasingly immune throughout life, new study suggests

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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