Cell Biology

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RNA plays key role in helping stem cells know what to become

Look deep inside our cells, and you'll find that each has an identical genome -a complete set of genes that provides the instructions for our cells' form and function.

7 Jul 2020

Study of lysosomal function during mitosis reveals new biomarker for chromosomal instability

A team from the Bellvitge Biomedical Research Institute and the University of Barcelona, in collaboration with a researcher from the Mayo Clinic and the University of Minnesota, have described that lysosomes and autophagy processes are active during mitosis and are necessary for a correct cell division.

7 Jul 2020

Scientists engineer natural killer cells that target tumors and their immunosuppressive allies

Scientists have engineered natural killer immune cells that not only kill head and neck tumor cells in mice but also reduce the immune-suppressing myeloid cells that allow tumors to evade the immune response, according to a new study in eLife.

7 Jul 2020

New discovery helps explain heart defects in Barth syndrome

The heart needs energy to pump blood. So, energy production defects in heart muscles result in a variety of cardiac diseases.

7 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome.

6 Jul 2020

BU researchers develop new method to better understand cell communication

Researchers from Boston University School of Medicine have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

6 Jul 2020

Real-time tracking of protein filaments in the nuclear pore complex

In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing solution in the inside of a cell).

6 Jul 2020

New assay uses unique fluorescent tags to analyze multiple cell populations

An efficient, robust method of examining the interactions between cells uses fluorescent tagging to simultaneously analyze multiple cell populations, speeding up a once tedious and limiting process.

6 Jul 2020

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack.

6 Jul 2020

New strategies can help increase the efficiency of artificial cell reprogramming

Maria-Elena: Can you imagine being able to artificially generate cells that can develop into any cell type? That would be really fantastic! We call this ability 'totipotency' and it is the highest level of cellular plasticity.

6 Jul 2020

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress - a new study confirms.

3 Jul 2020

New formula more accurately compares the ages of humans and dogs

If there's one myth that has persisted through the years without much evidence, it's this: multiply your dog's age by seven to calculate how old they are in "human years." In other words, the old adage says, a four-year-old dog is similar in physiological age to a 28-year-old person.

2 Jul 2020

New platform helps investigate harmful effects of microplastics and nanoplastics

Plastic pollution is a critical environmental issue facing the world today, yet the impact of all the microplastics (MPs) and nanoplastics (NPs) that have seeped into the food and beverage supply on human health is an "undervalued avenue of research," according to the team behind a revealing new study released today in STEM CELLS.

2 Jul 2020

Studies show how individual cells maintain their internal clocks

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

Scientists find a simpler approach to generate sensory cells of the inner ear

Scientists from the USC Stem Cell laboratories of Neil Segil and Justin Ichida are whispering the secrets of a simpler way to generate the sensory cells of the inner ear.

1 Jul 2020

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

Cell Biology

RNA plays key role in helping stem cells know what to become

Study of lysosomal function during mitosis reveals new biomarker for chromosomal instability

Scientists engineer natural killer cells that target tumors and their immunosuppressive allies

New discovery helps explain heart defects in Barth syndrome

DNA resection pathways are highly specific, shows study

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

BU researchers develop new method to better understand cell communication

Real-time tracking of protein filaments in the nuclear pore complex

New assay uses unique fluorescent tags to analyze multiple cell populations

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New strategies can help increase the efficiency of artificial cell reprogramming

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

New formula more accurately compares the ages of humans and dogs

New platform helps investigate harmful effects of microplastics and nanoplastics

Studies show how individual cells maintain their internal clocks

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

Researchers discover a protein that protects B cells from stress-induced cell death

Scientists find a simpler approach to generate sensory cells of the inner ear

Research shows how a protein's small change leads to big trouble for cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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