Cell Biology

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Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say.

4 Mar 2021

New transcriptome‐based aging clock reads the biological age of an organism

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome.

3 Mar 2021

Researchers identify drug target to fight Parkinson’s and Alzheimer’s disease

Neurodegenerative disorders such as Parkinson's and Alzheimer's disease are in the firing line after researchers identified an attractive therapeutic drug target.

3 Mar 2021

Researchers develop shape memory polymer to understand the development of heart disease

Cardiovascular disease remains the number one cause of death globally. Unfortunately, the heart cannot regenerate new tissue, because the cardiomyocytes, or heart muscle cells, do not divide after birth.

3 Mar 2021

Study reveals how cells build 'mini-muscles' underneath their nucleus

Research groups at the University of Helsinki uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile structures at the inner face of the cell membrane.

2 Mar 2021

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Disruptions in the circadian rhythms in lung cells may explain why adults who survived premature birth are often more at risk of severe influenza infections, suggests a study in mice published today in eLife.

2 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs.

2 Mar 2021

Newly discovered protein regulates molecular motors in response to light

Single-celled algae and animal sperm cells are widely separated in evolution but both swim in the same way, by waving their protruding hairs, called cilia or flagella. Motion is driven by molecular motors, complex assemblies of proteins that exert a force when changing shape.

1 Mar 2021

Exposure to periods of low oxygen can result in underdeveloped jaw cartilage

Breathing in adequate amounts of oxygen is critical for human life. However, certain disorders can cause individuals to go through periods where they are exposed to periodical low levels of oxygen, called intermittent hypoxia (IH).

1 Mar 2021

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph Disease (MJD), describes the most common form of dominantly inherited ataxia in many populations worldwide, including Hong Kong and mainland China.

1 Mar 2021

New method boosts research efforts to eradicate cancer at its source

A new method, described in a study published today in the journal Nature Communications, has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

1 Mar 2021

Genomic Data Commons offers the largest resource in cancer genomics

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

27 Feb 2021

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central nervous system.

26 Feb 2021

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

26 Feb 2021

Cell Biology

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

New transcriptome‐based aging clock reads the biological age of an organism

Researchers identify drug target to fight Parkinson’s and Alzheimer’s disease

Researchers develop shape memory polymer to understand the development of heart disease

Study reveals how cells build 'mini-muscles' underneath their nucleus

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Yale researchers identify multiple genes involved in suppression of axon regeneration

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Newly discovered protein regulates molecular motors in response to light

Exposure to periods of low oxygen can result in underdeveloped jaw cartilage

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

New method boosts research efforts to eradicate cancer at its source

Genomic Data Commons offers the largest resource in cancer genomics

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

New 'E-Morph' test method replaces animal experiments to detect hormone-like effects

OHSU study represents a new milestone in the field of precision medicine

Proteins play crucial role in muscle growth

Study reveals molecular details of SARS-CoV-2 interactions with human cells

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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