Cell Biology

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Studies show how individual cells maintain their internal clocks

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

Scientists find a simpler approach to generate sensory cells of the inner ear

Scientists from the USC Stem Cell laboratories of Neil Segil and Justin Ichida are whispering the secrets of a simpler way to generate the sensory cells of the inner ear.

1 Jul 2020

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

Researchers track brain receptor as it transmits or inhibits neural signals

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain development and function, the receptor converts chemical messages between cells into electrical signals within a neuron.

30 Jun 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

New method for analyzing intact tumor samples to be used for studying COVID-19

Researchers at Karolinska Institutet in Sweden have developed a new method for analyzing intact tumor samples in 3D on a molecular level.

29 Jun 2020

Scientists discover osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Biophysicists propose a simple way to observe heart tissue

Biophysicists from the Moscow Institute of Physics and Technology and their colleagues have proposed a simple way to observe the heart tissue.

29 Jun 2020

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells.

29 Jun 2020

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

A research team lead by Ludmilla Morozova Roche at Umeå University, Sweden, has provided the mechanistic insight into protein co-aggregation in Alzheimer's disease.

26 Jun 2020

A novel strategy to achieve site-selective chiral drug synthesis in living systems

Enantioselectivity plays an important role in the pharmacological and toxicological processes of chiral drugs.

26 Jun 2020

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.

26 Jun 2020

Researchers identify new protein complex that regulates chromosome separation

Researchers from the University of Tsukuba have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division

26 Jun 2020

Researchers identify new molecules to study specific glial cells integral to synapses

While the brain is composed of two types of cells, glia tend to receive far less attention for their importance in brain function and disease than the more celebrated neurons.

26 Jun 2020

Researchers discover receptor that makes mice strong and slim

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects.

25 Jun 2020

Simplified artificial cell brings to light the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

25 Jun 2020

Study provides novel insights into how fat cells reduce lipid metabolism with age

Knowledge of how human fat tissue is affected by age has long been defined by numerous mouse-based studies.

25 Jun 2020

Cell Biology

Studies show how individual cells maintain their internal clocks

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

Researchers discover a protein that protects B cells from stress-induced cell death

Scientists find a simpler approach to generate sensory cells of the inner ear

Research shows how a protein's small change leads to big trouble for cells

Researchers track brain receptor as it transmits or inhibits neural signals

A data-rich atlas of the developing human brain

New method for analyzing intact tumor samples to be used for studying COVID-19

Scientists discover osmotic stress as stimulator of cellular waste disposal

Biophysicists propose a simple way to observe heart tissue

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

A novel strategy to achieve site-selective chiral drug synthesis in living systems

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers identify new protein complex that regulates chromosome separation

Researchers identify new molecules to study specific glial cells integral to synapses

Researchers discover receptor that makes mice strong and slim

Simplified artificial cell brings to light the dynamics of cellular symmetry

Study provides novel insights into how fat cells reduce lipid metabolism with age

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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