Cell Biology

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Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

Researchers find link between increased proteostasis and immortality of stem cells

Stem cells are considered to be immortal in culture and, therefore, of great interest for aging research. This immortality is regulated by increased proteostasis, which controls the quality of proteins.

8 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

Scientists link protein to seizure suppression

According to a new study, seizures can be suppressed in the brain by a protein called T-cell intracellular antigen-1 (TIA-1).

8 Mar 2018

Neurogenesis diminishes after childhood, finds study

In a recent study, scientists concluded that adult neurogenesis, which is seen in other species, does not occur in human beings.

8 Mar 2018

Salk researchers uncover power switch for muscles

If you've ever wondered how strenuous exercise translates into better endurance, researchers at the Salk Institute may have your answer. In a study published in the journal Cell Reports on March 6, 2018, scientists in Ronald Evans' lab have shown that the protein ERRγ (ERR gamma) helps deliver many of the benefits associated with endurance exercise.

6 Mar 2018

Experts develop process for marker-free cell selection

At this year's analytica trade fair in Munich, three Fraunhofer Institutes will be presenting a project from pre-competitive research. Biologists, computer scientists and laser experts have developed a process to analyze and select cells and then examine their protein production. In pharmaceutical research, this will make it possible to develop active ingredients much faster than before.

6 Mar 2018

Study uncovers new target in Parkinson’s disease

A new study has uncovered a relationship between the presence of Lewy bodies and neuronal cell death in Parkinson's disease.

6 Mar 2018

Study reveals relationship between circadian rhythm and mitochondrial network

Cellular energy metabolism also follows the rhythm of the circadian clock. A University of Basel study has now shown exactly how this works by revealing the relationship between the circadian rhythm and the mitochondrial network for the first time.

6 Mar 2018

Scientists develop more cost-effective way to culture stem cells

Human pluripotent stem cells can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now, scientists at Japan's Kyoto University, with colleagues in India and Iran, have developed a more cost-effective culture by using a new combination of chemical compounds.

5 Mar 2018