Cell Biology

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Lab-grown skin organoids help scientists understand monkeypox infection

Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.

16 Oct 2023

Study highlights role of circadian clock component BMAL1 on molecular phenotype of senescent cells

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 19, entitled, "BMAL1 modulates senescence programming via AP-1."

16 Oct 2023

Scientists uncover key enzymes involved in bacterial pathogenicity

Gram-negative bacteria cause a variety of infectious diseases in plants and animals alike. Outbreaks of Salmonella and E. coli infections often make headlines due to their severity, and people have to resort to allopathic as well as natural remedies, increasing the burden on the healthcare system.

16 Oct 2023

Calorie restriction may rejuvenate muscles and activate biological pathways for healthy aging

Reducing overall calorie intake may rejuvenate your muscles and activate biological pathways important for good health, according to researchers at the National Institutes of Health and their colleagues.

13 Oct 2023

Researchers create a comprehensive cellular atlas of the Broca’s area in the brain

The brain is made up of numerous types of cells that are organized into different structures and regions.

12 Oct 2023

Scientists unravel secrets about the formation of DNA's building blocks

An international team has uncovered details about the formation of DNA's building blocks, paving the way for potential medical and therapeutic applications.

12 Oct 2023

Study sheds light on how the immune system differentiates between self and non-self antigens

A groundbreaking study, led by Professor Kyemyung Park and his research team in the Graduate School of Health Science and Technology and the Department of Biomedical Engineering at UNIST has shed light on the intricate mechanism behind the immune system's ability to differentiate between self and non-self antigens.

11 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Macrophages play a central role in intestinal cell renewal, study reveals

A research team from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration.

10 Oct 2023

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria.

9 Oct 2023

Midbody remnant found to play role in cancer spread

Once thought to be the trash can of the cell, a little bubble of cellular stuff called the midbody remnant is actually packing working genetic material with the power to change the fate of other cells - including turning them into cancer.

9 Oct 2023

New insights into how neutrophils fight Candida albicans infection

Umeå University researchers, Sweden, unveil how the most common white blood cells, neutrophils, counter Candida albicans toxin stopping its tracks.

5 Oct 2023

New computational method improves analysis of single-cell transcriptomic data

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data.

5 Oct 2023

Selective removal of aging cells represents a new paradigm for treating age-related diseases

A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases.

4 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

30 Sep 2023

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders.

29 Sep 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division.

28 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

Cell Biology

Lab-grown skin organoids help scientists understand monkeypox infection

Study highlights role of circadian clock component BMAL1 on molecular phenotype of senescent cells

Scientists uncover key enzymes involved in bacterial pathogenicity

Calorie restriction may rejuvenate muscles and activate biological pathways for healthy aging

Researchers create a comprehensive cellular atlas of the Broca’s area in the brain

Scientists unravel secrets about the formation of DNA's building blocks

Study sheds light on how the immune system differentiates between self and non-self antigens

DNA aptamers: A versatile tool for regenerative medicine and beyond

Macrophages play a central role in intestinal cell renewal, study reveals

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

Midbody remnant found to play role in cancer spread

New insights into how neutrophils fight Candida albicans infection

New computational method improves analysis of single-cell transcriptomic data

Selective removal of aging cells represents a new paradigm for treating age-related diseases

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Killer T cells in older adults found to be less effective at fighting influenza viruses

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

Monocyte-derived macrophages play a crucial role in liver regeneration

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Researchers describe the origin and fate of liver myofibroblasts

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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