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Ebola survivors and close contacts have high burden of illness

Preliminary findings from PREVAIL III, a study of Ebola virus disease (EVD) survivors being conducted in Liberia, indicate that both Ebola survivors and their close contacts have a high burden of illness. However, the prevalence of eye, musculoskeletal, and neurological complications was greater among the individuals who survived EVD.

25 Feb 2016

Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced the presentation of immunological data from the Company's clinical trials of SB-728-T, a ZFP Therapeutic designed to provide functional control of HIV.

25 Feb 2016

Study: Most Ebola survivors experience brain symptoms more than six months after initial infection

Most of the 82 Ebola survivors in a new study from the world's largest Ebola outbreak had brain symptoms more than six months after the initial infection. The preliminary results will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

25 Feb 2016

Study highlights presence of antibiotic stewardship practices in most VA-affiliated facilities

New research highlights the robust presence of antibiotic stewardship practices in most Veterans Administration-affiliated facilities, manifested in both formal and informal policies. The study was published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Feb 2016

Researchers discover new JE virus transmission route

Japanese Encephalitis (JE) virus causes serious inflammation of the brain in people and fertility problems in pigs. Mosquitoes were previously the only known transmission route. However, the virus can also be spread from pig to pig by direct contact, and this could enable it to circulate in pigs during the mosquito-free winter season.

24 Feb 2016

New research shows copper can destroy MRSA in touch contamination

New research from the University of Southampton shows that copper can destroy MRSA spread by touching and fingertip contamination of surfaces.

24 Feb 2016

UEA research paves way for new wave of drugs to kill superbugs

Scientists at the University of East Anglia are getting closer to solving the problem of antibiotic resistance.

24 Feb 2016

Single dose of zoledronic acid can inhibit bone loss in HIV-infected patients

A single dose of the drug zoledronic acid was found to inhibit the bone loss that is common in HIV-infected patients and that is increased during the first two years of treatment with antiretroviral therapy (ART).

24 Feb 2016

New definitions and clinical criteria for sepsis, septic shock

Clifford S. Deutschman, MS, MD, vice chair of research in the Department of Pediatrics at Cohen Children's Medical Center and an investigator at The Feinstein Institute for Medical Research , presented new definitions and clinical criteria for sepsis and septic shock at the Society of Critical Care Medicine's 45th Critical Care Congress in Orlando, FL.

24 Feb 2016

Influenza virus can able to circumvent the body's immune system

Influenza is able to mask itself, so that the virus is not initially detected by our immune system. This is the result of new research from Aarhus University. The researchers behind the study hope that the discovery can be used to develop better treatment against influenza and chronic inflammation conditions such as rheumatoid arthritis.

24 Feb 2016

ViiV Healthcare presents positive results from LATTE-2 study at CROI

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer Inc. and Shionogi Limited as shareholders, today presented positive results from the LATTE-2 study at the Conference on Retroviruses and Opportunistic Infections (CROI) in Boston. Headline results were announced in November 2015.

24 Feb 2016

First patient dosed in Novan's Phase 3 program to evaluate efficacy of SB204 Gel in treatment of acne

Novan, Inc. today announced that the first patient has been dosed in its Phase 3 program to evaluate the efficacy and safety of its topical nitric oxide product candidate SB204 Gel in the treatment of acne vulgaris ("acne"). The Company is running two identically designed Phase 3 pivotal trials in parallel and expects to report top-line results in the first half of 2017.

23 Feb 2016

Texas Children's Hospital, Houston Methodist Hospital jointly release country's first rapid test for Zika virus

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus.

23 Feb 2016

ARV drug atazanavir may have significant effects on infant development

The antiretroviral (ARV) drug atazanavir—sometimes included in treatments to prevent mother-to-child HIV transmission during pregnancy—may have small but significant effects on infant development, reports a study in the journal AIDS, official journal of the International AIDS Society.

23 Feb 2016

Dapivirine ring can help prevent HIV-1 infection in women

In an important scientific achievement for women's health, two large Phase III clinical trials -- The Ring Study and ASPIRE -- have shown that a monthly vaginal ring containing the antiretroviral drug (ARV) dapivirine can safely help prevent HIV-1 infection in women.

23 Feb 2016

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Researchers at the Medical Faculty of the Technische Universität Dresden and the Heinrich Pette Institute, Leibniz Institute for Experimental Virology succeeded in developing a designer recombinase (Brec1) that is capable of specifically removing the provirus from infected cells of most primary HIV-1 isolates.

23 Feb 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

Study identifies new mechanism for controlling HIV replication

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus.

23 Feb 2016

PharmaEssentia to present results of P1101 + ribavirin phase II trial in HCV patients at APASL 2016

PharmaEssentia Corporation announces presentation of the results of the phase II trial for P1101 + ribavirin in patients with chronic HCV genotype 1 infection at the 25th Conference of the Asian Pacific Association for the Study of the Liver, taking place in Tokyo, Japan from February 20 to 24, 2016 (APASL 2016). Data will be presented by the study coordinating investigator Prof. Wan-Long Chuang (Taiwan) at the HCV parallel oral session on Feb 22nd (15:45-17:45).

22 Feb 2016

Researchers examine socio-ecology, climate responses of Zika virus transmission

Zika: The virus has emerged as a major public health threat that's rapidly spreading through South and Central America and the Caribbean.

22 Feb 2016

Disease/Infection News

Ebola survivors and close contacts have high burden of illness

Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Study: Most Ebola survivors experience brain symptoms more than six months after initial infection

Study highlights presence of antibiotic stewardship practices in most VA-affiliated facilities

Researchers discover new JE virus transmission route

New research shows copper can destroy MRSA in touch contamination

UEA research paves way for new wave of drugs to kill superbugs

Single dose of zoledronic acid can inhibit bone loss in HIV-infected patients

New definitions and clinical criteria for sepsis, septic shock

Influenza virus can able to circumvent the body's immune system

ViiV Healthcare presents positive results from LATTE-2 study at CROI

First patient dosed in Novan's Phase 3 program to evaluate efficacy of SB204 Gel in treatment of acne

Texas Children's Hospital, Houston Methodist Hospital jointly release country's first rapid test for Zika virus

ARV drug atazanavir may have significant effects on infant development

Dapivirine ring can help prevent HIV-1 infection in women

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Study identifies new mechanism for controlling HIV replication

PharmaEssentia to present results of P1101 + ribavirin phase II trial in HCV patients at APASL 2016

Researchers examine socio-ecology, climate responses of Zika virus transmission

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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