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Novel genetic link uncovered in generalized pustular psoriasis

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.

9 Mar 2024

mRNA vaccines train T cells in waves, study shows

mRNA vaccines developed against the spike glycoprotein of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2), displayed remarkable efficiency in combating coronavirus 19 (COVID-19).

9 Mar 2024

Researchers forge new path to combat viruses and cancers with helicase inhibitors

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections-;and, alas, extraordinarily difficult to target with drugs.

9 Mar 2024

Researchers develop precise drugs to target HIV's Nef protein

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

9 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

Man takes 217 COVID vaccines with no ill effects, shows immune boost

A case report of a 62-year-old man receiving 217 SARS-CoV-2 vaccinations over 29 months reveals no adverse effects, increased T-cells, and spike-specific antibodies, providing unique insights into the effects of hyper-vaccination on immune responses.

7 Mar 2024

Understanding long COVID: A call for better diagnosis and treatment

A recent review in Nature Reviews Microbiology summarizes the complex mechanisms, significant impacts, and the urgent need for enhanced diagnostics and treatments for long COVID, affecting over 65 million people globally with diverse, debilitating symptoms and systemic health issues.

7 Mar 2024

UKHSA data shows continued increase in whooping cough cases

New data published today by the UK Health Security Agency (UKHSA) shows there has been a continued increase in pertussis (whooping cough) cases at the start of this year, with 553 confirmed in England in January, compared with 858 cases for the whole of last year (2023).

7 Mar 2024

Proteins regulating plasminogen-plasmin levels can help predict COVID-19 severity

The global impact of the COVID-19 pandemic on healthcare systems has been significant. The sudden surge in infected cases overwhelmed hospitals and disrupted routine healthcare services, thus further worsening public health.

7 Mar 2024

Rapid molecular testing transforms treatment for community-acquired pneumonia

Pneumonia is an inflammatory condition affecting the lungs, typically resulting from an infection with viruses or bacteria.

7 Mar 2024

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024

Researchers discover promising approach to combat multidrug-resistant Salmonella infections

A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports.

7 Mar 2024

COVID-19 booster enhances virus neutralizing antibodies in breast milk, new study reveals

The potential of COVID-19 booster vaccine products (antibodies) passed from mother to offspring through breastmilk.

7 Mar 2024

ECDC raises alarm over rising STI rates across Europe

The findings reveal a troubling surge in cases of syphilis, gonorrhoea, and chlamydia, indicating a pressing need for heightened awareness of STI transmission, and the need to enhance robust prevention, access to testing, and effective treatment to address this public health challenge.

7 Mar 2024