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Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

The study findings reveal that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in abnormal modification of some lung proteins, which are subsequently transported to the brain via exosomes. In the brain, these modified lung proteins disrupt the normal functioning of proteins that are related to Parkinson’s disease.

7 Jun 2021

Accuracy of three COVID-sniffing dogs exceeds 85%

A team of scientists from Italy and Brazil has recently conducted a training program for sniffer dogs to detect coronavirus disease 2019 (COVID-19). They have trained the dogs to accurately sense COVID-19 specific volatile organic compounds in sweat samples collected from COVID-19 patients. The study is currently available on the medRxiv* preprint server.

7 Jun 2021

Patients hospitalized with active cancer are more likely to die from COVID-19

New research indicates that patients hospitalized with active cancer were more likely to die from COVID-19 than those with a history of cancer or those without any cancer diagnosis.

7 Jun 2021

Global land-use changes increase risk of zoonotic coronavirus transmission from bats

Global land-use changes — including forest fragmentation, agricultural expansion and concentrated livestock production — are creating “hotspots” favorable for bats that carry coronaviruses and where conditions are ripe for the diseases to jump from bats to humans, finds a new analysis by researchers at the Politecnico di Milano, University of California, Berkeley and Massey University.

7 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

Vaccination against SARS-CoV-2 with a single dose skin patch

Researchers from Australia recently reported a high-density microarray patch used to deliver a SARS-CoV-2 spike subunit vaccine to the skin directly. They used a combination of a SARS-CoV-2 spike protein vaccine candidate and the high-density microarray patch (HD-MAP) vaccine delivery platform.

7 Jun 2021

Study shows why COVID-19 has widely varying outcomes in different people

The answer is something infectious disease experts are working to uncover. As COVID-19 revealed, the same pathogen can have widely varying outcomes in different people.

7 Jun 2021

Study suggests prolonged, strict restrictions did not necessarily reduce COVID-19 mortality

A multi-national team of researchers compared COVID-19-related data from different countries in order to better understand the various factors leading to the different results across the world. The multi-disciplinary team included data scientists, software developers, and an infectious diseases physician.

7 Jun 2021

International travelers often return home with new bacterial strains, confirms study

Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, suggests new research from Washington University School of Medicine in St. Louis.

7 Jun 2021

Impact of maternal SARS-CoV-2 infection on neonatal immunology

Although extensive studies have been carried out on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and evidence exists that pregnant women are at elevated risk of severe COVID-19, the impact of maternal infection on the fetus is not clear. The majority of pregnant women infected with SARS-CoV-2 are asymptomatic or experience mild symptoms.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

COVID-19 symptoms in the feet

In a review paper recently uploaded to the Journal of Clinical Medicine by Jimenez-Cebrian et al. (May 19th, 2021), the clinical manifestations of COVID-19 in feet, in particular, are reviewed, finding that vascular, dermatological, and neurological symptoms have been widely reported.

6 Jun 2021

High baseline levels of inflammatory cytokines linked to thrombotic events in patients with COVID-19

In a recent open-access paper published in the Journal of Clinical Medicine, researchers from Iran and Germany show that high baseline levels of inflammatory cytokines measured during admission put patients with coronavirus disease (COVID-19) at increased risk of developing coagulopathy, thrombotic events – and even death.

6 Jun 2021

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

New data from CDC on effectiveness of Pfizer and Moderna COVID-19 vaccines

Researchers in the United States have conducted a study demonstrating the real-world effectiveness of the Pfizer-BioNTech and Moderna coronavirus disease 2019 (COVID-19) vaccines at preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jun 2021

Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes

An interesting new bioRxiv* preprint reports the suppression of monocyte glycolysis and cytokine production when exposed to the virus, following pretreatment with the commonly used drug, metformin.

6 Jun 2021

New approach to a wastewater system speeds up detection and tracing of COVID-19

Math continues to be a powerful force against COVID-19. Its latest contribution is a sophisticated algorithm, using municipal wastewater systems, for determining key locations in the detection and tracing of COVID-19 back to its human source, which may be a newly infected person or a hot spot of infected people.

5 Jun 2021

Cancer patients on remote monitoring program less likely to require hospitalization for COVID-19

A study by researchers at Mayo Clinic Cancer Center has found that cancer patients diagnosed with COVID-19 who received care at home via remote patient monitoring were significantly less likely to require hospitalization for their illness, compared to cancer patients with COVID-19 who did not participate in the program.

5 Jun 2021

Analysis finds substantial disparities in COVID-19 rates among patients on hemodialysis in New York City

In an analysis of patients on hemodialysis in New York City, there were substantial racial/ethnic disparities in COVID-19 rates that were not explained by neighborhood social vulnerability.

5 Jun 2021

New study investigates how green tea could lead to a drug for tackling Covid-19

As India continues to be ravaged by the pandemic, a Swansea University academic is investigating how green tea could give rise to a drug capable of tackling Covid-19.

5 Jun 2021

Disease/Infection News

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

Accuracy of three COVID-sniffing dogs exceeds 85%

Patients hospitalized with active cancer are more likely to die from COVID-19

Global land-use changes increase risk of zoonotic coronavirus transmission from bats

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Vaccination against SARS-CoV-2 with a single dose skin patch

Study shows why COVID-19 has widely varying outcomes in different people

Study suggests prolonged, strict restrictions did not necessarily reduce COVID-19 mortality

International travelers often return home with new bacterial strains, confirms study

Impact of maternal SARS-CoV-2 infection on neonatal immunology

Comparison of immunological profiles of SARS-CoV-2 variants

COVID-19 symptoms in the feet

High baseline levels of inflammatory cytokines linked to thrombotic events in patients with COVID-19

Standardizable assay detects T cell responses to SARS-CoV-2 infection

New data from CDC on effectiveness of Pfizer and Moderna COVID-19 vaccines

Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes

New approach to a wastewater system speeds up detection and tracing of COVID-19

Cancer patients on remote monitoring program less likely to require hospitalization for COVID-19

Analysis finds substantial disparities in COVID-19 rates among patients on hemodialysis in New York City

New study investigates how green tea could lead to a drug for tackling Covid-19

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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