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Unique training program is bolstering Canada’s capacity to manufacture novel biotherapeutics

As COVID-19 highlights the urgent need to increase vaccine manufacturing around the world, a unique training program is bolstering Canada's capacity to manufacture vaccines, as well as viral immunotherapies for cancer and other emerging biotherapeutics.

23 Nov 2020

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Marinomed Biotech AG, a globally operating biopharmaceutical company, announced today plans to initiate a Phase IV clinical trial with Carragelose (iota-carrageenan).

23 Nov 2020

Favorable clinical outcome for ivermectin in COVID-19 animal model

A team of researchers at the Institut Pasteur in France has found that ivermectin prevented clinical deterioration in infected animals. The drug also reduced the inflammatory cytokines, interleukin-6 and 10 (IL-6 and IL-10) in lung tissue, which leads to more favorable clinical outcomes in treated animals.

23 Nov 2020

Thromboembolism in COVID-19 patients associated with higher risk of mortality

While respiratory issues continue to be the most common symptom of a COVID-19 infection, new research indicates the disease could also be associated with hypercoagulability, or increased tendency of the blood to clot.

23 Nov 2020

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

At the 73rd Annual Meeting of the American Physical Society's Division of the Americal Physical Society's Division of Fluid Dynamics, researchers presented a range of studies investigating the aerodynamics of infectious disease.

23 Nov 2020

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

This study, published in the journal Cells, is based on others (all of which employed experimental models) previously conducted by researchers at the Biomedical Research Centre of the University of Granada, the ‘López-Neyra’ Institute of Parasitology and Biomedicine, and the ‘Virgen de las Nieves’ University Hospital in Granada

23 Nov 2020

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Nearly a year since the world first learned of the novel coronavirus disease 2019, COVID-19, many questions remain about SARS-CoV-2, the virus behind this pandemic: Where did it come from, how did it spread so widely and rapidly, and how can we stop similar outbreaks in the future?

23 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

New CDC report describes COVID-19 in NYC in early spring

The Centres for Disease Control and Prevention (CDC), in its Morbidity and Mortality Weekly Report (MMWR), has published an update on the outbreak in New York City. The report is titled, "COVID-19 Outbreak — New York City, February 29–June 1, 2020".

23 Nov 2020

New algorithm accurately predicts outcomes for COVID-19 patients

With communities across the nation experiencing a wave of COVID-19 infections, clinicians need effective tools that will enable them to aggressively and accurately treat each patient based on their specific disease presentation, health history, and medical risks.

23 Nov 2020

Study: High blood sugar may worsen COVID-19 outcomes and mortality rates for non-diabetics

Abnormally high blood sugar may worsen outcomes and mortality rates for COVID-19 patients, including those without diabetes, according to major research published in the peer-reviewed open access journal Annals of Medicine.

23 Nov 2020

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Researchers in Brazil have reported two cases of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding infectious virus for a significantly longer period than has previously been reported.

23 Nov 2020

Repeat infection following COVID-19 recovery may not pose risk to close contacts

Researchers in China have conducted a study suggesting that people who have recovered from coronavirus disease 2019 (COVID-19) may not pose a risk to close contacts if they become reinfected with the causative agent severe acute respiratory syndrome coronavirus (SARS-CoV-2).

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Nasal dryness could be an early warning sign of COVID-19

A new study published by an international team of researchers on the preprint medRxiv* server in November 2020 details the nasal symptoms that are associated with anosmia and ageusia (loss of smell and taste) in coronavirus disease 2019 (COVID-19), including the early warning signs of infection.

23 Nov 2020

COVID-19 cases likely to increase to 20 million in the U.S. by end of January 2021

President-elect Joe Biden has signaled that fighting the COVID-19 pandemic will be an immediate priority for his administration. He recently announced a coronavirus advisory board of infectious disease researchers and former public health advisers along with an updated strategy that will include increases in testing and contact tracing, as well as transparent communication.

23 Nov 2020

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

A team of researchers from the USA and China have engineered a receptor-binding domain (RBD) that they claim improves the immunogenicity of multivalent SARS-CoV-2 vaccines. Their study, which was released on the bioRxiv* in November 2020, may help advance even more efficacious SARS-CoV-2 vaccine candidates in the future.

23 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Disease/Infection News

Unique training program is bolstering Canada’s capacity to manufacture novel biotherapeutics

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Favorable clinical outcome for ivermectin in COVID-19 animal model

Thromboembolism in COVID-19 patients associated with higher risk of mortality

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

FDA expands approved indication for influenza treatment to include post-exposure prevention

New CDC report describes COVID-19 in NYC in early spring

New algorithm accurately predicts outcomes for COVID-19 patients

Study: High blood sugar may worsen COVID-19 outcomes and mortality rates for non-diabetics

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Repeat infection following COVID-19 recovery may not pose risk to close contacts

SARS-CoV-2's spike protein mutations have slowed, study finds

How COVID-19 compares to other respiratory illnesses

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Nasal dryness could be an early warning sign of COVID-19

COVID-19 cases likely to increase to 20 million in the U.S. by end of January 2021

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

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