Drug Discovery & Pharmaceuticals

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Upcycling polyethylene waste into pharmacologically useful natural products

Plastic waste is one of the most significant ecological and economic problems of our time. In the journal Angewandte Chemie, a research team has now introduced a chemical–biological method for upcycling polyethylene waste: catalytic cleavage is used to make carboxylic diacids that are subsequently converted into pharmacologically useful natural products by genetically engineered fungi.

30 Nov 2022

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces that it has opened its new facilities in York Science Park, UK, that will enable it to meet the increasing demand for Optimer technology.

From Aptamer Group 30 Nov 2022

New computer-based platform could make drug discovery process more efficient and less expensive

Researchers at The University of Texas at Dallas and Novartis Pharmaceuticals Corp. have devised a computer-based platform for drug discovery that could make the process more effective, more efficient and less costly.

28 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

Optibrium appoints Ian Smith as Chief Technology Officer

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the appointment of Ian Smith as Chief Technology Officer (CTO), the latest in a number of senior-level hires for the Company.

From Optibrium Ltd. 23 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Cancer Research UK’s newly launched innovation engine, Cancer Research Horizons, and Newcastle University, have announced a further significant extension of their strategic drug discovery alliance with Astex Pharmaceuticals (UK) (‘Astex’), a biotechnology company dedicated to the discovery and development of novel small molecule therapeutics.

22 Nov 2022

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Studying the molecular motion of proteins reveals previously unseen binding sites that could be targeted by new drug candidate molecules.

21 Nov 2022

The Native Antigen Company introduces new range of influenza antigens

The Native Antigen Company (part of LGC Clinical Diagnostics), one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, today announced the commercial launch of its latest range of influenza antigens for the southern hemisphere’s 2023 flu season.

From The Native Antigen Company 21 Nov 2022

New Community of Experts launched to harness social media data for patient-centric drug development

The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has launched a new Community of Experts (CoE) to harness real-world data from social media.

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Unique peptides with anti-cancer potential discovered

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Researchers discover new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

11 Nov 2022

ELRIG: Bringing Life Sciences and Drug Discovery Communities Together

We spoke to ELRIG about the evolving landscape of the drug discovery sector, and what actions they are taking to continue to support individuals in this space.

11 Nov 2022

EVIDENT and Ultivue collaborate to advance multiplex slide imaging and spatial analysis in translational research

Evident Corporation, a premier manufacturer of life science imaging systems, and Ultivue, Inc., an industry leader in multiplexing tools and novel image analysis solutions for tissue biomarker studies, announced a collaborative agreement to promote whole slide imaging using multiplexed immunofluorescence (mIF) assays to advance translational research in the Americas.

From Evident Corporation - Life Sciences 10 Nov 2022

Drug Discovery & Pharmaceuticals

Upcycling polyethylene waste into pharmacologically useful natural products

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

New computer-based platform could make drug discovery process more efficient and less expensive

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

Optibrium appoints Ian Smith as Chief Technology Officer

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

The Native Antigen Company introduces new range of influenza antigens

New Community of Experts launched to harness social media data for patient-centric drug development

Rutgers scientists develop new approach to effectively shut down viral infections

Unique peptides with anti-cancer potential discovered

Novel drug could help to fight both COVID-19 and cancer

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Researchers discover new antiviral compounds derived from two Korean native plants

ELRIG: Bringing Life Sciences and Drug Discovery Communities Together

EVIDENT and Ultivue collaborate to advance multiplex slide imaging and spatial analysis in translational research

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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