Drug Discovery & Pharmaceuticals

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New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

In silico studies assess the binding efficacy of phytoconstituents against active sites of SARS-CoV-2.

16 Oct 2022

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Researchers at Baylor College of Medicine and collaborating institutions discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms.

14 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes - or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

New partnership creates an automated anatomic pathology slide-scanning solution

Sakura Finetek, a global leader in histopathology products and Evident Scientific, a wholly owned subsidiary of Olympus Corporation, and a global leader in microscopy and imaging solutions, today announced a collaboration to offer a full workflow solution for anatomic pathology slide preparation and high-resolution digital scanning in the Americas.

From Evident Corporation - Life Sciences 13 Oct 2022

Study offers a systems biology strategy to facilitate the search for effective COVID-19 drugs

A Cleveland Clinic-led research team used artificial intelligence to map out hundreds of ways that the virus that causes COVID-19 interacts with infected cells.

10 Oct 2022

New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

A recent study assesses the neuroprotective potential of the active constituents of cannabis in treating dementia and Alzheimer's disease.

6 Oct 2022

Stanford researchers discover a sustainable way to produce cancer-fighting compound in the lab

Stanford University researchers have discovered a rapid and sustainable way to synthetically produce a promising cancer-fighting compound right in the lab.

3 Oct 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

New compound triggers the same anti-depressant action as rapidly acting psychedelic drugs

While illegal for recreational use, psychedelic drugs are showing great promise as treatments for severe depression and anxiety, as well as alcohol addiction and other conditions.

28 Sep 2022

New Zika vaccine technology found to be highly effective and safe in preclinical mouse models

Researchers from the University of California, Los Angeles have developed a Zika vaccine technology that is highly effective and safe in preclinical mouse models.

28 Sep 2022

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

New Jersey Institute of Technology researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic monoclonal antibodies being developed to treat a variety of diseases, from cancers to infectious diseases.

27 Sep 2022

Metal compounds could be the solution for drug-resistant fungal infections

University of Queensland researchers say metal compounds could be the answer to the growing problem of drug-resistant fungal infections.

26 Sep 2022

Chemical compounds containing special metals can fight fungal infections

An international collaboration led by researchers from the University of Bern and the University of Queensland in Australia has demonstrated that chemical compounds containing special metals are highly effective in fighting dangerous fungal infections.

23 Sep 2022

AI-based drug screening process could speed up the development of life-saving medicines

Developing life-saving medicines can take billions of dollars and decades of time, but University of Central Florida researchers are aiming to speed up this process with a new artificial intelligence-based drug screening process they've developed.

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

In a recent study published in the journal PNAS, researchers from Finland and the United States reported a novel heptad repeat 2 (HR2) peptide that inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without any chemical modifications.

21 Sep 2022

Green tea molecule can break up protein tangles in the brain that cause Alzheimer’s

Scientists at UCLA have used a molecule found in green tea to identify additional molecules that could break up protein tangles in the brain thought to cause Alzheimer's and similar diseases.

20 Sep 2022