Drug Discovery & Pharmaceuticals

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Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick.

28 Oct 2021

McMaster-Hamburg collaboration discovers promising new antimalarial compound

A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound.

27 Oct 2021

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

Medicines come from chemical reactions, and better chemical reactions lead to better medicines.

27 Oct 2021

New computer-aided data tool could improve treatment for many diseases

Scientists from Queen's University Belfast have developed a computer-aided data tool that could improve treatment for a range of illnesses.

26 Oct 2021

UQ-developed oral vaccine marks a leap forward in the battle against hookworm infections

There's been a significant breakthrough in the development of a vaccine to prevent hookworm infection – a parasite which causes serious disease in tens of millions of people globally.

26 Oct 2021

Lactoferrin supplements could be used as adjunct for COVID-19 and other respiratory tract infections

The antiviral properties of lactoferrin makes it a great natural supplement that could also be used as an adjunct for COVID-19 and for various other Respiratory Tract Infections (RTIs) according to a team of researchers led by the University of Huddersfield.

19 Oct 2021

FSU chemists develop a faster way to synthesize compounds for drug development

A team of Florida State University chemists has developed a faster way to synthesize a class of compounds that are commonly used in the development of new medications.

12 Oct 2021

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

A newly detected molecule that helps reduce damage from sustained loss of blood flow to cells and tissues could eventually be used to prevent collateral harm to vital organs during surgery, according to University of Utah Health scientists.

11 Oct 2021

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Scientists at Washington University School of Medicine in St. Louis have developed a compound that prevents SARS-CoV-2 and related coronaviruses from entering cells.

11 Oct 2021

KU Leuven researchers develop an ultrapotent inhibitor of dengue virus

Researchers at the KU Leuven Rega Institute and CD3 have developed an ultrapotent inhibitor of the dengue virus, which causes the tropical disease known as dengue.

6 Oct 2021

Natural substance protects nerve cells from the damage caused by neurodegenerative diseases

University of Tübingen research team investigates bacteria-made agent which may counter the damage of Alzheimer´s disease.

6 Oct 2021

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Researchers at the Centre for Genomic Regulation and Pulmobiotics S.L have created the first 'living medicine' to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. The researchers created the treatment by removing a common bacteria's ability to cause disease and repurposing it to attack harmful microbes instead.

6 Oct 2021

Scientists use new technique to study the effects of reactive electrophilic drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation damages the protective myelin insulation around nerves, and the nerves themselves.

30 Sep 2021

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

Aptamer Group and BizCom announce collaboration for Optimer distribution and marketing services in Japan.

From Aptamer Group 29 Sep 2021

The new FlowCam® LO improves particle characterization in drug development

Yokogawa Fluid Imaging Technologies announces the release of the FlowCam® LO, the first and only light obscuration instrument with imaging capabilities.

From Yokogawa Fluid Imaging Technologies, Inc. 29 Sep 2021

Scientists develop 'elite' antibodies capable of defeating coronavirus variants at extremely low dosage

Japanese scientists created "elite" antibodies that defeat various coronavirus variants even at an extremely low dose through a new method that accelerated the months-long process of finding such extraordinary antibody candidates to just ten days.

27 Sep 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Drug Discovery & Pharmaceuticals

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

McMaster-Hamburg collaboration discovers promising new antimalarial compound

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

New computer-aided data tool could improve treatment for many diseases

UQ-developed oral vaccine marks a leap forward in the battle against hookworm infections

Lactoferrin supplements could be used as adjunct for COVID-19 and other respiratory tract infections

FSU chemists develop a faster way to synthesize compounds for drug development

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

KU Leuven researchers develop an ultrapotent inhibitor of dengue virus

Natural substance protects nerve cells from the damage caused by neurodegenerative diseases

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Scientists use new technique to study the effects of reactive electrophilic drugs

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

The new FlowCam® LO improves particle characterization in drug development

Scientists develop 'elite' antibodies capable of defeating coronavirus variants at extremely low dosage

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Discovery points toward a new strategy for treating Parkinson's disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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