Drug Discovery & Pharmaceuticals

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Study may help overcome some obstacles to the development of nanoparticle-based drugs

Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy.

21 Jul 2022

Antibiotics have sex-specific effects on the gut microbiome, preclinical study finds

In a new study, researchers at Cedars-Sinai found that antibiotics have sex-specific effects on the gut microbiome makeup of male and female laboratory rats. The findings, published in the journal Frontiers in Microbiology, could have implications for using the drugs in humans to treat or prevent bacterial infection.

20 Jul 2022

Combinations of broadly neutralizing antibodies may be a more effective approach to treat HIV

Carefully designed cocktails of broadly neutralizing antibodies (bNAbs) could help treat HIV while minimizing the risk of the virus escaping treatment, suggests a study published today in eLife.

20 Jul 2022

Scientists find new evidence against using BET inhibitors to treat COVID-19

A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

20 Jul 2022

Potential mRNA vaccines for influenza

Scientists discuss the benefits of shifting the global influenza vaccination system to a mRNA-based platform,

19 Jul 2022

New vaccine shows promise to fight Lassa virus

Researchers at the University of Texas Medical Branch have achieved success with a new vaccine developed to fight Lassa Virus, a pathogen that causes Lassa fever.

19 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Novel technique could offer an improved route to drug discovery and development

A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.

14 Jul 2022

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Vaccines may need to dig a little deeper to stop SARS-CoV-2. Rice University researchers are providing a new shovel.

14 Jul 2022

Using microparticles to create 'self-boosting' vaccines

Most vaccines, from measles to Covid-19, require a series of multiple shots before the recipient is considered fully vaccinated.

13 Jul 2022

Bioactive compounds in a marine sponge show potential to kill antibiotic-resistant bacteria

A research group led by scientists at the University of São Paulo (USP) in São Carlos, Brazil, has identified a number of bioactive compounds in a marine sponge collected on Fernando de Noronha, an archipelago about 400 km off the coast of Brazil's Northeast region.

13 Jul 2022

New approach could pave the way for development of pan-coronavirus antivirals

To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections.

13 Jul 2022

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Researchers at the AIDS Institute, The University of Hong Kong, Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong and the State Key Laboratory of Emerging Infectious Diseases, HKU, together with structural biologists at The Hong Kong University of Science and Technology, have demonstrated that ZCB11, a broadly neutralizing antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2.

13 Jul 2022

Production of anti-SARS-CoV-2 antibodies from hyperimmunized chickens

A new study reports the production of neutralizing antibodies against SARS-CoV-2 in hyperimmunized hens.

12 Jul 2022

Novel COVID-19 antibody delivery approach advances to clinical trials

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

7 Jul 2022

New biosensor system derived from E. coli bacteria could accelerate drug development

For more affordable, sustainable drug options than we have today, the medication we take to treat high blood pressure, pain or memory loss may one day come from engineered bacteria, cultured in a vat like yogurt.

7 Jul 2022

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

DZNE and Intravacc B.V., a world leading contract development and manufacturing organization (CDMO) of preventive and therapeutic vaccines, have been awarded a funding of € 2.5 million from the European Union (EIC Transition Grant) to further develop a prototype ALS vaccine, including process development, scale-up, and toxicology study.

6 Jul 2022

BICO; Combining Life Sciences Solutions to Further Human Health

As part of our SLAS Europe 2022 coverage, we speak to Héctor Martínez, CTO of BICO, about the technology and services they offer within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 5 Jul 2022

Generation of live attenuated influenza A virus vaccine using PROTAC technology

A promising strategy to reduce the impact of viral infectious diseases, such as influenza, is the use of attenuated, live viruses as vaccines.

4 Jul 2022

Drug Discovery & Pharmaceuticals

Study may help overcome some obstacles to the development of nanoparticle-based drugs

Antibiotics have sex-specific effects on the gut microbiome, preclinical study finds

Combinations of broadly neutralizing antibodies may be a more effective approach to treat HIV

Scientists find new evidence against using BET inhibitors to treat COVID-19

Potential mRNA vaccines for influenza

New vaccine shows promise to fight Lassa virus

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

Novel nanoligomer approach to treat severe COVID-19

Novel technique could offer an improved route to drug discovery and development

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Using microparticles to create 'self-boosting' vaccines

Bioactive compounds in a marine sponge show potential to kill antibiotic-resistant bacteria

New approach could pave the way for development of pan-coronavirus antivirals

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Production of anti-SARS-CoV-2 antibodies from hyperimmunized chickens

Novel COVID-19 antibody delivery approach advances to clinical trials

New biosensor system derived from E. coli bacteria could accelerate drug development

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

BICO; Combining Life Sciences Solutions to Further Human Health

Generation of live attenuated influenza A virus vaccine using PROTAC technology

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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