Drug Discovery & Pharmaceuticals

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Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally.

13 Jul 2021

New approach that uses machine learning could transform drug development

Writing in the July 12, 2021 online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

12 Jul 2021

Scientists discover drug candidates for treating liver fibrosis among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies -- among pest control chemicals.

8 Jul 2021

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays.

8 Jul 2021

Common anti-coagulant drug could treat emerging variants of SARS-CoV-2

QUT PhD researcher Zachariah Schuurs said the research team had identified a new binding site on the SARS-CoV-2 spike protein.

7 Jul 2021

New screening method tests the effectiveness of drug compounds that 'glue' proteins together

A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed by researchers at the University of Birmingham and the University of Leicester.

7 Jul 2021

Researchers reveal a promising target for designing anti-cancer therapies

Chances are, every one of us has been affected by cancer in one way or another. Unlike some other deadly diseases, cancer can take many forms inside the human body, so learning more about a single enzyme linked to many types of this disease could lead to more effective treatments.

2 Jul 2021

Anti-malarial drug shows promise in the battle against COVID-19

In the "war" that the world has been fighting against COVID-19, scientists have been scanning their arsenals of previously used drugs in hopes of finding any that can be used to treat the disease.

1 Jul 2021

FairJourney Biologics introduces “THE ANTIBODY SERIES” conference

FairJourney Biologics S.A. (FJB), leaders in the discovery and optimization of antibodies, today announced the launch of the “THE ANTIBODY SERIES” - a 1-day conference bringing together top experts in the antibody field to explore the latest innovation within antibody drug discovery.

From FairJourney Biologics S.A. 1 Jul 2021

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

Researchers from collaborating universities in Virginia have recently utilized transgenic mice to explore the effects of SARS-CoV-2 on associated lung injury.

30 Jun 2021

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

Skoltech researchers and their colleagues from Russia and the UK investigated the safety and efficacy of new chemistry in antisense oligonucleotides used to treat spinal muscular atrophy (SMA), a debilitating genetic disease.

29 Jun 2021

Novel approach to molecular drug design paves way for promising bladder cancer therapy

A new approach to molecular drug design has yielded a highly promising bladder cancer drug, which induced rapid shedding of tumor cells and resulted in a significant reduction in tumour size when used in clinical trials.

28 Jun 2021

New molecule extracted from the leaves of chestnut tree neutralizes staph bacteria

Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria. Frontiers in Pharmacology published the finding, led by scientists at Emory University.

28 Jun 2021

Sunflower peptide identified as a potential drug for treating abdominal pain

A naturally occurring peptide in sunflower seeds was synthetically optimised and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area and/or internal organs).

28 Jun 2021

Yeast-derived polysaccharide mixture effectively inhibits the onset, progression of immune disorders

The development of therapeutic drugs for inflammatory bowel disease, an intractable immune disease, and multiple sclerosis - an autoimmune disorder - is gaining traction.

25 Jun 2021

WEHI collaborates with Boehringer Ingelheim to develop novel anti-cancer therapeutics

WEHI has partnered with Boehringer Ingelheim, a leading research-driven pharmaceutical company, in a collaboration to discover and develop anti-cancer therapeutics using a promising new technology called targeted protein degradation.

25 Jun 2021

Researchers reanalyze COVID RECOVERY trial data on tocilizumab

A Bayesian analysis of the RECOVERY trial suggests the immunosuppressive drug tocilizumab can reduce deaths in hospitalized COVID-19 patients taking corticosteroids as well as patients on oxygen or non-invasive ventilation and likely increases hospital discharge rates. However, it is not clear if patients on invasive ventilation also benefit.

24 Jun 2021

Molecule derived from tarantula venom may help relieve chronic IBS pain

For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom.

23 Jun 2021

Caterpillar’s venom shows promise for use in medicines, pest control

The venom of a caterpillar, native to South East Queensland, shows promise for use in medicines and pest control, Institute for Molecular Bioscience researchers say. The Doratifera vulnerans is common to large parts of Queensland's south-east and is routinely found in Toohey Forest Park on Brisbane's southside.

23 Jun 2021

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

How do you kill tumor cells that can't be targeted? Get their more susceptible neighbors to help.

22 Jun 2021

Drug Discovery & Pharmaceuticals

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

New approach that uses machine learning could transform drug development

Scientists discover drug candidates for treating liver fibrosis among pesticides

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

Common anti-coagulant drug could treat emerging variants of SARS-CoV-2

New screening method tests the effectiveness of drug compounds that 'glue' proteins together

Researchers reveal a promising target for designing anti-cancer therapies

Anti-malarial drug shows promise in the battle against COVID-19

FairJourney Biologics introduces “THE ANTIBODY SERIES” conference

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

Novel approach to molecular drug design paves way for promising bladder cancer therapy

New molecule extracted from the leaves of chestnut tree neutralizes staph bacteria

Sunflower peptide identified as a potential drug for treating abdominal pain

Yeast-derived polysaccharide mixture effectively inhibits the onset, progression of immune disorders

WEHI collaborates with Boehringer Ingelheim to develop novel anti-cancer therapeutics

Researchers reanalyze COVID RECOVERY trial data on tocilizumab

Molecule derived from tarantula venom may help relieve chronic IBS pain

Caterpillar’s venom shows promise for use in medicines, pest control

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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