Drug Discovery & Pharmaceuticals

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'Combination' adjuvant may boost the protective power of vaccines

Scientists at La Jolla Institute for Immunology and Massachusetts Institute of Technology, have found a possible way to improve the effectiveness of COVID-19 vaccines - and any vaccine.

4 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant - a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Researchers investigate the antiviral activities of SSPS extracted from green seaweed Ulva sp. to demonstrate the anti-SARS-CoV-2 activity of ulvans.

2 Dec 2021

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.

1 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

bit.bio appoints Kathryn Corzo as Chief Operating Officer

Cell coding company bit.bio today announces the key appointment of Kathryn Corzo as Chief Operating Officer. She started in the role on 1 November 2021.

From bit.bio 19 Nov 2021

New target for drug development could fill a major gap in depression treatment

Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects.

10 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

A team of scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of SARS-CoV-2 in respiratory samples.

4 Nov 2021

Yokogawa Acquires Insilico Biotechnology, Developer of Innovative Bioprocess Digital Twin Technology - Enabling solutions for biopharmaceutical development and production -

Yokogawa announces that it has acquired all shares of Insilico Biotechnology AG (“Insilico”), a Stuttgart, Germany-based developer and provider of bioprocess software and services.

From Yokogawa Electric Corporation 3 Nov 2021

Rice introduces new online portal to help researchers screen COVID-19 drug candidates

Rice University researchers have introduced an online portal to help researchers screen COVID-19 drug candidates that might attack specific proteins of the SARS-CoV-2 virus.

1 Nov 2021

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Drug Discovery & Pharmaceuticals

'Combination' adjuvant may boost the protective power of vaccines

New nanoparticle adjuvant could help make vaccines more powerful

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Experimental compound reduces diabetic complications in mice

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

bit.bio appoints Kathryn Corzo as Chief Operating Officer

New target for drug development could fill a major gap in depression treatment

New discovery could lead to the creation of a pan-coronaviruses vaccine

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

Yokogawa Acquires Insilico Biotechnology, Developer of Innovative Bioprocess Digital Twin Technology - Enabling solutions for biopharmaceutical development and production -

Rice introduces new online portal to help researchers screen COVID-19 drug candidates

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

The Surgeon-Scientist Pioneering Regenerative Engineering

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

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