Drug Discovery & Pharmaceuticals

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Scientists develop new resource-saving green alternative for drug production

For the production of drugs, pesticides and smartphone displays, most of the processes are cost-intensive and generate a large amount of waste. Scientists at the University of Göttingen have now succeeded in developing a resource-saving "green" alternative. The results were published in Nature Catalysis.

8 Jan 2019

CytoReason enters into drug discovery collaboration agreement with Pfizer

CytoReason, a leader in machine learning for drug discovery and development, announced today that it has entered into a collaboration agreement with Pfizer Inc. that will leverage CytoReason's cell-centered models of the immune system.

8 Jan 2019

Inhalable mRNA offers hope for patients with lung disease

Scientists have reported the success of an inhalable mRNA therapy that can induce the production of a target protein in the lungs of mice.

4 Jan 2019

Insilico to present 'AI-powered end-to-end pipelines for drug discovery' at Longevity Therapeutics 2019

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at The Longevity Therapeutics 2019 in San Francisco, 30 of January.

30 Dec 2018

Novel ferrocenyl phosphines developed as potent antimalarial drugs

A team of researchers from the Singapore University of Technology and Design and Nanyang Technological University have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death.

20 Dec 2018

Researchers synthesize new compound that inhibits replication of hepatitis C virus

A new compound that inhibits the replication of hepatitis C virus in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by researchers at São Paulo State University in Brazil.

19 Dec 2018

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

DNA “webs” shown to promote metastasis in ovarian cancer

Researchers have found that neutrophils cast DNA “webs” that aid the spread of ovarian cancer cells to new tissues (a process known as metastasis).

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Researchers have discovered that the ER translocation of MAPK leads to drug resistance in melanoma.

18 Dec 2018

National Biofilms Innovation Centre award grant to Neem Biotech for novel anti-biofilm drug development

Neem Biotech, Welsh Wound Innovation Centre and Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms Awarded NBIC Grant to Advance Development of Neem’s First-in-Class Treatments for Wound Infections.

From Neem Biotech 17 Dec 2018

Getting the Most Out of the CLARITY Technique

An interview with Dr. Tim Steppe, discussing the latest advances in the CLARITY technique and his top tips for scientists using this method in their research.

From Logos Biosystems 17 Dec 2018

Answering the Biggest Neurological Research Questions of Today

An interview with Dr. Peggy Taylor, discussing the biggest neurological research questions of today and how BioLegend is helping to develop new biomarkers for neurological disease.

From BioLegend 14 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Microbiological analysis of bacteria that cause food poisoning could save lives

Researchers have made an important discovery that could help save patients with bacterial infections, particularly those suffering from food poisoning.

12 Dec 2018

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Dr. John McCafferty celebrates the success of phage display technology with Nobel Prize in Chemistry Laureates.

From FairJourney Biologics 12 Dec 2018

Integral Molecular and Merus collaborate to develop bispecific antibody therapeutics

Integral Molecular, the industry leader in the discovery of monoclonal antibodies against membrane proteins, and Merus N.V., a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics, announced that they have entered into a collaboration on multiple undisclosed targets.

12 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Absolute Antibody announces major new expansion

Antibody specialist Absolute Antibody Ltd has announced a major new expansion to its site in North East England. The company opened a production facility in the area just two years after it was founded in Oxford in 2012, and has undergone rapid expansion since then.

From Absolute Antibody 4 Dec 2018

Drug Discovery & Pharmaceuticals

Scientists develop new resource-saving green alternative for drug production

CytoReason enters into drug discovery collaboration agreement with Pfizer

Inhalable mRNA offers hope for patients with lung disease

Insilico to present 'AI-powered end-to-end pipelines for drug discovery' at Longevity Therapeutics 2019

Novel ferrocenyl phosphines developed as potent antimalarial drugs

Researchers synthesize new compound that inhibits replication of hepatitis C virus

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

DNA “webs” shown to promote metastasis in ovarian cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Developing the Next Generation of Water-soluble DREADDs

Researchers discover how MAPK translocation leads to drug resistance in melanoma

National Biofilms Innovation Centre award grant to Neem Biotech for novel anti-biofilm drug development

Getting the Most Out of the CLARITY Technique

Answering the Biggest Neurological Research Questions of Today

New discovery will improve the safety and predictability of CRISPR

Microbiological analysis of bacteria that cause food poisoning could save lives

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Integral Molecular and Merus collaborate to develop bispecific antibody therapeutics

Customizing Genetically Engineered Models for Specific Research Applications

Absolute Antibody announces major new expansion

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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