Drug Discovery & Pharmaceuticals

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Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Research drug may one day be novel treatment for systemic inflammatory response syndrome

When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection.

11 Jun 2018

International experts agree on need for human-relevant research to improve drug discovery

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

8 Jun 2018

Neem Biotech present biofilm disruptor at BIO Boston 2018, to minimise antimicrobial resistance

Neem Biotech, a Wales based pharmaceutical biotech working in the field of novel antimicrobial research and development will present details of the company’s approach to minimising antimicrobial resistance through biofilm disruption at BIO Boston 2018.

From Neem Biotech 7 Jun 2018

Microbiotica collaborates with Genentech to develop drugs for IBD

Microbiotica, a leading player in microbiome-based therapeutics spun out of the Wellcome Sanger Institute, today announced that it has entered into a multi-year strategic collaboration with Genentech, a member of the Roche Group, to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease.

6 Jun 2018

IONTAS collaborates with LG Chem to discover antibodies for treating cancer

IONTAS Limited, a leader in the discovery and optimisation of fully human antibodies, today announced it has signed a collaboration agreement with Korean-based LG Chem, Ltd. for the discovery of therapeutic antibodies targeting undisclosed targets for use in the treatment of cancers.

5 Jun 2018

Study identifies four tumor survival strategies in childhood cancer

Researchers have identified four main trajectories for the development of childhood cancer, two of which have been linked to disease relapse.

5 Jun 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018

Researchers use nanoparticles to predict heavy wound scarring

Researchers have developed a new way of seeing heavy wound scars as they form, using nanoparticles that enable early intervention by doctors.

4 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

UK scientists 3D-print the first human corneas

For the first time in history, scientists from have 3D-printed human corneas, providing a potential solution to the current shortage of corneas for transplant.

1 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Study shows blood stem cells compensate for immune cell deficiencies

Researchers have shown that if certain blood stem cells that produce immune cells are deficient, other blood stem cells compensate by overproducing the immune cells that are lacking.

30 May 2018

Researchers uncover the cause of rheumatoid arthritis

A team of researchers have identified the cellular network involved in initiating and maintaining chronic inflammation in rheumatoid arthritis.

30 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

Novoheart announces next generation of 'Human heart-in-a-jar' technology for advanced drug discovery

Novoheart today announced that the next generation of its ‘Human heart-in-a-jar’ technology - which makes up a key component of its comprehensive MyHeartTM Platform - will be unveiled for the first time at the Annual Meeting of the International Society for Stem Cell Research, held in Melbourne, Australia from 20-23 June, 2018.

26 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

DNA vaccine shows promise for colorectal cancer

For the first time in humans, researchers are testing a combined approach to treating advanced stage colorectal cancer (CRC) that may be life-changing for patients.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Prof. Jonathan Wingfield, AstraZeneca, describes the collaboration with Labcyte and Waters to develop a high throughput mass spectrometry platform.

From Pittcon 18 May 2018

Drug Discovery & Pharmaceuticals

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Research drug may one day be novel treatment for systemic inflammatory response syndrome

International experts agree on need for human-relevant research to improve drug discovery

Neem Biotech present biofilm disruptor at BIO Boston 2018, to minimise antimicrobial resistance

Microbiotica collaborates with Genentech to develop drugs for IBD

IONTAS collaborates with LG Chem to discover antibodies for treating cancer

Study identifies four tumor survival strategies in childhood cancer

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

Researchers use nanoparticles to predict heavy wound scarring

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

UK scientists 3D-print the first human corneas

Discovering Antibodies with Universal Specificity

Study shows blood stem cells compensate for immune cell deficiencies

Researchers uncover the cause of rheumatoid arthritis

Researchers identify novel target for bladder cancer

Novoheart announces next generation of 'Human heart-in-a-jar' technology for advanced drug discovery

Mapping the Genes Responsible for Pluripotency

DNA vaccine shows promise for colorectal cancer

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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