Drug Discovery & Pharmaceuticals

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Discovery about how malaria moves could lead to new therapies

Researchers have made an important discovery about how Plasmodium falciparum (the parasite that causes malaria) is able to evade capture by the immune system.

23 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018

Scientists discover protein regulator of myelin production

Scientists have made an important discovery about the role of a protein called PRMT5 in the production of myelin.

19 Jul 2018

Biophysicists use infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum have succeeded in analyzing quickly and easily which active agents affect the structure of proteins and how long that effect lasts.

19 Jul 2018

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

In a new SLAS Discovery article, Helen Yu and a team of researchers at Gilead Sciences, Inc. present a time-resolved fluorescence resonance energy transfer-based Bruton's tyrosine kinase occupancy assay that can measure target engagement in peripheral blood mononuclear cells and in lymph-node and bone-marrow samples.

17 Jul 2018

New molecule shows great promise for future treatment of many cancers

A new molecule designed by University of Adelaide researchers shows great promise for future treatment of many cancers.

17 Jul 2018

New class of chemical compounds has potential for treating Zika virus and RSV

A new and promising class of chemical compounds has major potential for treating Zika virus and respiratory syncytial virus, or RSV, according to a new study by University of Alberta scientists. The next step is to develop a drug.

12 Jul 2018

Stem cell study brings scientists closer to understanding schistosomiasis

Scientists have made an important discovery that could lead to the development of new treatments for schistosomiasis, a common parasitic disease.

10 Jul 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

Machine-learning model automates design of new molecules to accelerate drug development

Designing new molecules for pharmaceuticals is primarily a manual, time-consuming process that's prone to error. But MIT researchers have now taken a step toward fully automating the design process, which could drastically speed things up -- and produce better results.

9 Jul 2018

3D Printing Technology and Personalized Medicine

In this interview Dr. Serajuddin, Professor of Industrial Pharmacy at St John's University talks about personalized medicine and 3D printing technology.

From Thermo Fisher Scientific – Materials Characterization 6 Jul 2018

Scientists discover potential new drug to treat two life-threatening tropical diseases

Derived from nature, a potential new drug to treat two life-threatening tropical diseases has been discovered as a result of collaboration between two Welsh universities.

5 Jul 2018

Scientists synthesize new compound with anticarcinogenic properties

The patent has been registered from the University of Seville and licensed by the British company Evgen Pharma, which is currently developing programmes aimed at breast cancer, subarachnoid haemorrhage and multiple sclerosis, among others

5 Jul 2018

Drug combinations alter effectiveness of antibiotics

The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives.

4 Jul 2018

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Innovative synthetic technique opens door to new world of cutting-edge medicinal compounds

In pharmacology, not all molecular structures are created equal. Some frameworks are overrepresented in nature, making them especially attractive to scientists on the hunt for more effective drugs.

4 Jul 2018

Lonza launches new website to support bioresearch, drug discovery scientists

Lonza Bioscience is inviting visitors to explore its new dedicated website: bioscience.lonza.com. Filled with detailed application and product information, the website has been designed to support the work of scientists across the bioresearch, drug discovery and pharmaceutical manufacturing fields.

From Lonza 3 Jul 2018