Drug Discovery & Pharmaceuticals

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Study shows promising prospects for automating 3D-DSRT in drug testing

The June 2023 issue of SLAS Discovery contains one review article, five full-length articles and two technical briefs covering spheroid models, 3D cell high-throughput screening (HTS) applications for treating Alzheimer's and other drug discovery research.

29 Jun 2023

Albumedix enters into collaboration agreement with Cell and Gene Therapy Catapult

Albumedix Ltd., an enabler of advanced therapies and the world leader in recombinant human albumin (rAlb), announced today that they have entered into a collaboration agreement with Cell and Gene Therapy Catapult (CGT Catapult) to investigate the use of Albumedix´ proprietary albumin-based solutions for advanced therapy applications, including viral vectors manufacturing.

From Albumedix Ltd. 29 Jun 2023

Albumedix and Valneva expand collaboration to include newly approved inactivated COVID-19 vaccine

Albumedix Ltd., a recognized global leader in Recombinant Human Albumin (rHA), specializing in the enablement of advanced therapies and biopharmaceuticals, today announces the expansion of its existing collaboration with Valneva SE, a specialty vaccine company focused on prevention of infectious diseases with significant unmet medical need.

From Albumedix Ltd. 29 Jun 2023

Newly identified enzyme could be a useful tool for creating anticancer drugs

Many of the drugs we use to treat cancer and infectious disease are ⎯ or derive from ⎯ natural products, but it's difficult to know exactly how nature assembles them.

27 Jun 2023

A new approach for the synthesis of pharmaceutically relevant fluorinated phenanthridines

Phenanthridines are heterocyclic compounds consisting of two six-membered benzene rings fused to a six-membered ring containing nitrogen.

26 Jun 2023

Stanford and Intonation partner to develop new treatments for neuroendocrine tumors

Stanford University's Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories (Intonation) have formed a collaboration to develop treatments that target cancerous neuroendocrine tumors, or tumors that form from hormone-releasing cells.

23 Jun 2023

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery."

21 Jun 2023

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

ACROBiosystems, through ACRO Certify and under its Aneuro brand, recently announced the launch of in vivo electrophysiology solutions for neuroscience research with Diagnostic Biochips.

From ACROBiosystems 19 Jun 2023

MGI and AddLife AB Announce Strategic Collaboration for Expanded Distribution of MGI products* in the Nordic Region

MGI Tech Co. Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, are delighted to announce a comprehensive collaboration with AddLife AB, one of Europe's largest distributors of clinical testing and laboratory equipment, headquartered in Stockholm.

From MGI 16 Jun 2023

Breast cancer drug development work moves forward with support from STTR grant

Triple negative breast cancer is an aggressive subtype of breast cancer with worse survival outcomes than most.

14 Jun 2023

Synthetic compound used in perfumes shows potential to stop coagulopathy during a massive hemorrhage

The chances of surviving massive blood loss from a traumatic injury such as a gunshot wound are around 50 percent. To survive, a patient needs two things to happen quickly: a large infusion of blood and coagulation at the wound to stop the bleeding.

14 Jun 2023

Molecule found in the venomous toadfish controls lung inflammation in mice

A molecule found in the venomous toadfish Thalassophryne nattereri has proved capable of controlling lung inflammation and could be the basis for a more effective asthma drug.

13 Jun 2023

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

13 Jun 2023

Berlin scientists further improve nasal vaccine against coronavirus

After having successfully tested a mucosal vaccine against coronavirus in animals just months ago, Berlin scientists have now further developed their live SARS-CoV-2 vaccine.

13 Jun 2023

Keynote speakers of ELRIG Drug Discovery 2023 announced

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for Drug Discovery 2023, taking place at the ACC in Liverpool from 18–19 October. Prof Janet Hemingway CBE, FRS, Founding Director of Infection Innovation Consortium (iiCON), and Dr Dave Powell, Chief Scientific Officer (CSO) of LifeArc will lead this year’s event focussing on diverse thinking and new perspectives.

10 Jun 2023

New model can quickly screen large libraries of potential drug compounds

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease.

9 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

New process can help to design drugs with fewer or no side effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

7 Jun 2023

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Axol Bioscience Ltd. (Axol), a leading pluripotent stem cell technology provider for drug discovery has signed an exclusive agreement with StrataStem to access and commercialize its extensive collection of Alzheimer’s Disease (AD) patient samples.

From Axol Bioscience Ltd 7 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

Drug Discovery & Pharmaceuticals

Study shows promising prospects for automating 3D-DSRT in drug testing

Albumedix enters into collaboration agreement with Cell and Gene Therapy Catapult

Albumedix and Valneva expand collaboration to include newly approved inactivated COVID-19 vaccine

Newly identified enzyme could be a useful tool for creating anticancer drugs

A new approach for the synthesis of pharmaceutically relevant fluorinated phenanthridines

Stanford and Intonation partner to develop new treatments for neuroendocrine tumors

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

MGI and AddLife AB Announce Strategic Collaboration for Expanded Distribution of MGI products* in the Nordic Region

Breast cancer drug development work moves forward with support from STTR grant

Synthetic compound used in perfumes shows potential to stop coagulopathy during a massive hemorrhage

Molecule found in the venomous toadfish controls lung inflammation in mice

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Berlin scientists further improve nasal vaccine against coronavirus

Keynote speakers of ELRIG Drug Discovery 2023 announced

New model can quickly screen large libraries of potential drug compounds

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

New process can help to design drugs with fewer or no side effects

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Breakthrough: Sequencing functional antibody proteins directly from human blood

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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