Drug Discovery & Pharmaceuticals

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Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Axol Bioscience Ltd. (Axol), a leading pluripotent stem cell technology provider for drug discovery has signed an exclusive agreement with StrataStem to access and commercialize its extensive collection of Alzheimer’s Disease (AD) patient samples.

From Axol Bioscience Ltd 7 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

ELRIG UK Announces Prof Janet Hemingway and Dr Dave Powell as Keynote Speakers at Drug Discovery 2023

ELRIG Drug Discovery 2023 at ACC Liverpool (18–19 October) to focus on diverse thinking and new perspectives.

From ELRIG (UK) Ltd. 6 Jun 2023

Simplifying AI data analysis for scientists – as REPROCELL, IBM and STFC Hartree Centre successfully launch Pharmacology-AI platform

REPROCELL today announces the launch of a new commercial service, Pharmacology-AI.

From REPROCELL 2 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Using generative AI to accelerate the drug development process

While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development process.

30 May 2023

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

30 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Academic paper: AI is advantageous in all aspects of new drug research and development

Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded.

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19.

22 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Melanin structure discovery brings scientists one step closer to developing ultra-protective sunscreen

A new discovery about the structure of melanin has brought scientists one step closer to developing a new, potentially ultra-protective sunscreen derived from a biological substance found in nearly all organisms.

18 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body.

15 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.