Drug Discovery & Pharmaceuticals

RSS

Optibrium appoints computational modelling expert, Dr Hamed Tabatabaei Ghomi as Head of Research

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the appointment of Dr Hamed Tabatabaei Ghomi as Head of Research.

From Optibrium Ltd. 4 Apr 2023

MIP Discovery announces drugs of abuse reagent launch

MIP Discovery, a leader in rationally designed detection reagents based on its proprietary nanoMIP technology, in response to the growing synthetic opioid crisis has announced the launch of its first drugs of abuse products which are able to recognize norfentanyl, the main urinary metabolite of fentanyl.

From MIP Discovery 4 Apr 2023

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Researchers discuss the challenges impeding the development of vaccines against flaviviruses.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Study paves the way for wider applications of cell reprogramming in medicine

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

29 Mar 2023

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

28 Mar 2023

New molecule slows the effects of one of SARS-CoV-2's more dangerous components

Researchers have designed a molecule that slows the effects of one of SARS-CoV-2's more dangerous components – an enzyme called a protease that cuts off the immune system's communications and helps the virus replicate.

28 Mar 2023

Understanding Mtb's nitrogen metabolism could pave the way for more effective TB treatments

Development of new drugs to effectively target the bacterium that causes tuberculosis (TB) could be one step closer following an important discovery from the University of Surrey.

27 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report March 24th in the journal Molecular Therapy.

24 Mar 2023

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value.

23 Mar 2023

Naturally-occurring compound found in trees effective in fighting superbugs

Researchers at the University of Portsmouth have discovered that a naturally-occurring compound found in trees is effective in combating superbugs.

22 Mar 2023

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2.

22 Mar 2023

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

Gyros Protein Technologies AB today announced the launch of three service offerings to support development and manufacturing of peptide-based drugs.

From Gyros Protein Technologies AB 22 Mar 2023

Snapping at new biotech breakthroughs with Gator Pro

In this interview, we speak to Subodh Nimkar, Marketing Director at Gator Bio, about their latest technology, Gator Pro which allows for fast, reliable, and high-quality data.

From Gator Bio, Inc. 21 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

Newly identified small molecule may help treat people with drug-resistant epilepsy

Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures.

15 Mar 2023

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.