Drug Discovery & Pharmaceuticals

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New method revolutionizes DNA-encoded chemical libraries

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies.

2 Sep 2024

New method accelerates drug discovery from years to months

Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery.

30 Aug 2024

Innovative nickel tool enhances organic chemical reactions for drug creation

The invention of a tool capable of unlocking previously impossible organic chemical reactions has opened new pathways in the pharmaceutical industry to create effective drugs more quickly.

30 Aug 2024

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Industrial biotech specialist Ingenza is delighted to announce that it is collaborating with Cellugy to accelerate the development of its innovative platform for producing biofabricated cellulose. This technology will provide a sustainable alternative to fossil-based petrochemicals in various industrial applications, starting with personal care. The new project will ultimately accelerate the understanding and optimization of bacterial cellulose production.

From Ingenza Ltd 30 Aug 2024

Ishani Malhotra named ‘woman entrepreneur of the year’ by cancer research horizons

Cancer Research Horizons, the innovation arm of Cancer Research UK, announced the winners of its second Innovation & Entrepreneurship Awards at it’s gala dinner on the 20th of March in London.These awards celebrate the UK’s most innovative and enterprising efforts in oncology highlighting those individuals in the industry working hard to translate discoveries into benefits for cancer patients.

From Carcinotech 30 Aug 2024

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

Advances in tissue engineering and 3D bioprinting have revolutionized the development of physiologically relevant 3D in vitro cancer models, offering a closer representation of the tumor microenvironment (TME) and enabling high-throughput drug screening.

From Carcinotech 30 Aug 2024

The Arctic Sea revealed as a potential treasure trove for new medicines

Researchers discovered new antivirulence and antibacterial compounds from Arctic marine actinobacteria, offering potential solutions to combat antibiotic-resistant E. coli infections.

30 Aug 2024

Innovative berry-based skin spray targets hospital-acquired bacteria

VTT has developed a skin spray, based on nanocellulose and antimicrobial compounds from wild berries, which can be used to treat wounds and eliminate hospital-acquired bacteria such as MRSA before surgery.

28 Aug 2024

SciY and Allchemy announce strategic distribution agreement

SciY is proud to announce a strategic distribution agreement with Allchemy, a pioneer in Artificial Intelligence (AI) driven drug discovery, co-founded by renowned experts Dr. Sara Szymkuć and Prof. Bartosz Grzybowski.

From SciY 28 Aug 2024

A novel approach to photosynthetic production of high-value compounds

Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucose or glycerol. By engineering photosynthetic cyanobacteria to live symbiotically inside yeast cells, the bacteria-yeast hybrids can produce important hydrocarbons, paving new biotechnical pathways to non-petroleum-based energy, other synthetic biology applications, and the experimental study of evolution.

27 Aug 2024

Octavalent intranasal flu vaccine proves effective in neutralizing both existing and emerging strains

A new octavalent intranasal vaccine shows promising results in providing broad immunity against both seasonal and pre-pandemic influenza strains by eliciting strong mucosal and systemic immune responses in ferrets.

25 Aug 2024

Human gut microbiome: A source of new antibiotic peptides

Researchers identified 323 peptide-based antimicrobials from the human microbiome, with 71% showing significant antibacterial activity, and the lead peptide, prevotellin-2, matching the efficacy of polymyxin B in both in vitro and in vivo models.

25 Aug 2024

AI advances drug discovery for mental health disorders with new receptor models

Artificial intelligence (AI) can help identify molecules that could serve as new drugs for mental health disorders.

23 Aug 2024

Exploring opioid prescription trends in chronic cough treatment

Chronic cough, with symptoms lasting more than eight weeks, affects approximately one in 10 adults. Cough is among the most common reasons for seeking medical care in the United States, yet chronic cough is difficult to treat. One of the largest studies of chronic cough and one of the first to explore the use of opioids, which are known to suppress cough, to treat these patients, has found that 20 percent of patients with chronic cough received a prescription for a cough suppressant containing an opioid.

23 Aug 2024

Novel screening method for blood-brain barrier penetration

Scientists at Southwest Research Institute have developed a new screening method to identify drug formulations that can penetrate the blood-brain barrier (BBB), to facilitate treatment of brain diseases and conditions.

23 Aug 2024

FDA-approved drug could revolutionize organ transplantation

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer's. The team had previously used another drug, SNC80, to achieve similar results in tadpoles and enhance the survival of whole mammalian hearts for transplants, but SNC80 is not approved for clinical use in humans because it can cause seizures. By contrast, DNP is already being used in the clinic, meaning it potentially could be rapidly repurposed for use in emergency situations to prevent irreversible organ injury while a person is being transported to a hospital.

23 Aug 2024