Drug Discovery & Pharmaceuticals

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VUMC and Bayer agree on strategic research alliance to develop new therapies for kidney diseases

Vanderbilt University Medical Center and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development.

12 Sep 2017

Novel compounds found to be highly effective in preventing transmission of malaria parasites

Significant headway has been made in controlling malaria. However, two vexing problems remain: currently available treatments are unable to block transmission of the parasite that causes the disease, and the parasite often becomes resistant to drugs.

7 Sep 2017

Natural compound produced by honeybees could become basis for new antibiotics

An antimicrobial compound made by honeybees could become the basis for new antibiotics, according to new research at the University of Illinois at Chicago.

7 Sep 2017

Researchers synthesizing new, first-in-class drug to stop growth of ER-positive breast cancer

Researchers at UT Health San Antonio and two partner institutions are developing a new, first-in-class agent that has stopped the growth of estrogen receptor-positive (ER-positive) breast cancer in its tracks.

30 Aug 2017

Researchers develop new approach to efficiently produce versatile antibody therapies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy.

29 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Collaborative project reaches milestone halfway point in constructing Kinase Chemogenomic Set

The Structural Genomics Consortium at the University of North Carolina at Chapel Hill (SGC-UNC), in partnership with the DiscoverX Corporation, has reached the milestone halfway point in its development of the Kinase Chemogenomic Set, a potent group of inhibitors which allow deeper exploration of the human kinome, a family of enzymes critical to understanding human disease and developing new therapies.

26 Aug 2017

CSUDH professor seeks novel lead compound to develop new drug for treating cancer

Does anyone have a cardiac pacemaker or medical device implants? How about keys, a mobile phone, or even a wallet? We wouldn't want anything to get damaged or erased."

26 Aug 2017

BioAscent to manage Medivir’s expanding compound library

BioAscent Discovery Limited has taken delivery of Medivir AB’s compound collection of around 56,000 samples, to manage on an outsourced basis.

24 Aug 2017

Study reveals possible medical and industrial properties of avocado seed husks

A new study presented at the 254th National Meeting & Exposition of the American Chemical Society (ACS), suggests that avocado seed husks contain a treasure of unidentified chemical compounds which has the potential to be used in treating various debilitating diseases such as, cancer and heart diseases, as well as in enhancing perfumes, cosmetics and other consumer goods.

22 Aug 2017

New vaccine could offer protection against opioid combinations

Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic.

21 Aug 2017

Stable vaccines using microscopic crystals from cypovirus

Scientists at Cell Guidance Systems, Cambridge University and Imperial College are exploiting microscopic crystals, made by a cypovirus, to produce stable vaccines for diseases that mostly affect the world's poorest people.

From Cell Guidance Systems 21 Aug 2017

Researchers explore if deep-sea sponges could be new source of potential antimicrobials

Marine sponges and the deep-sea ecosystem are comparatively under-studied and under-exploited compared with life in shallower waters - but a team of scientists from the University of Plymouth are identifying and developing potential new antimicrobials produced by the microbiome of sponges which live deep beneath the ocean surface.

17 Aug 2017

Researchers discover synthetic compound effective at relieving neuropathic pain

A team of scientists led by chemists Stephen Martin and James Sahn at The University of Texas at Austin have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway.

17 Aug 2017

Insilico and GSK collaborate to enhance drug discovery process

Insilico Medicine, a Baltimore-based company at the forefront of artificial intelligence (AI) research for drug discovery, biomarker development and aging research announced today that it has formed a collaboration with GSK to explore how Insilico's AI capability can enhance its drug discovery process.

16 Aug 2017

Evidence that cannabis use helps pain or PTSD is lacking, say researchers

Scientific evidence reporting on the use of cannabis for the treatment of chronic pain or post-traumatic stress syndrome (PTSD) is too limited to conclude its safety or efficacy, say researchers from the US Department of Veterans Affairs (VA).

15 Aug 2017

SBIR Fast-Track grant to fund study on new drug that targets cardiovascular diseases

The Exscien Corporation of Louisville, KY, in conjunction with LSU Health New Orleans Cardiovascular Center of Excellence, has been awarded an SBIR Fast-Track grant in the amount of $3.7 million over three years by the National Heart, Lung and Blood Institute.

14 Aug 2017