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Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020

New vaccine for Chikungunya reported safe and well-tolerated

A virus-like particle vaccine was shown to be safe and well-tolerated among a healthy adult population living in chikungunya endemic areas, the researchers report in a new study published in the Journal of the American Medical Association (JAMA).

14 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

Cost of ‘repurposing’ existing drugs to treat COVID-19

The paper looks at repurposed drugs that might demonstrate efficacy against COVID-19, and if they could be manufactured profitably at very low costs to ensure affordable access to vital treatments for COVID-19 at low prices globally.

13 Apr 2020

UChicago Medicine launches clinical trial to explore plasma transfusions for COVID-19 patients

The University of Chicago Medicine is launching a clinical trial to study whether blood plasma from people who have recovered from COVID-19 can be used to treat patients who are still in the hospital with severe disease symptoms.

13 Apr 2020

Intermountain Healthcare and University of Utah Health launch two COVID-19 clinical trials

Researchers from Intermountain Healthcare and University of Utah Health in Salt Lake City have launched two vital clinical trials to test the effectiveness and safety of two drugs - hydroxychloroquine and azithromycin - to treat patients with COVID-19.

13 Apr 2020

Remdesivir shows promise in post-infection treatment for COVID-19 disease

The coronavirus disease (COVID-19) has no approved treatment or vaccine as the world grapple with its wrath. The viral infection has so far infected 1.8 million and killed more than 114,000 people. Now, a team of scientists has shown that an experimental antiviral drug, remdesivir, has shown promise in treating patients with severe COVID-19.

13 Apr 2020

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

After a lightening round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells to block the life-threatening lung inflammation that accompanies severe cases of COVID-19.

11 Apr 2020

Novel clinical trial fast tracks testing of COVID-19 therapies

A novel clinical trial developed by researchers at the University of Pittsburgh School of Medicine launched today at UPMC to address one of the most important debates during the COVID-19 pandemic:

9 Apr 2020

University of Utah Health, Intermountain Healthcare launch two clinical trials to treat COVID-19 patients

Researchers from Intermountain Healthcare and University of Utah Health in Salt Lake City have launched two vital clinical trials to test the effectiveness and safety of two drugs -hydroxychloroquine (HCQ) and azithromycin - to treat patients with COVID-19 (infection with the novel coronavirus).

9 Apr 2020

Clinical trial to investigate effectiveness of antimalarial drugs for COVID-19 treatment

Washington University School of Medicine in St. Louis is launching a clinical trial for patients hospitalized with COVID-19 at Barnes-Jewish Hospital.

9 Apr 2020

Ebola drug now being tested against COVID-19

As the coronavirus pandemic claims lives and overwhelms health care systems throughout the world, scientists are closely watching several late-stage trials of the antiviral drug remdesivir.

8 Apr 2020

Preclinical trials for two coronavirus vaccine candidates commence

Scientists at CSIRO, Australia’s national science body, and the Australian Animal Health Laboratory (AAHL) in Geelong, Victoria, have commenced preclinical trials for two novel coronavirus vaccine candidates.

7 Apr 2020

Bill and Melinda Gates fund potential vaccine against COVID-19

In a race against time, teams of scientists across the world are working towards developing an effective and safe vaccine to prevent infection from the SARS-CoV-2 virus that causes COVID-19 disease.

7 Apr 2020

Antiparasitic drug Ivermectin kills coronavirus in 48 hours

Around the world, scientists race to develop a vaccine or treatment against the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, a team of researchers has found that a drug already available around the world can kill the coronavirus in a lab setting in just 48 hours.

6 Apr 2020

Rush participates in clinical trial to test remdesivir as potential treatment for COVID-19

Rush University Medical Center is participating in a new clinical trial to test the effectiveness of the drug remdesivir in the treatment of coronavirus disease 2019 (COVID-19). This disease currently has no approved treatment.

6 Apr 2020

Penn-led trial to evaluate the effectiveness of HCQ in combating COVID-19 pandemic

A new trial led by the Perelman School of Medicine at the University of Pennsylvania will evaluate whether the drug hydroxychloroquine can benefit people infected with COVID-19, as well as whether taking the drug preventatively may help people avoid infection altogether.

6 Apr 2020

Experimental drug APN01 prevents COVID-19 infection in the lab

With the world gripped with the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a frantic rush to find an effective drug that can be used to treat the disease.

6 Apr 2020

Clinical trial to evaluate experimental COVID-19 drug is underway at Montefiore and Einstein

Montefiore Health System and Albert Einstein College of Medicine has joined a clinical trial to evaluate the experimental drug remdesivir to treat people who are hospitalized with severe COVID-19 infection.

5 Apr 2020

Drug Trial News

Remdesivir drug stops novel coronavirus from replicating

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

New vaccine for Chikungunya reported safe and well-tolerated

Super-charging production of drugs for COVID-19

Cost of ‘repurposing’ existing drugs to treat COVID-19

UChicago Medicine launches clinical trial to explore plasma transfusions for COVID-19 patients

Intermountain Healthcare and University of Utah Health launch two COVID-19 clinical trials

Remdesivir shows promise in post-infection treatment for COVID-19 disease

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

Novel clinical trial fast tracks testing of COVID-19 therapies

University of Utah Health, Intermountain Healthcare launch two clinical trials to treat COVID-19 patients

Clinical trial to investigate effectiveness of antimalarial drugs for COVID-19 treatment

Ebola drug now being tested against COVID-19

Preclinical trials for two coronavirus vaccine candidates commence

Bill and Melinda Gates fund potential vaccine against COVID-19

Antiparasitic drug Ivermectin kills coronavirus in 48 hours

Rush participates in clinical trial to test remdesivir as potential treatment for COVID-19

Penn-led trial to evaluate the effectiveness of HCQ in combating COVID-19 pandemic

Experimental drug APN01 prevents COVID-19 infection in the lab

Clinical trial to evaluate experimental COVID-19 drug is underway at Montefiore and Einstein

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