Drug Trial News

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First patients enrolled in new clinical trial to evaluate potential COVID-19 treatments

Researchers from the University of Oxford have launched a new clinical trial to test the effects of potential drug treatments for patients admitted to hospital with COVID-19. The first patients have now been recruited.

23 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Lopinavir and ritonavir drug combo tested in severe COVID-19

Researchers from China and the United Kingdom have collaborated to conduct a clinical trial looking at the efficacy of a combination of two anti-HIV drugs lopinavir and ritonavir to combat severe cases of COVID-19. Their study titled, “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe COVID-19,” was published in the latest issue of the New England Journal of Medicine (NEJM).

19 Mar 2020

Three-drug combination reduces all-cause mortality in COPD patients

Once-daily treatment of patients with chronic obstructive pulmonary disease (COPD) with an inhaler combining fluticasone furoate (FF), umeclidinium (UMEC) and vilanterol (VI) reduced all-cause mortality by 42 percent, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

18 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

mRNA vaccine against novel coronavirus goes on a trial in Seattle

A clinical trial for a vaccine to protect against the novel coronavirus commenced this Monday in the U.S.. If successful, this could mean an end to the current global pandemic of COVID-19 infections, feel experts.

16 Mar 2020

Potential breakthrough in cancer immunotherapy with gasdermin E

A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present.

11 Mar 2020

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

11 Mar 2020

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

New research reveals bias and stereotyping among clinical and research professionals who recruit patients to enroll in cancer clinical trials. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

10 Mar 2020

How effective is Gabapentin in alcohol use disorder?

A new study published in the journal JAMA Internal Medicine in March 2020 reports the striking efficacy of the drug gabapentin in helping people with alcohol use disorder (AUD) with their alcohol withdrawal symptoms.

9 Mar 2020

The research and development costs of a new drug

Many recent studies have focused on how much it costs to bring a new drug to market in the light of increasing drug prices. Estimates range from $314 million to $2.8 billion. Most of this was based on proprietary data and was, therefore, not verifiable independently, attracting much criticism.

3 Mar 2020

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma

27 Feb 2020

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide long-term benefit for patients.

27 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

Coronavirus vaccine trials commence

The coronavirus disease (COVID-19) outbreak has swept the world, killing 2,770 people and infecting more than 81,000. Amid the health crisis, scientists from across the globe are racing to develop novel therapies and vaccines in the hope of stemming the spread of the deadly virus.

26 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

26 Feb 2020

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

A randomized, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with coronavirus disease 2019 (COVID-19) has begun at the University of Nebraska Medical Center in Omaha.

25 Feb 2020

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.

24 Feb 2020

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

Oncology was the top therapy area for non-industry sponsored clinical trials in 2019, making up 25.7% of all clinical trials.

21 Feb 2020

Drug Trial News

First patients enrolled in new clinical trial to evaluate potential COVID-19 treatments

Immunotherapy treatment shows promise for some patients with advanced rare cancers

Lopinavir and ritonavir drug combo tested in severe COVID-19

Three-drug combination reduces all-cause mortality in COPD patients

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

mRNA vaccine against novel coronavirus goes on a trial in Seattle

Potential breakthrough in cancer immunotherapy with gasdermin E

Newer antiretroviral drugs may be the safest, most effective HIV treatment during pregnancy

Research reveals bias and stereotyping when recruiting patients for oncology clinical trials

How effective is Gabapentin in alcohol use disorder?

The research and development costs of a new drug

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

Chronic cough could be eased with new drug

Coronavirus vaccine trials commence

Investigational drug reduces heartburn severity in patients with refractory GERD

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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