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New study finds almost 400 established medical practices that don’t work

A new study set out to explore what does and does not work in the field of modern medical practice, and came up with 396 reported reversals of previously accepted medical practice over the last few decades.

12 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

Myeloma UK is launching a new research program to continue support for patient-centric myeloma clinical trials in the UK, the UK Myeloma Research Alliance-Myeloma UK-Concept and Access Research Programme.

10 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Clinical trial results reveal that a medication used to treat Alzheimer's disease may also be an effective therapy for individuals addicted to opioids. The findings are published in The American Journal on Addictions.

6 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved medications that modify the disease.

3 Jun 2019

International clinical study of new drug to treat advanced prostate cancers yields promising results

Today the New England Journal of Medicine published the first results of a phase III international clinical study called TITAN (National Clinical Trials Number 02489318), which evaluated the effectiveness and safety of a new drug, apalutamide, to treat advanced prostate cancers.

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Drug therapy may delay onset of myeloma symptoms, finds study

The largest randomized trial involving smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of myeloma symptoms, according to Mayo Clinic researchers.

3 Jun 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia, have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center.

30 May 2019

Research recommends prompt endoscopic removal when children swallow button batteries

Damage to the lining of the stomach can occur quickly when children swallow button batteries; therefore, clinicians should consider prompt endoscopic removal, even when the child is symptom free and the battery has passed safely through the narrow esophagus, according to research presented at Digestive Disease Week® (DDW) 2019.

20 May 2019

New clinical trial to compare effectiveness of injectable drugs and oral medications to treat HIV

Researchers at the University of Colorado Anschutz Medical Campus, working with the National Institutes of Health, will conduct a clinical trial beginning this month to determine if monthly injections of anti-viral drugs are more effective at suppressing the HIV virus than daily pills in a population for whom daily adherence has been a challenge.

10 May 2019

UIC to lead $14.6 million, multi-center COPD research project

The University of Illinois at Chicago will lead a $14.6 million, multi-center research project to determine which of two drugs -- azithromycin, an antibiotic, or roflumilast, an anti-inflammatory medication -- is the most effective at treating chronic obstructive pulmonary disease, which is also known as COPD.

10 May 2019

Drug Trial News

New study finds almost 400 established medical practices that don’t work

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

International clinical study of new drug to treat advanced prostate cancers yields promising results

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Drug therapy may delay onset of myeloma symptoms, finds study

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Research recommends prompt endoscopic removal when children swallow button batteries

New clinical trial to compare effectiveness of injectable drugs and oral medications to treat HIV

UIC to lead $14.6 million, multi-center COPD research project

Study evaluates long-acting HIV therapy in patients unable to adhere to strict daily regimens

Early clinical trial of new treatment for severe dry eye disease shows promising results

New drug successfully lowers levels of toxic protein that causes Huntington disease

NIH-funded trial demonstrates safety of potential treatment in lung transplant patients

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