Genomics

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Cadmium linked to DNA damage and morphological changes caused by particulate matter

Particulate matter causes health problems for those who inhale the fine droplets and particles, but the chemical composition of the mixture matters-;and can vary widely across space and time.

28 Dec 2023

Genetic clue to pericarditis inflammation points to promising new treatments

Sequence variants that protect against pericarditis have been discovered at a genomic locus encoding interleukin-1 immune cytokines.

27 Dec 2023

Study identifies two stem cell types driving jellyfish tentacle growth

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -; but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

25 Dec 2023

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.

22 Dec 2023

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Early embryo DNA replication program reveals unexpected flexibility

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next.

20 Dec 2023

New statistical technique improves disease prediction for people of African descent

A team of scientists from Icahn School of Medicine at Mount Sinai has developed a groundbreaking statistical technique, "BridgePRS," to enhance disease prediction in people of non-European ancestry, particularly those of African descent.

20 Dec 2023

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Scientific advances in the last century have changed our world significantly. For example, the world of genetics has opened doors to a myriad of possibilities: augmented human capabilities, cures for diseases, and even changes to the course of evolution.

19 Dec 2023

Kyoto scientists map double whammy gene clusters for anxiety disorders

Anxiety disorders (ADs) affect more than 280 million people worldwide, making them one of the most common mental health conditions. ADs have a genetic basis as seen from inheritance in families, and people with one subtype of AD tend to have another subtype, suggesting a shared genetic basis.

19 Dec 2023

From Neanderthals to now: Tracing the evolution of human sleep cycles

Researchers examined the differences in circadian biology between the ancestors of modern humans and the archaic hominins such as Denisovans and Neanderthals and the contribution of archaic introgression in human chronotypes by using genomes to trace chronotype evolution from archaic hominins to modern-day humans.

19 Dec 2023

Decoding the genome of world's biggest bacteria

Not all bacteria are created equal. Most are single-celled and tiny, a few ten-thousandths of a centimeter long. But bacteria of the Epulopiscium family are large enough to be seen with the naked eye and 1 million times the volume of their better-known cousins, E. coli.

18 Dec 2023

How exercise battles muscle fat: New gene holds the answer

Myosteatosis, or aging-related fat accumulation in skeletal muscles, is a leading cause of declines in muscle strength and quality of life in elderly adults.

18 Dec 2023

Scientists identify genetic and epigenetic culprits behind bilateral Wilms tumor

Children with bilateral Wilms tumor have a tumor in each of their kidneys -; a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease.

18 Dec 2023

Scientists crack the code for targeting cancer's 'death star' protein

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS.

18 Dec 2023

Chia genome sequenced, revealing potential health benefits

In a recent study published in Frontiers in Plant Science, researchers presented the assembly of the chia reference genome.

18 Dec 2023

Spatial and subtype-specific regulation of ribosomal RNA genes in Arabidopsis revealed

Arabidopsis thaliana is a species grown worldwide for genetic research and was the first plant to have its complete set of chromosomes (its genome) sequenced.

15 Dec 2023

Study tracks evolution of deadly chicken virus using ancient DNA

An international team of scientists led by geneticists and disease biologists from the University of Oxford and LMU Munich have used ancient DNA to trace the evolution of Marek's Disease Virus (MDV).

15 Dec 2023

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

A new LMU-led DFG Research Unit is developing innovative approaches for treating retinal diseases.

15 Dec 2023

Study uncovers vast genomic diversity in Aboriginal Australian communities

Study on Aboriginal Australian communities using whole-genome sequencing reveals a high level of unique genetic diversity, including novel alleles and structural variants, crucial for understanding human genomic evolution and medical genetics.

14 Dec 2023

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Genome-wide association studies (GWAS) on patient blood samples are useful for identifying the genetic basis of blood cell traits and their links to common diseases.

14 Dec 2023

Genomics

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Genetic clue to pericarditis inflammation points to promising new treatments

Study identifies two stem cell types driving jellyfish tentacle growth

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

UW-Madison technology unveils autism gene's impact on early brain structure

Early embryo DNA replication program reveals unexpected flexibility

New statistical technique improves disease prediction for people of African descent

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Kyoto scientists map double whammy gene clusters for anxiety disorders

From Neanderthals to now: Tracing the evolution of human sleep cycles

Decoding the genome of world's biggest bacteria

How exercise battles muscle fat: New gene holds the answer

Scientists identify genetic and epigenetic culprits behind bilateral Wilms tumor

Scientists crack the code for targeting cancer's 'death star' protein

Chia genome sequenced, revealing potential health benefits

Spatial and subtype-specific regulation of ribosomal RNA genes in Arabidopsis revealed

Study tracks evolution of deadly chicken virus using ancient DNA

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

Study uncovers vast genomic diversity in Aboriginal Australian communities

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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