Genomics

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Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers identify an association between the C-reactive protein gene variant rs1205 and COVID-19 severity.

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

How complementarity-determining region (CDR) loops in the single-chain variable fragment (scFv) influence chimeric antigen receptor (CAR)-T cell behavior.

14 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Study reveals the genetics of hair whorl direction

The first gene mapping study on human scalp hair whorls not only shows that hair whorl direction has a genetic basis, but also that it is affected by multiple genes.

9 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

Effect of mutations in cancer-driving genes across human cancers

Effect of mutations in cancer-driving genes across human cancers.

9 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

Unexpected link between pure mathematics and genetics discovered

An interdisciplinary team of mathematicians, engineers, physicists, and medical scientists have uncovered an unexpected link between pure mathematics and genetics, that reveals key insights into the structure of neutral mutations and the evolution of organisms.

8 Aug 2023

Genome editing in the spotlight: genetic disorder carriers' views shape the conversation

Study explores perspectives on the applications of somatic genome editing.

8 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

How does the circulating proteome influence brain health?

Researchers investigate the association between the circulating proteome and brain health.

7 Aug 2023

Genetic reasons behind Raynaud's phenomenon discovered

Researchers at Queen Mary University of London's Precision Healthcare Research Institute (PHURI) and the Berlin Institute of Health (BIH) at Charité – Universitätsmedizin Berlin have identified the genetic causes of Raynaud's phenomenon.

4 Aug 2023

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression.

4 Aug 2023

GEMINI test shows promise for early detection of lung cancer

Novel blood testing technology being developed by researchers at the Johns Hopkins Kimmel Cancer Center that combines genome-wide sequencing of single molecules of DNA shed from tumors and machine learning may allow earlier detection of lung and other cancers.

4 Aug 2023

Study uncovers the science behind the body's tanning process after leaving the beach

Beachgoers are familiar with the experience of spending hours in the sun, going home, and noticing only hours later that their skin has changed color.

3 Aug 2023

Genomics

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Mice lacking TMCO3 gene have shortened bones

Study reveals the genetics of hair whorl direction

What are some recent advancements in proteomics-driven pancreatic oncology research?

Effect of mutations in cancer-driving genes across human cancers

The impact of epigenetic features on breast cancer treatment and outcomes

NLRP3 inflammasome plays a role in podocyte aging

Unexpected link between pure mathematics and genetics discovered

Genome editing in the spotlight: genetic disorder carriers' views shape the conversation

Similarities in gene expression between post-mortem and living human brains

How does the circulating proteome influence brain health?

Genetic reasons behind Raynaud's phenomenon discovered

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

GEMINI test shows promise for early detection of lung cancer

Study uncovers the science behind the body's tanning process after leaving the beach

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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