Genomics

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MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI, a company committed to building core tools and technology to lead life science, announced the signing of a licensing agreement with Xpress Genomics, a leading Stockholm-based company specializing in automated and scalable RNA-sequencing strategies.

From MGI 16 Jun 2023

Penn research bolsters scientific understanding behind why some people are more prone to allergies

New research is bolstering scientific understanding behind why some people are more prone to allergies than others.

15 Jun 2023

Innovative method to map specific DNA markings could be used for early cancer detection

Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and have key roles in health and disease.

15 Jun 2023

COVID-19 susceptibility mechanism discovered using a newly created tool

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify genes and molecular pathways associated with disease risk that have previously been too complex to detect or interpret.

15 Jun 2023

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

Science China Life Sciences magazine recently reported on the research results of Tang Beisha's team from Xiangya Hospital of Central South University, Liu Jing Yu's team from the Institute of Neurology of the Chinese Academy of Sciences, and Zhang Luoying's team from Huazhong University of Science and Technology, including Du Shiyue, Zeng Sheng, and Song Li. Epilepsy has a complex etiology with 80% owing a genetic basis.

15 Jun 2023

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

CrossDome tool helps predict the potential risks of T-cell immunotherapy

Researchers at the University of Houston are working to make T-cell immunotherapy safer, developing a tool called CrossDome, which uses a combination of genetic and biochemical information to predict if T-cell immunotherapies might mistakenly attack healthy cells.

14 Jun 2023

Scientists show how pregnancy induces progressive changes in the maternal immune system

We have a good understanding of how a woman's external features can change during pregnancy, but scientists know surprisingly little about what biological changes occur internally.

13 Jun 2023

Heat-damaged DNA in food may contribute to genetic risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

13 Jun 2023

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

University of California, Irvine neuroscientists probing the gene changes behind Alzheimer's disease have developed a process of making a "meta-cell" that overcomes the challenges of studying a single cell.

13 Jun 2023

Study shows link between death perception and reduced aging in flies

Researchers led by Christi Gendron at the University of Michigan, US, have found the link between death perception and reduced aging in flies.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

Tracing the ancestry of hybrids using a new method

If you've ever kept a garden, you're probably familiar with hybrids, from disease-resistant tomatoes to Stargazer lilies.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Researchers identify microRNAs associated with a weakened immune response to COVID-19

A team of researchers at NYU Abu Dhabi, led by Associate Professor of Biology Youssef Idaghdour and working in collaboration with clinicians at several Abu Dhabi hospitals, investigated the association between microRNAs, a class of small RNA molecules that regulate genes, and COVID-19 severity among 259 unvaccinated COVID-19 patients living in Abu Dhabi.

11 Jun 2023

Genomics

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

Penn research bolsters scientific understanding behind why some people are more prone to allergies

Innovative method to map specific DNA markings could be used for early cancer detection

COVID-19 susceptibility mechanism discovered using a newly created tool

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

CrossDome tool helps predict the potential risks of T-cell immunotherapy

Scientists show how pregnancy induces progressive changes in the maternal immune system

Heat-damaged DNA in food may contribute to genetic risks

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Study shows link between death perception and reduced aging in flies

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Tracing the ancestry of hybrids using a new method

ACMG publishes updated recommendations for CFTR carrier screening

"Homing gene drive system" could help suppress agricultural pests

Researchers identify microRNAs associated with a weakened immune response to COVID-19

Genetic counselling for familial colorectal cancer provides improves patients' feelings of empowerment

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

AI system in eye scans enables better diagnosis of inherited retinal diseases

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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