Genomics

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Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Genes required for complex behaviors originated around 650 million years ago

A team of scientists led by researchers from the University of Leicester have discovered that the genes required for learning, memory, aggression and other complex behaviors originated around 650 million years ago.

14 Jul 2023

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome sequencing technology Stereo-seq and snRNA-seq technology, which provides a molecular and cellular basis for further investigation into neural circuits.

14 Jul 2023

INTEGRA pipetting solutions accelerate crucial viral genomics research

The Center for Emerging Viral Threats (CEVT) in Louisiana, USA, is using INTEGRA Biosciences’ liquid handling solutions for COVID-19 testing and viral genomics studies.

From INTEGRA Biosciences 14 Jul 2023

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Researchers investigate the relationship between the gut microbiome, physical fitness, and epigenetic aging in physically fit individuals.

14 Jul 2023

Cryo-EM reveals structure of key enzyme involved in protein production

Transfer RNAs (tRNAs) are among the most common types of RNA in a cell and are indispensable for protein production in all known organisms.

13 Jul 2023

Using CRISPR gene-editing system to build a more sustainable forest

Researchers at North Carolina State University used a CRISPR gene-editing system to breed poplar trees with reduced levels of lignin, the major barrier to sustainable production of wood fibers, while improving their wood properties.

13 Jul 2023

New heart cell atlas reveals detailed structure of the human heart

In a new study, published today (12 July) in Nature, researchers have produced the most detailed and comprehensive human Heart Cell Atlas to date, including the specialised tissue of the cardiac conduction system - where the heartbeat originates.

12 Jul 2023

Scientists track nanoscale processes of CRISPR-Cas complexes

Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within milliseconds.

12 Jul 2023

Retrotransposons hijack cell's dna repair machinery to form circular DNA

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell's own machinery to achieve its goals.

12 Jul 2023

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

11 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023

Same-sex sexual behavior may be a common feature of primate reproduction, study suggests

Observations of a wild colony of macaques over three years show same-sex sexual behavior among males is widespread and may be beneficial.

10 Jul 2023

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced that Bioscientia is using its Revio long-read sequencing system to expand its genomics research projects and sequence several thousand human genomes per year.

10 Jul 2023

Researchers identify and characterize a key negative regulator of shoot regeneration in Arabidopsis

Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction.

7 Jul 2023

Living digital camera: scientists capture light patterns in DNA for image storage

Researchers described a technique of capturing two-dimensional (2D) light patterns into DNA.

6 Jul 2023

Novel workflow reveals untapped diversity in fatty acid isomers across all life forms

Researchers introduced a comprehensive workflow to discover unsaturated fatty acids (FA).

6 Jul 2023

New CRISPR-based system could eliminate malaria-carrying mosquitoes

Malaria remains one of the world's deadliest diseases. Each year malaria infections result in hundreds of thousands of deaths, with the majority of fatalities occurring in children under five.

5 Jul 2023

Candidate genes for inflammatory bowel disease identified

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife.

5 Jul 2023

Robotic system may accelerate studies in diverse areas of C. elegans biology

A robotic system capable of imaging and transferring the model organism Caenorhabditis elegans could replace hours of tedious lab work, according to a recent study.

5 Jul 2023

Genomics

Aerobic glycolysis essential for eye development in mammals, study finds

Genes required for complex behaviors originated around 650 million years ago

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

INTEGRA pipetting solutions accelerate crucial viral genomics research

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Cryo-EM reveals structure of key enzyme involved in protein production

Using CRISPR gene-editing system to build a more sustainable forest

New heart cell atlas reveals detailed structure of the human heart

Scientists track nanoscale processes of CRISPR-Cas complexes

Retrotransposons hijack cell's dna repair machinery to form circular DNA

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

Same-sex sexual behavior may be a common feature of primate reproduction, study suggests

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

Researchers identify and characterize a key negative regulator of shoot regeneration in Arabidopsis

Living digital camera: scientists capture light patterns in DNA for image storage

Novel workflow reveals untapped diversity in fatty acid isomers across all life forms

New CRISPR-based system could eliminate malaria-carrying mosquitoes

Candidate genes for inflammatory bowel disease identified

Robotic system may accelerate studies in diverse areas of C. elegans biology

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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