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Tirzepatide cuts diabetes risk by 90% in obese patients, study shows

Tirzepatide, a new injectable weight-loss drug with the trade name Zepbound, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, Yale School of Medicine and other institutions.

26 Nov 2024

Genetic factors drive early onset and complications of type 2 diabetes in British Asians

A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people.

26 Nov 2024

Researchers explore the impact of primary progressive aphasia on quality of life

Imagine gradually losing the ability to express yourself - not because you've forgotten the words, but because they simply won't come out.

26 Nov 2024

Lower pulmonary gas exchange may be linked to impaired cognitive function in long COVID patients

In patients with long COVID, lower pulmonary gas exchange may be associated with impaired cognitive function, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2024

Specific protein patterns can predict IBD up to 16 years before diagnosis

Scientists at örebro University have identified specific protein patterns in blood that can predict inflammatory bowel disease (IBD) up to 16 years before diagnosis.

26 Nov 2024

Study reveals how cancer cells evade chemotherapy in low-glucose environments

Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new study shows.

26 Nov 2024

Study shows cancers are uniformly growing masses

Researchers at the University of Cologne and the Centre for Genomic Regulation (CRG) in Barcelona have discovered that cancer grows uniformly throughout its mass, rather than at the outer edges.

26 Nov 2024

Research shows impact of concussions on aperiodic brain activity

A new study of high school football players found that concussions affect an often-overlooked but important brain signal.

26 Nov 2024

University of Oklahoma professor honored with prestigious Palade Prize for pancreatic cancer research

Min Li, Ph.D., a George Lynn Cross Professor of Medicine, Surgery and Cell Biology at the University of Oklahoma College of Medicine and Associate Director for Global Oncology at OU Health Stephenson Cancer Center, will receive the 2024 Palade Prize from the International Association of Pancreatology.

26 Nov 2024

The role of emotion regulation in predicting suicidal risk in depressed individuals

Depressed individuals who reflexively attempt to dampen their initial emotional responses to reminders of their negative memories have a low tolerance for distressing emotional stimuli in general and may respond to stress in their daily lives with greater upticks in suicidal thoughts.

26 Nov 2024

Study unlocks the secrets of beta cell regeneration

Prof. Heiko Lickert is the director of the Institute of Diabetes and Regeneration Research at Helmholtz Munich, professor at the Technical University of Munich (TUM), and member of the German Center for Diabetes Research (DZD).

26 Nov 2024

Nasal spray shows promise in combating Alzheimer's

A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease.

26 Nov 2024

A prospective study of antibiotic use and clinical factors in patients with suspected pneumonia

This study explored how chest X-ray results influence antibiotic initiation by general practitioners in France when managing patients with suspected pneumonia.

26 Nov 2024

Hormone therapy in early menopause proves safe but lacks cognitive benefits

Early menopausal hormone therapy neither benefits nor harms long-term cognition, offering reassurance but no protection against cognitive decline in healthy women.

26 Nov 2024

GLP-1 receptor agonists prove effective for kidney and cardiovascular outcomes

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.

25 Nov 2024

New funding expands study of brain changes in bipolar disorder

Leila Nabulsi, PhD, a postdoctoral researcher in computational neuroscience at the Keck School of Medicine of USC's Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has received funding to expand research on the neurocircuitry that underlies bipolar disorder.

25 Nov 2024

Revolutionary strategy offers hope for type 1 diabetes treatment

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant.

25 Nov 2024

How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

Addressing the challenges of cognitive impairment detection in primary care

Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. This special report summarizes key points and gaps in knowledge about methods for detecting cognitive impairment in primary care clinics.

25 Nov 2024

Peer support program shows promise for cancer patients in Vietnam

Having cancer can be one of the most physically and emotionally draining experiences of a person's life, but navigating this disease without adequate support or resources makes this journey even more burdensome.

25 Nov 2024