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GLP-1RAs show added protection against cancer beyond weight reduction

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.

11 May 2025

Scientists link specific gene variants to post-vaccine myocarditis and pericarditis

A genome-wide association study in Sweden identified rare genetic variants near the SCAF11 and LRRC4C genes that may be linked to heart inflammation following COVID-19 mRNA vaccination. The findings shed light on potential biological pathways driving vaccine-associated myocarditis and pericarditis, particularly among younger individuals.

11 May 2025

Vegetarians may need to watch thyroid health, especially with low iodine intake

Vegetarians had a modestly higher risk of developing hypothyroidism compared to high meat-eaters, but only after adjusting for BMI. No increased risk was seen for vegans or pescatarians in incident cases, though pescatarians showed a slight increase in baseline prevalence.

11 May 2025

Woman with rare genetic disorder delivers healthy baby after complex pregnancy

When Jessica Johnson, 36, began to experience labored breathing and heart palpitations, she quickly made an appointment to see a cardiologist.

11 May 2025

Time-restricted eating may be a promising strategy for sustaining long-term weight loss

Three months of time-restricted eating (TRE), irrespective of whether it is earlier or later in the day, may be a promising strategy for sustaining long-term weight loss in adults with overweight or obesity, according to preliminary results of a randomised controlled trial being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Multimodal AI system improves lung cancer screening accuracy

Lung cancer is one of the most challenging diseases, making early diagnosis crucial for effective treatment.

11 May 2025

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can lead to significant weight loss and improve blood sugar control in adults with severe mental illness, as well as having positive effects on mood, well-being, and quality of life in those both with and without mental illness, according to a systematic review of the available evidence being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Sumeet Chugh named vice dean and chief artificial intelligence health research officer at Cedars-Sinai

Sumeet Chugh, MD, whose research into sudden cardiac arrest has led to novel methods of predicting the usually fatal condition, has been promoted to vice dean and chief artificial intelligence health research officer at Cedars-Sinai.

11 May 2025

Long term steroid use raises risk of adrenal insufficiency

Individuals taking steroid tablets for more than 3 months are over 6 times more likely to be diagnosed with adrenal insufficiency than those treated with non-steroidal anti-inflammatory drugs, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Newly identified gene mutation causes severe form of Fanconi anemia

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening.

11 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Delayed puberty in boys raises risk of type 2 diabetes later in life, study shows

A large Israeli study found that boys who experience delayed puberty are significantly more likely to develop type 2 diabetes in early adulthood. This increased risk persists even after accounting for body weight, socio-economic status, and other confounding factors.

10 May 2025

Maternal testosterone levels shape boys' activity and girls' strength by age 7

Boys born to mothers with PCOS or high third-trimester testosterone levels are less physically active at age 7, particularly on weekends. Girls exposed to high prenatal testosterone show reduced muscle strength but not lower activity levels.

10 May 2025

Obesity in teens alters brain regions tied to memory and emotion

Adolescents with abdominal obesity have larger brain regions linked to memory and emotional control, potentially due to inflammation, according to a large MRI-based study. These brain changes, coupled with socioeconomic disadvantage, may impair cognitive and emotional development during adolescence.

10 May 2025

Study reveals phthalate exposure harms early sexual development in children

Maternal exposure to phthalates during pregnancy is linked to shorter anogenital distance in 3-year-old boys, a marker of impaired sexual development. Girls showed similar outcomes from their own postnatal exposure, highlighting the lasting hormonal risks of environmental pollutants.

10 May 2025

Antibiotic use in infancy raises early puberty risk in girls, study finds

Girls exposed to antibiotics in the first three months of life are significantly more likely to enter puberty early, according to a large South Korean study. The risk increases with earlier exposure and a greater number of antibiotic classes, with no similar effect seen in boys.

10 May 2025

Mothers' early pregnancy weight influences kids’ BMI into adolescence

Children born to mothers with higher BMI in early pregnancy have greater weight and BMI from birth through age 10, regardless of prenatal lifestyle interventions. Paternal BMI also plays a significant role in childhood obesity risk.

10 May 2025

KL-6 levels help differentiate interstitial lung disease from abnormalities

Krebs von den Lungen-6 (KL-6), predominantly expressed by type II alveolar cells, is linked to the prognosis and severity of interstitial lung disease (ILD).

10 May 2025