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Gut microbiome found to play key role in chronic disease progression

The gut microbiome, an ecosystem of trillions of microorganisms in the human digestive tract, has been increasingly linked to chronic diseases.

15 Nov 2024

Obesity crisis in the U.S. expected to worsen by 2050

Over the past three decades, there has been a startling increase in the prevalence of obesity across the USA, at least doubling in adult men and women (aged 25 and older) and older female and male adolescents (aged 15-24 years) since 1990, with the number of people living with overweight and obesity reaching over 208 million in 2021 - a trend set to continue in the coming decades without significant reform, according to a major new analysis from the Global Burden of Disease Study Collaborator Network, published in The Lancet.

15 Nov 2024

Rare STAT6 gene variant provides protection against severe asthma

Scientists at deCODE genetics, a subsidiary of Amgen, and collaborators have published a study in Journal of Allergy and Clinical Immunology reporting a rare missense variant in STAT6 that protects against asthma.

15 Nov 2024

Duke-NUS team develops test to monitor engineered T cells in cancer treatment

A novel test developed by Duke-NUS researchers enables real-time monitoring of T cells that have been engineered to fight cancer, after re-introduction into the body of a cancer patient.

15 Nov 2024

International team releases recommendations for AI use in neuro-oncology

An international, multidisciplinary team of leading neuro-oncology researchers and clinicians has released new recommendations for good clinical practice - a set of guidelines that helps ensure clinical trial results are reliable, and patients are protected - regarding the use of artificial intelligence methods to more accurately diagnose, monitor and treat brain cancer patients.

15 Nov 2024

Computer-assisted CBT and mental health apps effective in reducing anxiety, depression symptoms

Computer-assisted cognitive-behavior therapy (CCBT) and mobile mental health applications warrant continued development and ongoing efforts to increase acceptance among patients and clinicians, according to a review published in the Journal of Psychiatric Practice, part of the Lippincott portfolio from Wolters Kluwer.

15 Nov 2024

Breakthrough in protein engineering may lead to more effective cancer therapies

Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments.

15 Nov 2024

Customizable biological sensors activate cancer immunotherapy only in tumor environments

Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells.

15 Nov 2024

Nanowire-based technology detects cancer-associated miRNAs in urine

Cancer has a high death rate with delayed diagnosis of the disease being one of the main reasons for its fatality.

15 Nov 2024

Study focuses on COPD progression in younger populations

Researchers are exploring how small airway abnormalities in younger smokers could help identify who is at risk of developing COPD and establish how the chronic lung disease progresses, according to a new article.

15 Nov 2024

Study reveals high-resolution structure of blood pressure-regulating receptor

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better drug targeting of the receptor for diseases like hypertension and heart failure.

15 Nov 2024

Largest ALS patient-based iPSC repository opens new frontiers in research

In a landmark continuing collaboration, Answer ALS and Cedars-Sinai have announced the completed availability of the largest amyotrophic lateral sclerosis (ALS) patient-based induced pluripotent stem cell (iPSC) and bio data repository.

15 Nov 2024

Global gap in diabetes prevalence and treatment has widened since 1990

Global diabetes rates have surged, particularly in low-resource areas, revealing critical gaps in treatment access and highlighting the need for improved care.

15 Nov 2024

Air pollution linked to head and neck cancer risk

Increased PM2.5 levels are linked to higher head and neck cancer risk, particularly in disadvantaged communities, highlighting urgent public health measures.

15 Nov 2024

Cognitive behavioral therapy shows promise for prolonged grief disorder

Integrative cognitive behavioral therapy shows greater efficacy than present-centered therapy in reducing grief severity and comorbid symptoms after treatment.

15 Nov 2024

Inequalities in green space linked to preventable deaths in urban areas

Findings reveal that more green space in deprived neighborhoods is associated with lower mortality rates, advocating for strategic public health initiatives.

15 Nov 2024

Argonne receives $21.7 million to advance cancer and vaccine discoveries

The U.S. Department of Energy's (DOE) Argonne National Laboratory will use its world-leading capabilities in artificial intelligence (AI) and high performance computing to research novel ways to fight cancer and transform vaccine discovery.

15 Nov 2024

AI-powered tool predicts gene activity in cancer cells from biopsy images

To determine the type and severity of a cancer, pathologists typically analyze thin slices of a tumor biopsy under a microscope.

14 Nov 2024

Researchers use cerebrospinal fluid to unlock pathways in Alzheimer's disease

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box though, in part because of the challenges of examining in molecular detail the brain of a living patient.

14 Nov 2024

Female firefighters face elevated breast cancer risks due to toxic exposures

It's well documented that firefighters have significantly higher rates of cancer than the general population, and these elevated rates have been associated with exposures to toxic chemicals on the job.

14 Nov 2024