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Exploring the dual role of LKB1 in tumor suppression and promotion

Mutations in serine-threonine kinase 11 (STK11) and liver kinase B1 (LKB1) are associated with disease progression in Peutz-Jeghers syndrome (PJS), which can progress to cancer.

22 Feb 2025

CT scans expose widespread health problems in Viking skulls

Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more.

22 Feb 2025

Development of lymphoma following CAR-T cell therapy

Some forms of blood cancer, such as multiple myeloma and lymphoma, are malignant diseases that originate from immune cells, specifically lymphocytes.

22 Feb 2025

AI-driven discovery unveils TNIK inhibition as anti-aging strategy

A groundbreaking study led by researchers at Insilico Medicine has revealed the potential of TNIK inhibition as an innovative anti-aging strategy.

22 Feb 2025

Study finds lack of consensus on how to treat chronic non-cancer pain

Chronic pain is complex and difficult to treat. Prescribing opioid pain medications has become controversial but may help some patients.

22 Feb 2025

Doctors speaking the patient's language linked to lower cardiovascular disease risk

A positive patient-doctor relationship is an ingredient to a healthy life, and new research has zeroed in on the impact common language in the relationship can have by decreasing cardiovascular disease for the benefit of a longer life.

21 Feb 2025

Engineered blood vessel cells boost islet transplant success in diabetes treatment

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine investigators.

21 Feb 2025

Targeted mRNA therapy shows promise for healing damaged lungs

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

21 Feb 2025

FDA-approved devices used to treat cardiovascular diseases

Heart disease, also called cardiovascular disease, can have serious consequences. It's the leading cause of death for adults in the U.S. Medical devices approved by the U.S. Food and Drug Administration, such as pacemakers and defibrillators, have extended and improved the lives of millions of people living with heart disease.

21 Feb 2025

Kennesaw State researcher wins prestigious award for heart disease diagnostic innovation

Kennesaw State University researcher Chen Zhao has earned the 2025 American Heart Association Institutional Research Enhancement Award (AIREA) for his unique research on non-invasive blood flow prediction in cardiovascular disease diagnosis.

21 Feb 2025

Characterizing the spectrum of mitochondrial DNA deletion disease syndromes

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA deletion disease syndromes.

21 Feb 2025

Targeting FGFR mutations offers new hope for bone repair in skeletal disorders

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect craniofacial and mandibular development.

21 Feb 2025

New guidelines allow select athletes with heart abnormalities to participate in competitive sports

Recent research suggests that select athletes with cardiovascular abnormalities may be able to safely participate in competitive sports after shared decision-making with their clinicians about potential risks, according to a joint scientific statement published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in JACC, the flagship journal of the American College of Cardiology.

21 Feb 2025

Exploring EGCG's role in protecting against acetaminophen-induced liver injury

Announcing a new publication for Acta Materia Medica journal. Excessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote.

21 Feb 2025

New 3D tissue imaging technique enhances thyroid tumor analysis

Empa researchers have developed a new 3D tissue analysis for thyroid tumors. This special X-ray technique uses artificial intelligence to enable faster and more precise diagnoses.

21 Feb 2025

Researchers highlight limited use of valuable screening tools for Alzheimer’s and other dementias

Despite the potential benefits of early detection and increasing treatment options for Alzheimer’s disease and related dementias, there is limited use of valuable screening and testing tools, say researchers at the University of Michigan.

21 Feb 2025

The dangers of fraudulent diabetes products and how to avoid them

As the number of people diagnosed with diabetes continues to grow, an increasing number of products marketed under the guise of "dietary supplements" or "over-the-counter drugs" promising to prevent, treat, and even cure diabetes are being sold illegally.

21 Feb 2025