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High body roundness index linked to increased cardiovascular disease risk

Having a high body roundness index (BRI) over a 6-year period was associated with an increased risk of developing cardiovascular disease for adults older than age 45, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

25 Sep 2024

Higher doses of buprenorphine linked to lower emergency visits in opioid use disorder

Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to an analysis funded by the National Institutes of Health (NIH).

25 Sep 2024

International research initiative aims to improve cardiovascular care for women

The American Heart Association, celebrating 100 years of lifesaving service as the world's leading nonprofit organization focused on heart and brain health for all, is joining with other top cardiovascular research funders around the world to support an international scientific research grant focused on women's cardiovascular health.

25 Sep 2024

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

25 Sep 2024

Combining treatments to boost tumor response in lung cancer

Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.

25 Sep 2024

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke.

25 Sep 2024

Deadly high blood pressure during pregnancy is on the rise

Sara McGinnis was pregnant with her second child and something felt off. Her body was swollen. She was tired and dizzy.

25 Sep 2024

One-third of former professional American football players report a punch-drunk reality - CTE

Study found that one-third of former American football players reported perceived CTE, which was significantly associated with a higher risk of suicidality and mental health problems.

25 Sep 2024

Women remain underserved in cardiovascular disease treatment despite advances

Women in the UK, and elsewhere, are still missing out on vital treatment for their No 1 killer - cardiovascular disease - despite significant progress in the medical management of heart disease and stroke, concludes a consensus statement published online in the journal Heart.

24 Sep 2024

Research uncovers mechanism of psychedelic-induced anxiety reduction

A classic psychedelic, similar to LSD, psilocybin and mescalin, was found to activate a cell type in the brain that silences other neighboring neurons, a result that provides insight into how such drugs reduce anxiety, according to a new study.

24 Sep 2024

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) focused Broad Agency Announcement (BAA) contract from the U.S. Food and Drug Administration (FDA).

24 Sep 2024

Semaglutide shows promise in treating chronic skin condition in obese patients

A pioneering study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, demonstrates the significant potential of semaglutide in treating hidradenitis suppurative (HS), a common and chronic skin condition, in people with obesity.

24 Sep 2024

Targeted obesity programs reduce lipid-related heart disease risk in children

Researchers assess the lipid profiles of obese children and adolescents and their health implications.

24 Sep 2024

Study uncovers decision-making impairments linked to Parkinson's drug

Parkinson's disease (PD), also known simply as Parkinson's, is a disorder of the nervous system that affects millions of people worldwide.

24 Sep 2024

Study reveals limited access to opioid treatment in US jails

A new look into addiction treatment availability in the U.S. criminal justice system reveals that fewer than half (43.8%) of 1,028 jails surveyed across the nation offered any form of medication for opioid use disorder, and only 12.8% made these available to anyone with the disorder.

24 Sep 2024

New guidelines for cardiovascular management in noncardiac surgery released

The 2024 guideline for cardiovascular management of adults undergoing noncardiac surgery reflects a decade of updates and new evidence since the guideline's last release in 2014.

24 Sep 2024

Study shows little rebound in cancer diagnoses post-pandemic

Cancer incidence trends in 2021 largely returned to what they were before the COVID-19 pandemic, according to a study by researchers at the National Institutes of Health (NIH).

24 Sep 2024

Innovative ALS study receives $22 million grant for experimental drug

Mayo Clinic in Florida has received a grant from the National Institute of Neurological Disorders and Stroke (NIDS) to begin an innovative study that will provide hundreds of patients with amyotrophic lateral sclerosis (ALS) access to the experimental drug ibudilast over six months.

24 Sep 2024

Study finds nearly 200 potential breast carcinogens in food contact materials

Research identifies nearly 200 potential breast carcinogens in food contact materials, including plastics and paper, highlighting widespread exposure despite existing regulation.

24 Sep 2024

Neurostimulation target identified for treating PTSD in veterans

A new study led by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that using neurostimulation therapies on a specific brain network could treat post traumatic stress disorder (PTSD) in veterans.

24 Sep 2024