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University of Oklahoma researcher leads efforts to unravel mysteries of cognitive decline

An estimated 76,000 Oklahomans are living with Alzheimer's disease, a number that has surged by 13% in just five years. Yet, despite the increasing need for effective treatments, therapies for age-related dementia have largely failed to slow or halt the disease's progression.

29 Jan 2025

Climate change is pushing up rates of kidney disease and urological cancers

Climate change is increasing the risk of urological diseases, including cancer and kidney conditions, while urological healthcare itself contributes to environmental harm through high carbon emissions.

29 Jan 2025

Survey shows more Americans prepared to perform CPR in cardiac emergencies

When someone's heart stops pumping, early CPR can save their life. New survey research from the American Heart Association reveals more Americans are prepared to provide that lifesaving rhythm for their friends, family and community.

29 Jan 2025

Research highlights differences in how hospitals diagnose appendicitis in children

Abdominal pain is among the most common reasons children are taken to the emergency department.

29 Jan 2025

Study reveals strong link between childhood trauma and adolescent psychiatric disorders

A new study by a team of researchers from the UK and Brazil has revealed a strong connection between childhood trauma and the development of psychiatric disorders in adolescents living in low-and middle-income countries.

29 Jan 2025

Chiropractic spinal manipulation reduces opioid risks for sciatica patients

A new study led by researchers at University Hospitals Connor Whole Health found that adults with newly diagnosed sciatica who initially received chiropractic spinal manipulation (CSM) were significantly less likely to experience opioid-related adverse drug events (ORADEs) such as overdose and poisoning over a one-year follow-up compared to those receiving usual medical care.

29 Jan 2025

Fluctuating cholesterol linked to higher risk of dementia in older adults

Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jan 2025

From gut health to metabolism: How sleep controls more than you think

Study reveals that sleep traits predict over 15% of body characteristics across 15 physiological systems, with visceral fat, cardiovascular health, and metabolism deeply intertwined with sleep patterns.

29 Jan 2025

Weekly diabetes injection could replace daily shots for lipodystrophy patients

Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves patients with almost zero fat tissue, according to a study in The New England Journal of Medicine.

29 Jan 2025

Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

Can an online lifestyle plan keep your brain sharp? Research says yes

"Maintain Your Brain" study shows how a tailored online program can improve cognition and lower dementia risk—discover how simple lifestyle changes could protect your brain as you age.

29 Jan 2025

Study identifies potential gain of function mutation in retinoblastoma

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation."

29 Jan 2025

Researchers propose personalized probiotic therapies for inflammatory diseases

A new approach to treating inflammatory diseases through personalized probiotic therapies – also known as precision medicine – has been proposed by researchers at the University of Surrey.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Exploring the interaction between cell death and cellular senescence in cancer

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

29 Jan 2025

Study aims to explore structural alterations in the brains of people with bipolar disorder

A new study, led by USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), will explore structural alterations in the brains of people with bipolar disorder (BD), a chronic mental illness with one of the highest rates of attempted suicide - and for which no biological tools currently exist to guide diagnosis or treatment.

29 Jan 2025

Chemotherapy linked to persistent nerve pain in 4 in 10 cancer patients

Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published in the open access journal Regional Anesthesia & Pain Medicine.

29 Jan 2025