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Study: Overweight perception is independent predictor for suicidal ideation

Seeing oneself as overweight or obese may be an important, independent predictor of suicidal thoughts, especially in young girls, reports a new study in the Journal of Adolescent Health.

30 Aug 2013

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

A new weakness has been discovered in cancer cells that may make them more susceptible to chemotherapy and other treatments. In a research report appearing in the September 2013 issue of The FASEB Journal, scientists identify the HDAC5 protein as being essential for the maintenance of structures, called telomeres, within cancer cells that promote cancer cells longevity.

30 Aug 2013

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the initiation of a double blind, placebo controlled, Phase 2b dose ranging study of DEZ-001 (previously TA-8995), alone and in combination with statins, in order to study the effects on a wide range of lipids and other biomarkers of cardiovascular disease in patients with mild dyslipidemia.

30 Aug 2013

Potential drug target to treat depression and other mood disorders may lie in GABA neurons

A new drug target to treat depression and other mood disorders may lie in a group of GABA neurons (gamma-aminobutyric acid -the neurotransmitters which inhibit other cells) shown to contribute to symptoms like social withdrawal and increased anxiety, Penn Medicine researchers report in a new study in the Journal of Neuroscience.

30 Aug 2013

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

According to new research published in The FASEB Journal, a drop in blood zinc levels does not directly harm the blood vessel cells. Rather, zinc regulates the production of a small molecular compound, which then circulates in the blood and causes harmful blood vessel cell effects.

30 Aug 2013

Urinary protein may be early warning sign regarding patients' cognitive abilities

The presence of protein in the urine may be a marker of risk for future cognitive decline in patients with type 2 diabetes and normal kidney function, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

30 Aug 2013

Socioeconomic status more important barrier to living kidney donation than cultural factors

Socioeconomic status is a more important barrier to living kidney donation than cultural factors, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings may be useful for determining ways to increase living kidney donation in the United States.

30 Aug 2013

Study finds low adiponectin levels prior to pregnancy linked to high risk of gestational diabetes

Overweight women with low levels of the hormone adiponectin prior to pregnancy are nearly seven times more likely to develop gestational diabetes, according to a Kaiser Permanente study published today in the journal Diabetes Care. Adiponectin protects against insulin resistance, inflammation and heart disease.

30 Aug 2013

Researchers discover protein that may help predict breast cancer prognosis

Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring the most successful treatments for those at high risk. The research was published ahead of print in the journal Molecular and Cellular Biology.

30 Aug 2013

Engaging in physical activity not going to put at greater risk of knee osteoarthritis

Adults age 45 and older who engaged in moderate physical activity up to two and a half hours a week did not increase their risk of developing knee osteoarthritis over a 6-year follow-up period, a new study finds.

29 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Mallinckrodt to present MNK-795 clinical data at PAINWeek 2013

Mallinckrodt announced today that the first clinical data on MNK-795 will be presented at PAINWeek 2013, to be held September 4-7 in Las Vegas. MNK-795 is an extended-release oral formulation of oxycodone and acetaminophen that has been studied in clinical trials for the management of moderate to severe acute pain where the use of an opioid analgesic is appropriate.

29 Aug 2013

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

Researchers at Lund University have unexpectedly discovered that an old cancer drug can be used to prevent rejection of transplanted tissue. The researchers now have high hopes that their discovery could lead to new treatments for both transplant patients and patients with autoimmune diseases.

29 Aug 2013

AARDA study reveals mothers antibodies may cause autism in babies

A new, large-scale study of more than 2,700 mothers of children with autism shows that about one in 10 mothers have antibodies in their bloodstream that react with proteins in the brain of their babies.

29 Aug 2013

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Pharmacyclics, Inc. (Nasdaq: PCYC) today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing its New Drug Application (NDA) for the investigational oral Bruton's tyrosine kinase (BTK) inhibitor ibrutinib, for two B-cell malignancy indications: previously treated mantle cell lymphoma (MCL) and previously treated chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

29 Aug 2013

Mental and substance use disorders responsible for more death and illness worldwide

Mental and substance use disorders were the leading cause of non-fatal illness worldwide in 2010, according to a new analysis from the Global Burden of Disease Study, published in The Lancet.

29 Aug 2013

Many men find prostate cancer treatment as a big challenge

After fighting off prostate cancer and beginning the road to recovery, many men are finding the expense of cancer treatment is almost as big a challenge as the disease.

29 Aug 2013

European Commission approves EYLEA for treatment of visual impairment due to macular edema following CRVO

Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that EYLEA® (aflibercept) Injection has been approved by the European Commission for the treatment of visual impairment due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO).

29 Aug 2013

Study reveals relationship between migraine and low income status

Studies show that migraine is more common among people with lower incomes. This relationship is examined in a study published in the August 28, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology, looking at whether developing migraines limits people's educational and career achievements, leading to a lower income status, or whether problems related to low income such as stressful life events and poor access to health care increase the likelihood of developing migraines.

29 Aug 2013

Biostatistician uses statistical and computer modeling for policy development in prostate cancer research

Ruth Etzioni, Ph.D., a biostatistician, is a member of the Public Health Sciences Division at Fred Hutchinson Cancer Research Center.

29 Aug 2013

Medical Condition News

Study: Overweight perception is independent predictor for suicidal ideation

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Potential drug target to treat depression and other mood disorders may lie in GABA neurons

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

Urinary protein may be early warning sign regarding patients' cognitive abilities

Socioeconomic status more important barrier to living kidney donation than cultural factors

Study finds low adiponectin levels prior to pregnancy linked to high risk of gestational diabetes

Researchers discover protein that may help predict breast cancer prognosis

Engaging in physical activity not going to put at greater risk of knee osteoarthritis

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Mallinckrodt to present MNK-795 clinical data at PAINWeek 2013

Researchers discover old cancer drug can be used to prevent rejection of transplanted tissue

AARDA study reveals mothers antibodies may cause autism in babies

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Mental and substance use disorders responsible for more death and illness worldwide

Many men find prostate cancer treatment as a big challenge

European Commission approves EYLEA for treatment of visual impairment due to macular edema following CRVO

Study reveals relationship between migraine and low income status

Biostatistician uses statistical and computer modeling for policy development in prostate cancer research

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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