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Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

A pathway known for its role in regulating adult stem cells has been shown to be important for hair follicle proliferation, but contrary to previous studies, is not required within hair follicle stem cells for their survival, according to researchers with the Perelman School of Medicine at the University of Pennsylvania.

5 Dec 2013

Cardiac patients benefit from home-based high intensity training

Rapid rehabilitation is a must after a heart attack or other cardiovascular event. Different forms of exercise as a part of rehabilitation have been examined by researchers, including high-intensity interval training (85-95 % of maximum heart rate), which has proved to be both a good and efficient form of rehabilitation.

5 Dec 2013

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

A Cleveland Clinic-led study shows that a specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes by up to 32 percent.

5 Dec 2013

CEL-SCI gets approval to start enrollment for Multikine Phase III study for head and neck cancer

Further advancing one of the largest Phase III trials for head and neck cancer in the world, CEL-SCI Corporation announced today that it has received approval from the Agency for Medicaments and Medical Devices of the government of Bosnia and Herzegovina to begin enrollment of subjects into the Phase III Head and Neck Cancer clinical trial of its investigational cancer immunotherapy treatment Multikine (Leukocyte Interleukin, Injection).

5 Dec 2013

Presence Health uses automated IVR calls to increase colorectal cancer screening rates

Presence Health, the largest Catholic health system based in Illinois, significantly increased screening rates for colorectal cancer by utilizing automated, interactive voice response calls, according to research being presented on Dec. 10 at the Institute for Healthcare Improvement's 25th Annual National Forum on Quality Improvement in Health Care.

5 Dec 2013

AtheroNova completes active treatment portion of Phase 1 clinical trial with AHRO-001

AtheroNova Inc., a biotech company focused on the research and development of compounds to safely regress atherosclerotic plaque and improve lipid profiles in humans, today announces achievement of a major milestone with the completion of the active treatment portion of its Phase 1 clinical trial with its lead compound, AHRO-001. The Phase 1 study objective is to evaluate the safety, tolerability and pharmacokinetics of AHRO-001 in healthy volunteers. The clinical study is being conducted in Russia with AtheroNova's licensing partner, OOO CardioNova.

5 Dec 2013

Psychological well-being may play key role in maintenance of mental health

A study published in the current issue of Psychotherapy and Psychosomatics has examined psychological well-being in patients who have recovered from depression.

5 Dec 2013

Soligenix initiates SGX942 Phase 2 study for treatment of oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that it has initiated a Phase 2, randomized, double-blind, placebo-controlled study evaluating SGX942, a first-in-class innate defense regulator, as a treatment for oral mucositis in patients undergoing chemoradiation therapy for head and neck cancer.

5 Dec 2013

Mylan Pharmaceuticals introduces Cabergoline Tablets USP, 0.5 mg

Mylan Inc. today announced that its U.S.-based subsidiary Mylan Pharmaceuticals Inc. has launched Cabergoline Tablets USP, 0.5 mg. Cabergoline Tablets USP are indicated for the treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas. Mylan received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application for this product.

5 Dec 2013

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Biothera researchers have broadened their understanding of a biomarker that may enable doctors to predict which cancer patients will best respond to Imprime PGG®, the company's immunotherapy in Phase 3 drug development for colorectal cancer.

5 Dec 2013

Type 2 diabetes management: an interview with Professor Klaus Dugi, Corporate Senior Vice President Medicine, Boehringer Ingelheim

The rate of Type 2 Diabetes is rapidly increasing, particularly in Asian countries which make up more than 60 percent of the world’s diabetes population. So it’s really important physicians feel confident managing this chronic condition in their daily clinical practice.

5 Dec 2013

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy bone. However, excessive osteoclast activity leads to bone destruction in skeletal diseases such as osteoporosis, rheumatoid arthritis and cancer metastases in bone. A family of signaling enzymes known as phosphatidylinositol 3-kinases control diverse cell functions but, up until now, little was known about the function of specific PI3K isoforms in osteoclasts.

5 Dec 2013

Capsule endoscopy could identify presence of "occult" blood at very low levels

A tiny capsule that can carry out a chemical analysis of the contents of one's stomach could identify the presence of so-called "occult" blood at very low levels. The data is automatically broadcast to an external monitoring device for detection of early stage stomach cancer by one's physician. Details of the invention and initial trials are described in a forthcoming issue of the International Journal of Biomedical Engineering and Technology.

5 Dec 2013

Long-term ECG may help patients suffering from chronic cardiac insufficiency

Patients suffering from cardiac diseases may rapidly become emergencies. Then, seconds decide about life and death. However, many cardiac diseases are announced several months before. Symptoms are simply overlooked. A long-term ECG may help. A sensor belt developed at KIT for the first time allows to document cardiac activity of a patient over a long term all around the clock for up to six months. The sensor belt is now presented by the researchers at the Medica trade fair in Düsseldorf.

5 Dec 2013

St. Jude Medical evaluates effectiveness of PNfS and SCS for chronic low back and leg pain

St. Jude Medical, Inc., a global medical device company, has launched a clinical study to evaluate the combination of peripheral nerve field stimulation, and spinal cord stimulation, to determine whether the two therapies together offer more effective management of chronic low back and leg pain than SCS alone. The first patient in the SENSE Subcutaneous and Epidural Neuromodulation System Evaluation study was enrolled by Dr. Thomas Yearwood, an interventional pain physician at Comprehensive Pain & Rehabilitation in Pascagoula, Miss.

5 Dec 2013

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Researchers at the Department of Orthopaedics, of the Second Affiliated Hospital of Xi'an Jiaotong University Health Science Center, led by Dr. Kunzheng Wang and Dr. Pei Yang have developed a novel biomimetic tissue engineered bone graft based on rabbit adipose derived stem cells (rASCs), collagen I and a porous beta-tricalcium phosphate (β-TCP) scaffold.

5 Dec 2013

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Subthalamic nucleus deep brain stimulation can significantly improve the motor features of the Parkinson's disease in carefully selected patients. However, effects of subthalamic nucleus deep brain stimulation on the social adjustment, coping strategies and mental health-related quality of life of these patients remain unclear.

5 Dec 2013

Study: Social ties more important than biological development as predictors of teen sleep behaviors

Medical researchers point to developmental factors, specifically the decline of the sleep-inducing hormone melatonin, as an explanation for why children get less sleep as they become teenagers.

5 Dec 2013

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

A University of Colorado Cancer Center study published online ahead of print in the journal Nutrition and Cancer describes the laboratory synthesis of the most active component of grape seed extract, B2G2, and shows this synthesized compound induces the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed.

5 Dec 2013

Archimedes Model simulation suggests genetic screening for breast cancer risk can reduce deaths

Archimedes Inc., a healthcare modeling and analytics company, today announced results of a simulated clinical trial which found that the seven single-nucleotide polymorphisms (7SNP) genetic test for breast cancer was most cost effective when used to guide MRI screenings for patients found to have an intermediate lifetime risk of developing the disease.

5 Dec 2013

Medical Condition News

Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

Cardiac patients benefit from home-based high intensity training

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

CEL-SCI gets approval to start enrollment for Multikine Phase III study for head and neck cancer

Presence Health uses automated IVR calls to increase colorectal cancer screening rates

AtheroNova completes active treatment portion of Phase 1 clinical trial with AHRO-001

Psychological well-being may play key role in maintenance of mental health

Soligenix initiates SGX942 Phase 2 study for treatment of oral mucositis

Mylan Pharmaceuticals introduces Cabergoline Tablets USP, 0.5 mg

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Type 2 diabetes management: an interview with Professor Klaus Dugi, Corporate Senior Vice President Medicine, Boehringer Ingelheim

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

Capsule endoscopy could identify presence of "occult" blood at very low levels

Long-term ECG may help patients suffering from chronic cardiac insufficiency

St. Jude Medical evaluates effectiveness of PNfS and SCS for chronic low back and leg pain

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Study: Social ties more important than biological development as predictors of teen sleep behaviors

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

Archimedes Model simulation suggests genetic screening for breast cancer risk can reduce deaths

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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