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Montreal scientists develop novel approach for scanning entire genome

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient's genetic profile -also known as personalized medicine - we need to know how this genetic variant affects health.

1 Aug 2013

Research identifies important mechanism behind bladder cancer

Bladder cancer is a common condition - an estimated 10,000 people are diagnosed with the disease each year in the UK. It is the seventh most common cancer in the UK, affecting men more than women.

1 Aug 2013

CCTA offers alternative means of improving triage of chest pain patients: Study

A study of two sets of 894 matched Emergency Department patients presenting with chest pain revealed that the use of coronary computed tomographic angiography led to fewer hospital admissions and shorter ED stays. According to lead researcher Michael Poon, MD, of Stony Brook University School of Medicine, the findings provide evidence that CCTA offers an alternative means of improving the triage of chest pain patients.

1 Aug 2013

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

Afatinib has a novel mode of action and data has shown that it offers a clinical benefit to patients with a specific type of lung cancer, which we are further investigating in the extensive LUX-Lung clinical trial programme.

1 Aug 2013

Naked mole rat: A fitting model for finding novel ways to fight cancer

Mice and rats have long since been a standard animal model for cancer research, mainly due to their short lifespan of four years on average and high incidence of cancer. Naked mole rats however, are a mystery among mammals. This social tiny African subterranean rodent has a maximum lifespan exceeding 30 years and most surprisingly, is cancer-resistant.

1 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

Researcher receives grant to study how exposure to social stress impacts the brain and behavior

Dr. Kim Huhman, a researcher in the Center for Behavioral Neuroscience at Georgia State University, has received a federal five-year, $1.8 million grant for research that may lead to improved strategies for treating and preventing mental health problems associated with exposure to social stress.

1 Aug 2013

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Eight years ago, two former Stanford University postdoctoral fellows, one of them still in California and the other at the Harvard Stem Cell Institute in Cambridge, began exchanging theories about why patients with leukemia stop producing healthy blood cells. What was it, they asked, that caused bone marrow to stop producing normal blood-producing cells?

1 Aug 2013

FDA recalls Nova Max Blood Glucose Test Strips due to faulty readings

The U.S. Food and Drug Administration is working with Nova Diabetes Care to recall 21 lots of glucose test strips marketed under the brand names Nova Max Blood Glucose Test Strips and Nova Max Plus Glucose Meter Kits. Nova Diabetes Care announced a recall on July 26, 2013.

1 Aug 2013

New NIH projects to target Fragile X syndrome, nicotine addiction and AMD

The National Institutes of Health has launched three innovative projects that will focus on development of therapeutics for Fragile X syndrome, nicotine addiction, and age-related macular degeneration. These projects are funded through the NIH Blueprint Neurotherapeutics Network which provides access to a variety of drug development resources.

1 Aug 2013

Researchers find new way to help surgeons more accurately plan for epilepsy surgery

A brain imaging research team led by Simon Fraser University neuroscientist Dr. Ryan D'Arcy has found a new way to help surgeons more accurately plan for surgical treatment in epilepsy.

1 Aug 2013

MIT researchers develop photometric stereo endoscopy to detect precancerous lesions

MIT researchers have developed a new endoscopy technology that could make it easier for doctors to detect precancerous lesions in the colon. Early detection of such lesions has been shown to reduce death rates from colorectal cancer, which kills about 50,000 people per year in the United States.

1 Aug 2013

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Administering the drug rituximab once weekly for one month provides the same benefits as 18 months of daily immunosuppressive therapy in people with severe forms of vasculitis, or inflammation of the blood vessels, a study has found.

1 Aug 2013

Lupin gets tentative approval from FDA for Armodafinil Tablets, Doxycycline Capsules

elsPharma Major Lupin Limited announced that its U.S. subsidiary, Lupin Pharmaceuticals, Inc. has received tentative approval for its Armodafinil Tablets, 50 mg, 100 mg, 150 mg, 200 mg and 250 mg strengths as well as another tentative approval for its Doxycycline Capsules, 40 mg (30 mg Immediate-release and 10 mg Delayed-release) from the United States Food and Drugs Administration.

1 Aug 2013

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Scientists seeking to harness the healing power of a miniscule signaling molecule that plays a critical role in certain acute and chronic diseases have been awarded a Program Project Grant (PPG) of nearly $10 million by the National Heart, Lung and Blood Institute of the National Institutes of Health.

1 Aug 2013

Study: Anemia may increase risk of dementia

Anemia, or low levels of red blood cells, may increase the risk of dementia, according to a study published in the July 31, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

1 Aug 2013

Novel protein could lead to development of new drugs to treat variety of cancers

In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting.

1 Aug 2013

Genetics could help women at risk of developing gestational diabetes

New Northwestern Medicine- research on the genetics of diabetes could one day help women know their risk for developing gestational diabetes before they become pregnant -- and lead to preventive measures to protect the health of offspring.

1 Aug 2013

Fertility medications not linked with increased risk of CVD later in life

Women who gave birth following fertility treatment had no long-term increased risk of death or major cardiovascular events compared to women who gave birth without fertility therapy, according to new research by the Institute for Clinical Evaluative Sciences (ICES) and Women's College Hospital.

1 Aug 2013

Brain development delay throughout childhood and adolescence for people born with FASD

Medical researchers at the University of Alberta recently published findings showing that brain development is delayed throughout childhood and adolescence for people born with Fetal Alcohol Spectrum Disorder (FASD).

1 Aug 2013

Medical Condition News

Montreal scientists develop novel approach for scanning entire genome

Research identifies important mechanism behind bladder cancer

CCTA offers alternative means of improving triage of chest pain patients: Study

Phase III trial shows afatinib offers clinical benefit to patients with EGFR mutation positive NSCLC

Naked mole rat: A fitting model for finding novel ways to fight cancer

Transmembrane protein NG2 controls orientation of cell migration toward the wound

Researcher receives grant to study how exposure to social stress impacts the brain and behavior

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

FDA recalls Nova Max Blood Glucose Test Strips due to faulty readings

New NIH projects to target Fragile X syndrome, nicotine addiction and AMD

Researchers find new way to help surgeons more accurately plan for epilepsy surgery

MIT researchers develop photometric stereo endoscopy to detect precancerous lesions

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Lupin gets tentative approval from FDA for Armodafinil Tablets, Doxycycline Capsules

Miniscule signaling molecule plays critical role in certain acute and chronic diseases

Study: Anemia may increase risk of dementia

Novel protein could lead to development of new drugs to treat variety of cancers

Genetics could help women at risk of developing gestational diabetes

Fertility medications not linked with increased risk of CVD later in life

Brain development delay throughout childhood and adolescence for people born with FASD

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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