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Results from Amgen’s Neulasta plus bevacizumab Phase 3 trial on colorectal cancer

Amgen announced today results from Pegfilgrastim and Anti-VEGF Evaluation Study (PAVES), a Phase 3 trial which evaluated Neulasta (pegfilgrastim) in 845 patients receiving FOLFOX or FOLFIRI and bevacizumab for the first-line treatment of locally-advanced or metastatic colorectal cancer.

28 Jan 2013

Telomerase gene mutation immortalizes deadly skin cancer

About ten percent of all cases of malignant melanoma are familial cases. The genome of affected families tells scientists a lot about how the disease develops. Prof. Dr. Rajiv Kumar of the German Cancer Research Center together with Prof. Dr. Dirk Schadendorf from Essen University Hospital studied a family where 14 family members were affected by malignant melanoma.

28 Jan 2013

Research roundup: Does higher Rx drug spending lower Medicare costs?; Price transparency doesn't affect radiological decisions

Researchers aimed to find a relationship between geographic variation in Medicare Part D spending and medication-taking behavior among patients with diabetes or heart failure.

28 Jan 2013

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Seattle Genetics, Inc. today presented interim results from a phase I clinical trial evaluating ASG-5ME for the treatment of metastatic pancreatic ductal adenocarcinoma (PDA) at the American Society of Clinical Oncology (ASCO) 2013 Gastrointestinal Cancers Symposium being held January 24-26, 2013 in San Francisco, CA.

28 Jan 2013

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

The U.S. Food and Drug Administration today approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochloride) tablets, and Oseni (alogliptin and pioglitazone) tablets.

28 Jan 2013

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

27 Jan 2013

New research on flavonoids and nutritional health in older adults from JONGG

Routledge Journals is pleased to announce a Special Issue from the Journal of Nutrition in Gerontology and Geriatrics focusing on the impact of flavonoids on the nutritional health of older adults.

27 Jan 2013

Short-term use of folic acid supplements unlikely to increase cancer risk

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25 Jan 2013

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Infectious diseases in Ghana tend to capture the most attention, but a quiet crisis may soon take over as the country's most threatening epidemic: cancer.

25 Jan 2013

Ohio State's Wexner Medical Center performs DBS surgery on Alzheimer's patient

During a five-hour surgery last October at The Ohio State University Wexner Medical Center, Kathy Sanford became the first Alzheimer's patient in the United States to have a pacemaker implanted in her brain.

25 Jan 2013

Researchers study innovative stem cell drug for treating localized cartilage damage

Rush University Medical Center is conducting the nation's first clinical study of an innovative stem cell drug, Cartistem, to repair knee cartilage damaged by aging, trauma or degenerative diseases such as osteoarthritis.

25 Jan 2013

Findings could help develop targeted exercise for obese women with Type 2 diabetes

More than one-third of Americans are obese, and these individuals often experience accompanying health issues, such as Type 2 diabetes and cardiovascular problems. In response to the so-called "obesity epidemic," many medical professionals have suggested ways to improve the health outcomes of obese individuals through diet and exercise.

25 Jan 2013

African-American women who reported childhood abuse had greater risk of uterine fibroids

According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared with women who had no such abuse history.

25 Jan 2013

Researchers identify cancer-associated mutations

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously found.

25 Jan 2013

Prenatal inflammation associated with increased risk of autism in children

Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health. Researchers found this in children of mothers with elevated C-reactive protein (CRP), a well-established marker of systemic inflammation.

25 Jan 2013

Genome sequencing data gives important clues on cancer

Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease.

25 Jan 2013

Reuters reports on obesity talks at World Economic Forum

Reuters reports on discussions taking place at the World Economic Forum (WEF), taking place in Davos, Switzerland, this week, writing, "Obesity, a major factor in diabetes and heart disease, imposes costs on both public and private sectors and is a drag on economic growth, but business leaders meeting in Davos can't agree on what they can or should do to address it."

25 Jan 2013

Mount Sinai sets up new center for treating tic and obsessive-compulsive disorders

Mount Sinai has officially opened a new center to treat and research tic and obsessive-compulsive disorders (OCD) in individuals of all ages. The opening coincides with a significant revision in the psychiatry field's manual of mental disorders, which will now recognize OCD with its own category, rather than classifying it as an anxiety disorder.

25 Jan 2013

Subsidised antimalarial drugs: an interview with Kara Hanson

Artemisinin-based combination therapies (ACTs) are the currently recommended drugs for treating malaria. However, they are expensive, which limits their affordability. This means that people with malaria are likely to buy cheaper, less effective antimalarials such as chloroquine and sulphadoxine-pyrimethamine; or to simply buy painkillers and antipyretics.

25 Jan 2013

New study may help treat patients with multiple myeloma

A study led by Robert G. Hawley, Ph.D., professor and chair of the department of anatomy and regenerative biology at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), may help predict which patients with multiple myeloma will respond better to certain treatments.

25 Jan 2013

Medical Condition News

Results from Amgen’s Neulasta plus bevacizumab Phase 3 trial on colorectal cancer

Telomerase gene mutation immortalizes deadly skin cancer

Research roundup: Does higher Rx drug spending lower Medicare costs?; Price transparency doesn't affect radiological decisions

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

New research on flavonoids and nutritional health in older adults from JONGG

Short-term use of folic acid supplements unlikely to increase cancer risk

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Ohio State's Wexner Medical Center performs DBS surgery on Alzheimer's patient

Researchers study innovative stem cell drug for treating localized cartilage damage

Findings could help develop targeted exercise for obese women with Type 2 diabetes

African-American women who reported childhood abuse had greater risk of uterine fibroids

Researchers identify cancer-associated mutations

Prenatal inflammation associated with increased risk of autism in children

Genome sequencing data gives important clues on cancer

Reuters reports on obesity talks at World Economic Forum

Mount Sinai sets up new center for treating tic and obsessive-compulsive disorders

Subsidised antimalarial drugs: an interview with Kara Hanson

New study may help treat patients with multiple myeloma

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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