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FDA issues Complete Response Letter to Allergan's NDA for LEVADEX

Allergan, Inc. today announced that the U.S. Food and Drug Administration has issued a Complete Response Letter to its New Drug Application for LEVADEX (dihydroergotamine) inhalation aerosol for the acute treatment of migraine in adults.

17 Apr 2013

Research findings in mice may pave way towards understanding autism in human patients

For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals' chromosomes.

17 Apr 2013

Melanoma patients with lower educational background more likely to die of the disease

There are socioeconomic differences in Sweden in survival amongst people with malignant skin melanoma, according to a study published in the European Journal of Cancer.

17 Apr 2013

Researchers report progress on non-invasive method to assess kidney function

Researchers may have found a way to block kidney-destroying inflammation and help damaged kidney cells recover.

17 Apr 2013

Cardiovascular risk factors may be overlooked during survivorship care, research finds

Many people survive their cancers, but end up dying of cardiovascular disease. New research from Wake Forest Baptist Medical Center finds that CVD risk factors may be overlooked during survivorship care.

17 Apr 2013

UCLA researchers classify kidney cancer into several unique subtypes

Researchers with the Institute of Urologic Oncology and the Department of Urology at UCLA have classified kidney cancer into several unique subtypes, a finding that will help physicians tailor treatment to individual patients and that moves cancer care one step closer to personalized medicine.

17 Apr 2013

Study finds no evidence that digoxin increases mortality in patients with atrial fibrillation

A study published today in the European Heart Journal found no evidence that digoxin increases mortality in patients with atrial fibrillation, the opposite of results just published by another group in the same journal analyzing the same data.

17 Apr 2013

COPD phase III study by Almirall and Forest Laboratories announces positive results

Almirall, S.A. (ALM:MC) and Forest Laboratories, Inc. (NYSE:FRX) today announced positive topline results from a six month pivotal phase III clinical trial evaluating the efficacy and safety of fixed dose combinations of aclidinium bromide (LAMA) and formoterol fumarate (LABA) delivered by Almirall’s inhaler Genuair® (Pressair™ in the USA).

16 Apr 2013

Average annual incidence of sepsis varies depending on method used

Though the toll of sepsis is known to be enormous - it is estimated to cost the U.S. health care system $24.3 billion each year, and is the nation's third-leading killer, behind heart disease and cancer - the true magnitude of incidence of and death from the illness remains unknown.

16 Apr 2013

Depressed teenagers are more likely to have mental illness during twenties

Depressed teenagers are more likely to have serious problems during their twenties, including ongoing mental illness and excessive drinking, finds a recent study in the Journal of Adolescent Health.

16 Apr 2013

Research suggests fainting may be genetic while certain triggers may not be inherited

New research suggests that fainting may be genetic and, in some families, only one gene may be responsible. However, a predisposition to certain triggers, such as emotional distress or the sight of blood, may not be inherited.

16 Apr 2013

Study: Women with RA exposed to anti-tumor necrosis drugs may have increased abortion rates

A new study published in the American College of Rheumatology (ACR) journal, Arthritis Care & Research, reveals that women with rheumatoid arthritis (RA) who were on methotrexate (MTX), a drug commonly used to reduce inflammation caused by RA, had lower rates of induced abortions compared to women with RA who were not exposed to the medication.

16 Apr 2013

Study finds genetic variation is associated with pulmonary fibrosis risk

A newly published study of patients with pulmonary fibrosis has discovered multiple genetic variations that should help with future efforts to treat the disease.

16 Apr 2013

Adherence to "Western-style" diet may increase risk of cardiovascular diseases and diabetes

Data from a new study of British adults suggest that adherence to a "Western-style" diet (fried and sweet food, processed and red meat, refined grains, and high-fat dairy products) reduces a person's likelihood of achieving older ages in good health and with higher functionality. Study results appear in the May issue of The American Journal of Medicine.

16 Apr 2013

MRA awards $9M grant to scientists for exploring new treatments and cures for melanoma

The Melanoma Research Alliance (MRA), the largest private funder of melanoma research, today announced grant awards exceeding $9.6 million to 49 scientists at leading academic institutions around the world for investigating new treatments and cures for melanoma.

16 Apr 2013

Montreal scientists identify potential target to reduce progression of metastases in breast cancer patients

A team of researchers at the IRCM, led by Dr. Jean Franois Ct, made an important discovery in breast cancer, which will published online this week by the scientific journal Proceedings of the National Academy of Sciences (PNAS).

16 Apr 2013

Propranolol drug can improve language abilities, social functioning of people with ASD

People with an Autism Spectrum Disorder (ASD) often have trouble communicating and interacting with others because they process language, facial expressions and social cues differently.

16 Apr 2013

High levels of blood cholesterol increase risk of AD and heart disease

Researchers at the Linda Crnic Institute for Down Syndrome and the University of Colorado School of Medicine have found that a single mechanism may underlie the damaging effect of cholesterol on the brain and on blood vessels.

16 Apr 2013

Research: Gene expression signature may increase risk of tumor recurrence or spread prostate cancer

A team led by Massachusetts General Hospital researchers has identified a genetic signature that appears to reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer.

16 Apr 2013

Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

Rhythm announced today the initiation of an additional Phase 2 clinical trial for RM-131, the company's novel ghrelin agonist, for the treatment of chronic constipation. Ghrelin is a peptide hormone produced in the stomach that stimulates gastrointestinal motility.

16 Apr 2013

Medical Condition News

FDA issues Complete Response Letter to Allergan's NDA for LEVADEX

Research findings in mice may pave way towards understanding autism in human patients

Melanoma patients with lower educational background more likely to die of the disease

Researchers report progress on non-invasive method to assess kidney function

Cardiovascular risk factors may be overlooked during survivorship care, research finds

UCLA researchers classify kidney cancer into several unique subtypes

Study finds no evidence that digoxin increases mortality in patients with atrial fibrillation

COPD phase III study by Almirall and Forest Laboratories announces positive results

Average annual incidence of sepsis varies depending on method used

Depressed teenagers are more likely to have mental illness during twenties

Research suggests fainting may be genetic while certain triggers may not be inherited

Study: Women with RA exposed to anti-tumor necrosis drugs may have increased abortion rates

Study finds genetic variation is associated with pulmonary fibrosis risk

Adherence to "Western-style" diet may increase risk of cardiovascular diseases and diabetes

MRA awards $9M grant to scientists for exploring new treatments and cures for melanoma

Montreal scientists identify potential target to reduce progression of metastases in breast cancer patients

Propranolol drug can improve language abilities, social functioning of people with ASD

High levels of blood cholesterol increase risk of AD and heart disease

Research: Gene expression signature may increase risk of tumor recurrence or spread prostate cancer

Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

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