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Foresee, ScinoPharm to form joint venture for new oncological Leuprolide injectable drug

ScinoPharm and Foresee Pharmaceuticals, Inc. jointly announced today that an investment agreement to form a joint venture has been signed. This venture looks to develop a series of peptide injectable drugs with the first being a new oncological Leuprolide injectable drug product, where Leuprolide will be formulated in a proprietary controlled-release drug delivery system originally developed by Foresee and transferred to the joint venture.

30 Jan 2013

UCLA's Laboratory of Neuro Imaging to use expertise to piece together brain's puzzle

UCLA's Laboratory of Neuro Imaging (LONI) has entered into a partnership with academic centers from Europe and around the world in a massive, unprecedented effort to understand the human brain.

30 Jan 2013

Hydrogen sulfide may play a wide-ranging role in staving off aging

Hydrogen sulfide (H2S) may play a wide-ranging role in staving off aging, according to a paper published online ahead of print in the journal Molecular and Cellular Biology.

30 Jan 2013

Massage therapy can lower blood pressure, help prevent colds and enhance skin tone

Massage therapy can lower blood pressure, help prevent colds, enhance skin tone and more, according to an expert at the University of Alabama at Birmingham (UAB).

30 Jan 2013

Breathing indoor air carries significant cancer risks for Chinese women

The hazards of breathing outdoor air in some Chinese cities have been well-documented. Now a University at Buffalo study confirms that breathing indoor air also carries significant cancer risks, especially for Chinese women.

30 Jan 2013

Noninvasive, drugless therapy may help mitigate symptoms associated with neurological conditions

With the infusion of an additional $1 million of financial support from The Susanne Marcus Collins Foundation, Inc., Atlanta, GA, Wake Forest Baptist Medical Center researchers are expanding their studies using a noninvasive, drugless therapy that may help to mitigate symptoms associated with a list of neurological conditions.

30 Jan 2013

Brain areas work together at the same time to recall memories

Working with patients with electrodes implanted in their brains, researchers at the University of California, Davis, and The University of Texas Health Science Center at Houston (UTHealth) have shown for the first time that areas of the brain work together at the same time to recall memories. The unique approach promises new insights into how we remember details of time and place.

30 Jan 2013

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins - known as Src - leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature Communications that beta blocker drugs mitigate this effect and reduce cancer deaths by an average of 17 percent.

30 Jan 2013

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

AvidBiologics Inc., a life sciences company developing antibody-drug conjugates (ADCs), announces the conclusion of an agreement with the National Research Council Canada (NRC) to develop three novel ADCs for the treatment of cancer.

30 Jan 2013

HIV-positive patients have higher incidence of non-melanoma skin cancers

HIV-positive patients have a higher incidence of non-melanoma skin cancers, according to a Kaiser Permanente study that appears in the current online issue of the Journal of the National Cancer Institute. Specifically, basal cell and squamous cell carcinomas occur more than twice as often among HIV-positive individuals compared to those who are HIV-negative.

30 Jan 2013

FBH1 gene helps turn up the effect of chemotherapy

Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research and Innovation Centre (BRIC) and Center for Healthy Aging, University of Copenhagen, now show that the gene FBH1 helps turn up the effect of chemotherapy.

30 Jan 2013

DFG again approves funding for Mainz University to promote cardiovascular research

The German Research Foundation (DFG) has again approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote cardiovascular research - for the second time within only a few weeks.

30 Jan 2013

FDA approves Genzyme’s KYNAMRO to treat homozygous familial hypercholesterolemia

Genzyme, a Sanofi company, and Isis Pharmaceuticals Inc., today announced that the U.S. Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for KYNAMROTM (mipomersen sodium) injection.

30 Jan 2013

SOD1 enzyme protects cells by regulating cell energy and metabolism

Just like a comic book super hero, you could say that the enzyme superoxide dismutase (SOD1) has a secret identity. Since its discovery in 1969, scientists believed SOD1's only role was to protect living cells against damage from free radicals. Now, researchers at the Johns Hopkins Bloomberg School of Public Health have discovered that SOD1 protects cells by regulating cell energy and metabolism. The results of their research were published January 17, 2013, in the journal Cell.

30 Jan 2013

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its investigational protein therapeutic, ACE-536, to treat anemia in patients with myelodysplastic syndromes (MDS).

30 Jan 2013

Phenformin decreases size of lung tumors and increases survival in mice

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer.

30 Jan 2013

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

OncoPep, Inc. today announced that the Company has initiated a Phase 1/2a clinical trial evaluating PVX-410, a multi-peptide therapeutic cancer vaccine, in patients with smoldering multiple myeloma, an asymptomatic precursor of multiple myeloma, which is an incurable cancer of the plasma cells.

30 Jan 2013

U-M to host 11th-annual Depression on College Campuses Conference on Feb. 26-27

Rather than seeking out healthy treatment options, many college students experiencing symptoms of depression or anxiety too often resort to unhealthy coping practices like drug use, drinking, or self-injury.

30 Jan 2013

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

ImmunoCellular Therapeutics, Ltd. announced that the US Food and Drug Administration (FDA) has allowed the investigational new drug (IND) application for ICT-140, paving the way for conducting a clinical trial.

30 Jan 2013