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Sequana Medical's ALFApump System safe and effective in managing ascites

Sequana Medical announced that initial results from the PIONEER Clinical Study of its ALFApump System were presented today at the 47th annual European Association for Study of the Liver Meeting in Barcelona.

21 Apr 2012

Large doses of vitamin C may moderately reduce blood pressure

Taking large doses of vitamin C may moderately reduce blood pressure, according to an analysis of years of research by Johns Hopkins scientists. But the researchers stopped short of suggesting people load up on supplements.

21 Apr 2012

Researchers discover novel genetic mechanism of idiopathic CD4 lymphopenia

Researchers at National Jewish Health have discovered a novel genetic mechanism of immune deficiency. Magdalena M. Gorska, MD, PhD, and Rafeul Alam, MD, PhD, identified a mutation in Unc119 that causes immunodeficiency known as idiopathic CD4 lymphopenia.

21 Apr 2012

Positive results from Alnylam’s ALN-PCS Phase I trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive results from its Phase I clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

21 Apr 2012

Depression may increase risk of peripheral artery disease

Depression may be associated with an increased risk of arterial narrowing in the legs and pelvis, a condition known as peripheral artery disease (PAD), according to research presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2012 Scientific Sessions in Chicago.

21 Apr 2012

ACT announces dosing of third patient in dry AMD Phase I/II trial

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today the dosing of the third patient in its Phase I/II trial for dry age-related macular degeneration (dry AMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells.

21 Apr 2012

Researchers revisit Charcot's vibration therapy for Parkinson's disease

In the 19th century, Jean-Martin Charcot, the celebrated neurologist, developed a "vibration chair," to relieve symptoms of Parkinson's disease. Charcot reported improvements in his patients, but he died shortly thereafter and a more complete evaluation of the therapy was never conducted.

20 Apr 2012

Nanoscale films promote bone growth

Every year, more than a million Americans receive an artificial hip or knee prosthesis. Such implants are designed to last many years, but in about 17 percent of patients who receive a total joint replacement, the implant eventually loosens and has to be replaced early, which can cause dangerous complications for elderly patients.

20 Apr 2012

National award celebrates landmark discovery in gut flora and cardiovascular disease

Stanley Hazen, M.D., Ph.D., was recently honored with an inaugural Top 10 Clinical Research Achievement Award from an organization comprised of the nation's most acclaimed academic medical centers and other groups, in recognition of Dr. Hazen's Nature article, "Gut flora dependent metabolism of dietary phosphatidylcholine contributes to cardiovascular disease."

20 Apr 2012

Possibility to render cancer tumours harmless without affecting other cells

New research findings show how it may be possible to render cancer tumours harmless without affecting the other cells and tissues in the body. The findings apply to cancers including breast, lung and bowel cancer. The study was carried out at Lund University in Sweden.

20 Apr 2012

Study determines importance of bacterial infections in cirrhosis

A South African study presented today determines the importance of bacterial infections, which commonly occur in cirrhosis and can alter the natural history of the condition, possibly leading to loss of liver function and decompensation. It is now recognised that many infections in cirrhotic patients result from bacterial translocation (BT) from the intestine.

20 Apr 2012

First study to look at link between gender and mother's cardiac disease

Women with heart disease are more likely to give birth to female rather than male babies according to a new study presented today at the World Congress of Cardiology. The study found that three-quarters of the 216 children born to 200 pregnant women with diagnosed heart disease were female.

20 Apr 2012

New evidence helps explain additional health benefits of aspirin

New evidence is helping explain additional health benefits of aspirin. Researchers in Canada, Scotland and Australia have discovered that salicylate, the active ingredient in aspirin, directly increases the activity of the protein AMPK (AMP-activated protein kinase), a key player in regulating cell growth and metabolism. AMPK which is considered a cellular fuel-gauge is switched on by exercise and the commonly used anti-diabetic medication metformin.

20 Apr 2012

Kessler Foundation scientist to develop predictive model of unemployment in MS

Lauren Strober, PhD, has been awarded a five-year federal grant for $554,000 to study factors relating to unemployment in people with multiple sclerosis (MS). Dr. Strober is a research scientist at Kessler Foundation, a major center for cognitive research and training in multiple sclerosis and a leader in the field of disability employment.

20 Apr 2012

RHD patients seek treatment in the very late stages of disease

Patients with rheumatic heart disease (RHD) are being admitted to hospital too late to prevent the need for heart surgery, according to a new study carried out by doctors in Yemen and presented today at the World Congress of Cardiology.

20 Apr 2012

Chip-scale NIST sensor successfully measures human brain activity

A miniature atom-based magnetic sensor developed by the National Institute of Standards and Technology (NIST) has passed an important research milestone by successfully measuring human brain activity. Experiments reported this week verify the sensor's potential for biomedical applications such as studying mental processes and advancing the understanding of neurological diseases.

20 Apr 2012

Many Americans struggle to regain health insurance after losing or changing jobs

One of four (26%) working-age U.S. adults experienced a gap in health insurance coverage during 2011, often because they lost or changed jobs, according to a new Commonwealth Fund report that also shows how difficult it is for people to regain health insurance on their own after losing employer-sponsored coverage.

20 Apr 2012

Longer looks: Rushed medicine; Exercising your way to a smarter brain

Something in the world of medicine is seriously amiss. Unhappy patients gripe about their doctors' brusque manner and give them bad marks on surveys and consumer websites like HealthGrades and Angie's List. They tell tales of being rushed out of the office by harried doctors who miss crucial diagnoses, never look up from their computers during an exam, make errors in prescriptions, and just plain don't listen to their patients. ... And things don't seem much better from the other side of the stethoscope.

20 Apr 2012

Omega-3 fatty acids inhibit detrimental effects of smoking on arterial function

Omega-3 fatty acids may help to reduce the physical harm caused by smoking, according to a new study presented today at the World Congress of Cardiology.

20 Apr 2012

Chinese scientists make significant breakthrough in animal cloning

Chinese scientists from BGI, the world's largest genomics organization, together with the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS), and Shihezi University, Xinjiang province, made a significant breakthrough in animal cloning.

20 Apr 2012