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Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments.

2 Feb 2013

Quantum dots can rapidly deliver calcitriol to targeted tumor sites for treatment of IBC

The shortened daylight of a Maine winter may make for long, dark nights - but it has shone a light on a novel experimental approach to fighting inflammatory breast cancer (IBC), an especially deadly form of breast cancer.

2 Feb 2013

CBT and graded exercise therapy increase likelihood of recovery from chronic fatigue syndrome

Research led by Queen Mary, University of London, has shown that recovery from chronic fatigue syndrome (CFS) is possible for some patients, and has identified two treatments most likely to lead to recovery.

2 Feb 2013

Study: OEND effectively addresses epidemic of fatal opioid overdose

In a study of communities in Massachusetts with high numbers of opioid overdose deaths, the implementation of overdose education and naloxone distribution (OEND) was associated with a significant reduction in opioid overdose death rates.

2 Feb 2013

Researchers determine differences in stiffness between healthy and cancerous tissue

The texture of breast cancer tissue differs from that of healthy tissue. Using a cutting-edge tissue diagnostic device, a group of researchers in Basel, Switzerland, has determined one key difference: cancerous tissue is a mix of stiff and soft zones, whereas healthy tissue has uniform stiffness.

2 Feb 2013

National Eye Institute’s booklet and videos help people adapt to life with low vision

A 20-page large-print booklet and a series of videos to help people adapt to life with low vision are available from the National Eye Institute (NEI), a part of the National Institutes of Health. The materials were released during Low Vision Awareness Month, February 2013.

2 Feb 2013

Neural stem cell transplantation shows promise against gastrointestinal motility disorders

Proper function of the digestive system requires coordinated contraction of the muscle in the wall of the intestinal tract, regulated by the enteric nervous system.

2 Feb 2013

DHEA-S may prevent neurocognitive impairment that affects AIDS patients

A team of scientists from Canada, Thailand and Morocco have found that DHEA-S may prevent neurocognitive impairment that affects a significant percentage of AIDS patients. In a report appearing in the February 2013 issue of The FASEB Journal, they describe how a network of steroid molecules found in the brain, termed "neurosteroids," is disrupted during HIV infection leading to brain damage.

2 Feb 2013

University of Kentucky professor to continue research into ruthenium-based cancer drugs

University of Kentucky assistant professor of chemistry Edith "Phoebe" Glazer has received an American Cancer Society Research Scholar Grant for $715,000 over four years to continue her research into ruthenium-based cancer drugs. These compounds are less toxic to healthy cells than a similar and widely used inorganic drug.

1 Feb 2013

Dairy intake may increase risk of bone mineral density in the hip

A study by researchers at the Institute for Aging Research (IFAR) at Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS), has found that dairy intake -specifically milk and yogurt -is associated with higher bone mineral density (BMD) in the hip, but not the spine.

1 Feb 2013

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

The U.S. Food and Drug Administration today approved Ravicti (glycerol phenylbutyrate) for the chronic management of some urea cycle disorders (UCDs) in patients ages 2 years and older.

1 Feb 2013

Scientists uncover key mechanism that links obesity and diabetes with cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also increase our chance to get cancer: The dose makes the poison as Paracelsus said.

1 Feb 2013

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Hundreds of healthcare professionals at the Cedars-Sinai Heart Institute will wear red on Friday, Feb. 1, to mark National Wear Red Day. A few hours later, the new Cedars-Sinai Advanced Health Sciences Pavilion will be lit with a projection of the red dress symbol that represents a public education program to boost women's awareness of heart disease.

1 Feb 2013

Scientists discover new evidence for role of epigenetic changes on premature aging diseases

Scientists at the Bellvitge Biomedical Research Institute in Barcelona, Spain have found new evidence for the role of epigenetic changes (those heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence) on premature aging diseases.

1 Feb 2013

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Improvements in the diagnosis and treatment of cancers in recent years have led to a marked increase in patients' physical survival rates. While doctors can treat the physical disease, what is not well understood is how best to address the psychological needs of patients with cancer.

1 Feb 2013

Two-step personalized immunotherapy safe for patients with ovarian cancer

Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine show that a two-step personalized immunotherapy treatment - a dendritic cell vaccine using patients' own tumor followed by adoptive T cell therapy - triggers anti-tumor immune responses in these type of patients.

1 Feb 2013

Scientists identify specific p53 pocket that can be targeted by cancer-fighting drugs

UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year.

1 Feb 2013

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Seattle Genetics, Inc. today announced that Health Canada has issued a Notice of Compliance with conditions (NOC/c), authorizing marketing of ADCETRIS for two lymphoma indications.

1 Feb 2013

Study investigates R1441G mutation of Parkinson's disease

A team from the UPV/EHU-University of the Basque Country came across a mutation of the LRRK2 gene in 2004, which is particularly prevalent among the population of Gipuzkoa. It is the R1441G mutation and is known as the Basque mutation.

1 Feb 2013

New CT system reduces radiation exposure in patients undergoing CCTA

Researchers using a newly approved advanced computed tomography (CT) system were able to significantly reduce radiation exposure in patients undergoing coronary CT angiography (CCTA), according to a new study published online in the journal Radiology.

1 Feb 2013

Medical Condition News

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Quantum dots can rapidly deliver calcitriol to targeted tumor sites for treatment of IBC

CBT and graded exercise therapy increase likelihood of recovery from chronic fatigue syndrome

Study: OEND effectively addresses epidemic of fatal opioid overdose

Researchers determine differences in stiffness between healthy and cancerous tissue

National Eye Institute’s booklet and videos help people adapt to life with low vision

Neural stem cell transplantation shows promise against gastrointestinal motility disorders

DHEA-S may prevent neurocognitive impairment that affects AIDS patients

University of Kentucky professor to continue research into ruthenium-based cancer drugs

Dairy intake may increase risk of bone mineral density in the hip

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

Scientists uncover key mechanism that links obesity and diabetes with cancer

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Scientists discover new evidence for role of epigenetic changes on premature aging diseases

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Two-step personalized immunotherapy safe for patients with ovarian cancer

Scientists identify specific p53 pocket that can be targeted by cancer-fighting drugs

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Study investigates R1441G mutation of Parkinson's disease

New CT system reduces radiation exposure in patients undergoing CCTA

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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