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Breast cancer cells that metastasize to the lung express higher level of PRDX2

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that breast cancer cells that metastasize to the lung express a higher level of the protein peroxiredoxin 2 (PRDX2). The study suggests that the modulation of the levels of this protein could be a new therapeutic strategy to prevent lung metastases.

11 Apr 2012

Amyloid precursor protein appears to regulate its own production

A research team led by the University of South Florida Department of Psychiatry & Behavioral Neurosciences has found that a fragment of the amyloid precursor protein (APP) -- known as sAPP-α and associated with Alzheimer's disease -- appears to regulate its own production.

11 Apr 2012

CLYD gene serves as crucial negative regulator in pulmonary fibrosis

An international team of researchers led by Georgia State University scientists have found a key component in the pathological process of pulmonary fibrosis, a fatal disease for which there is currently no cure.

11 Apr 2012

Majority of Michigan oncology practices follow treatment guidelines for common cancers

A majority of Michigan oncology practices participating in a statewide consortium followed treatment guidelines for common cancers, but had gaps in managing symptoms and end-of-life care, according to a new study.

11 Apr 2012

New 4th Edition of Practical Neurology for clinicians, residents and fellows

The new 4th Edition of Practical Neurology, the respected "real-life" guide to diagnosing and managing neurologic disorders, has been completely rewritten to known neurologist and chair of the Department of Neurology of Loyola University Chicago Stritch School of Medicine.

11 Apr 2012

Act of coming out associated with better health for LGB adults

A comprehensive new study led by Boston University School of Public Health (BUSPH) researcher Emily Rothman shows that two-thirds of lesbian, gay and bisexual adults in a representative Massachusetts sample reported receiving positive support from their parents after coming out to them. Their incidence of mental health and substance abuse problems was significantly lower than those who did not receive support, the authors reported.

11 Apr 2012

Mothers tend to be more critical of children with obsessive-compulsive disorder

A new study from Case Western Reserve University finds mothers tend to be more critical of children with obsessive-compulsive disorder than they are of other children in the family. And, that parental criticism is linked to poorer outcomes for the child after treatment.

11 Apr 2012

Lauren Sciences, BGN Technologies sign licensing agreement for V-Smart- drug delivery technology

BGN Technologies, the technology transfer company for Ben-Gurion University of the Negev (BGU), has signed a licensing agreement for its V-Smart- drug delivery technology with Lauren Sciences LLC, a privately held biotechnology company in New York.

11 Apr 2012

Study reveals difficulties in self-management of diabetes

A new study from researchers at Queen Mary, University of London reveals the many difficulties faced by people with diabetes in self-managing their disease.

11 Apr 2012

Siemens announces integrated imaging solution for detection of amyloid plaques

Siemens Healthcare is the first company worldwide to announce a complete integrated diagnostic imaging solution proposed for the detection of amyloid plaques — one of the necessary pathological features of Alzheimer's disease— in the living brain.

From Siemens Healthineers 11 Apr 2012

Botanical formula controls aggressive human prostate tumors in mice

A non-toxic, botanical formula controls aggressive human prostate tumors in mice, according to a peer-reviewed study in the The International Journal of Oncology. Researchers at Indiana University, Methodist Research Institute, showed the prostate formula significantly suppresses tumor growth in aggressive, hormone-refractory (androgen-independent) human prostate cancer cells.

11 Apr 2012

New report calls on nations to recognise dementia as a public health crisis

A report released today by the World Health Organization (WHO) and Alzheimer's Disease International (ADI) calls for governments and policymakers to make dementia a global public health priority.

11 Apr 2012

New method for direct identification of antigens

The immune system is a vital part of our defenses against pathogens, but it can also attack host tissues, resulting in autoimmune disease. The antigens that induce destructive immune reactions can now be identified directly - without any prior knowledge of their possible structure.

11 Apr 2012

EKG can detect heart attack in healthy senior citizens

Can a simple diagnostic test used to measure a heart's electrical activity help predict heart attacks? And can that knowledge help doctors reroute their patients away from coronary heart disease? These are the questions researchers at UCSF asked in a comprehensive eight-year study focused on senior citizens in the United States. Researchers found a higher risk of heart attack when abnormalities showed up on electrocardiogram (EKG) results of healthy elderly people.

11 Apr 2012

Women less likely to get at least 30 minutes of exercise per day

A national study shows that women are less likely than men to get at least 30 minutes of exercise per day, resulting in greater odds of developing metabolic syndrome - a risky and increasingly prevalent condition related to obesity.

11 Apr 2012

First large study to examine age, gender and sibling history on stroke risk

If your brother or sister had a stroke, you may be at least 60 percent more likely to have one too, according to research reported in the American Heart Association journal Circulation: Cardiovascular Genetics.

11 Apr 2012

QRxPharma completes MoxDuo CR Phase 1 studies on chronic pain

QRxPharma announced today successful completion of two Phase 1 studies in healthy volunteers for MoxDuo CR, a controlled-release Dual-Opioid utilising a 3:2 ratio of morphine and oxycodone.

11 Apr 2012

FDA approves Medtronic’s expanded indication for implantable CRT-D devices

Medtronic, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved an expanded indication for its cardiac resynchronization therapy with implantable cardioverter defibrillator (CRT-D) devices.

From Medtronic 11 Apr 2012

New Contemplative Sciences Center at University of Virginia

Can meditation, yoga or mindfulness training help nurses and teachers be more effective and resilient in stressful situations? Can such contemplative practices be part of a more effective treatment regimen for major depression, or for alcoholics in recovery?

11 Apr 2012

Rate of childhood obesity triples in 30 years

Nearly 18 percent of U.S. school-aged children and adolescents are obese, as the rate of childhood obesity has more than tripled in the past 30 years. The prevalence of obesity puts children at greater risk of developing heart disease, type 2 diabetes, stroke and other illnesses, and of suffering severe obesity as adults.

11 Apr 2012