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OncoEthix initiates OTX015 Phase I study in hematologic malignancies

OncoEthix, the Swiss-based specialist in oncology drug development, announces progress in its Phase I study of OTX015, a novel BET bromodomain inhibitor, with the first dosing of a patient.

31 Jan 2013

World Health Assembly's Executive Board concludes 132nd meeting

"The World Health Assembly's rotating Executive Board meets twice a year, and on 29 January concluded its 132nd meeting with what the WHO director general termed an 'unprecedented' amount of agenda items and documents," Intellectual Property Watch reports.

31 Jan 2013

Performing angiography and cardiac surgery on the same day increases risk of acute kidney injury

Performing heart surgery on the same day as angiography is now confirmed as a risk factor for acute kidney injury (AKI), and hospital policy limiting the practice for elective cardiac surgery has significantly reduced the rate of AKI, according to a study published in the February 2013 issue of The Annals of Thoracic Surgery.

31 Jan 2013

No added benefit from linagliptin in patients with type 2 diabetes

Linagliptin has been approved since August 2011 to improve blood glucose control in adults with type 2 diabetes. The assessment of the new dossier according to the German Act on the Reform of the Market for Medicinal Products (AMNOG) again showed that no added benefit of the drug over the appropriate comparator therapy (ACT) can be determined, because the pharmaceutical company has not submitted any relevant studies.

31 Jan 2013

UIC to determine whether exercise can shorten recovery time for stem cell transplant patients

Researchers at the University of Illinois at Chicago College of Nursing have received a four-year grant to determine whether exercise can shorten recovery time for patients who undergo high-dose chemotherapy and stem cell transplantation.

From Danaher 31 Jan 2013

Increasing age, male sex and adiposity risk factors for metabolic syndrome in children

Metabolic syndrome is more likely to affect children who are obese than overweight or non-overweight and who have other characteristics associated with the disorder, such as high blood pressure or insulin resistance. A new comprehensive and systematic review of the medical literature on metabolic syndrome in children that probed deeper to evaluate the risk associated with gender, ethnicity, and geography was published in Metabolic Syndrome and Related Disorders, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

31 Jan 2013

STS presents Earl Bakken Scientific Achievement Award to Stanford University professor

The Society of Thoracic Surgeons presented the Earl Bakken Scientific Achievement Award to D. Craig Miller, MD on Tuesday morning during the General Session at the STS 49th Annual Meeting.

31 Jan 2013

Pipeline embolization device safe and effective tool for patients with brain aneurysms

A multi-center study supports the effectiveness of the newest technology available for the treatment of difficult, life-threatening brain aneurysms. The technology, the Pipeline embolization device, is a flow diverter that redirects blood flow away from wide-necked or giant aneurysms that cannot be treated in more conventional ways.

31 Jan 2013

CKD may raise risk of mortality and end stage renal disease for both men and women

A new study from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium (CKD-PC) found that in general chronic kidney disease is similarly associated with a higher risk of death and end stage renal disease for both women and men. The findings were released online in advance of publication in BMJ.

31 Jan 2013

Genentech announces positive results from GA101 plus chlorambucil Phase III study on CLL

Genentech, a member of the Roche Group, today announced positive results from Stage 1 of CLL11, a Phase III randomized study to investigate the efficacy and safety profile of the investigational medicine obinutuzumab (GA101) plus chlorambucil chemotherapy compared with chlorambucil alone in people with previously untreated chronic lymphocytic leukemia (CLL).

31 Jan 2013

Binge drinking causes insulin resistance and increases risk of Type 2 diabetes

Binge drinking causes insulin resistance, which increases the risk of Type 2 diabetes, according to the results of an animal study led by researchers at the Diabetes Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai.

31 Jan 2013

Silibinin kills skin cells mutated by UVA radiation and protects against cancer

A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation - thus protecting against UV-induced skin cancer and photo-aging.

31 Jan 2013

Guidelines to help people with allergies during bad weather

As this winter continue to take many parts of the country on a temperature roller coaster ride—from seasonal bone-chilling cold to springlike warmth and then back again—many people find themselves reaching for pain relievers or other remedies to deal with runny noses and other symptoms associated with sinus and allergy problems.

31 Jan 2013

New noninvasive method for early detection of osteoarthritis may be on its way

A new, noninvasive, and low-cost method for the early detection and monitoring of osteoarthritis (arthritis caused by wear and tear) may be on its way, thanks to research by UC Santa Barbara scientists from the Department of Chemical Engineering and the Department of Materials.

31 Jan 2013

Retired Jackson Laboratory scientist wins two major international science awards

Douglas Coleman, Ph.D., a retired Jackson Laboratory scientist whose work established the first clues to a genetic component in obesity, has won two major international science awards: the Frontiers of Knowledge Award in Biomedicine from the BBVA Foundation, based in Bilbao, Spain, and the King Faisal International Prize in Medicine from the Saudi Arabian King Faisal Foundation.

31 Jan 2013

Existing cardiomyocytes contribute to formation of new heart cells after attack

Injecting specialized cardiac stem cells into a patient's heart rebuilds healthy tissue after a heart attack, but where do the new cells come from and how are they transformed into functional muscle?

31 Jan 2013

Interrupting key interaction between p68 and calcium-calmodulin inhibits cancer metastasis

Disrupting a key interaction between two types of proteins in cells inhibits the spread of cancerous cells, providing researchers with a new pathway toward developing cancer-fighting drugs, according to new findings by Georgia State University scientists.

31 Jan 2013

Possible new direction for treatment of metabolic syndrome

Obesity might be a very modern problem, but a team of scientists from Taiwan and China is turning to the age-old principles of traditional Chinese medicine (TCM) to help fight it. Breaking research published in the Journal of Biomolecular Structure and Dynamics indicates a possible new direction for the treatment of metabolic syndrome.

31 Jan 2013

Supplementation with omega-3 fatty acids promotes effective immune system response

Supplementation with omega-3 fatty acids promotes effective immune system response and has ameliorating effects on chronic inflammation (a condition caused by an imbalanced immune system that can lead to multiple serious illnesses over time), according to the most recent study published by the National Center for Biotechnology Information on the effects of omega-3.

31 Jan 2013

Medical Condition News

OncoEthix initiates OTX015 Phase I study in hematologic malignancies

World Health Assembly's Executive Board concludes 132nd meeting

Performing angiography and cardiac surgery on the same day increases risk of acute kidney injury

No added benefit from linagliptin in patients with type 2 diabetes

UIC to determine whether exercise can shorten recovery time for stem cell transplant patients

Increasing age, male sex and adiposity risk factors for metabolic syndrome in children

Review article highlights growing evidence for lasting impact of alcohol on the brain

STS presents Earl Bakken Scientific Achievement Award to Stanford University professor

Pipeline embolization device safe and effective tool for patients with brain aneurysms

CKD may raise risk of mortality and end stage renal disease for both men and women

Genentech announces positive results from GA101 plus chlorambucil Phase III study on CLL

Binge drinking causes insulin resistance and increases risk of Type 2 diabetes

Silibinin kills skin cells mutated by UVA radiation and protects against cancer

Guidelines to help people with allergies during bad weather

New noninvasive method for early detection of osteoarthritis may be on its way

Retired Jackson Laboratory scientist wins two major international science awards

Existing cardiomyocytes contribute to formation of new heart cells after attack

Interrupting key interaction between p68 and calcium-calmodulin inhibits cancer metastasis

Possible new direction for treatment of metabolic syndrome

Supplementation with omega-3 fatty acids promotes effective immune system response

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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