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FHCRC research represents potential breakthrough in treatment of pancreas cancer

Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor builds around itself. Now scientists at Fred Hutchinson Cancer Research Center have found a way to break through that defense, and their research represents a potential breakthrough in the treatment of pancreas cancer.

20 Mar 2012

Benvenue Medical initiates enrollment in Luna Interbody System for Fusion Trial

Benvenue Medical, Inc., a developer of minimally invasive solutions for spine repair, announced that it has actively started enrolling patients in the Luna Interbody System for Fusion Trial.

20 Mar 2012

Hedgehog and mTOR pathway are active in esophageal cancer

Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs that attack the Hedgehog pathway.

20 Mar 2012

AstraZeneca, Targacept announce top-line results from remaining TC-5214 Phase 3 studies on MDD

AstraZeneca and Targacept, Inc. today announced top-line results from the remaining Phase 3 studies investigating efficacy, tolerability and safety of TC-5214 as an adjunct therapy to an antidepressant in patients with major depressive disorder (MDD) who did not respond adequately to initial antidepressant treatment.

20 Mar 2012

New book on war trauma and its aftermath

A new book by a University of New Hampshire researcher and Vietnam-era disabled veteran sheds new light on the long-term psychological trauma experienced by the coalition force in recent wars in the Gulf and Balkans that, when left untreated, can have deadly consequences.

20 Mar 2012

AAFA releases new 'Spring Allergy Capital' rankings

Today is the vernal equinox – otherwise known as the official end of winter and the start of spring. But even if you didn't look at your calendar today, chances are your nose already figured it out. That's because more than 40 million Americans have nasal allergies.

20 Mar 2012

Heptares exercises exclusive option to license new A2A antagonist for CNS disorders

Heptares Therapeutics, the leading GPCR drug discovery company, announces that an operating company of Shire PLC, the global specialty biopharmaceutical company, has exercised its exclusive option to license a novel adenosine A2A antagonist discovered by Heptares that is currently in preclinical development.

20 Mar 2012

Circadian rhythms control production of metabolites

By analyzing the hundreds of metabolic products present in the liver, researchers with the UC Irvine Center for Epigenetics & Metabolism have discovered that circadian rhythms - our own body clock - greatly control the production of such key building blocks as amino acids, carbohydrates and lipids.

20 Mar 2012

Otolaryngology-Head and Neck Surgery publishes new sudden hearing loss guideline

The first national treatment guideline for sudden hearing loss, a frightening condition that sends thousands in the U.S. to the emergency room each year, was published this month in the journal Otolaryngology-Head and Neck Surgery.

20 Mar 2012

iPSYCH project to study five specific mental disorders

Is it possible to prevent the development of schizophrenia? Can certain patients develop autism if they carry a specific gene and have been exposed to a viral fetal infection? Should all ADHD patients take the same type of medication? This unique research project will try to answer these questions. The project is based at Aarhus University and will be known as 'The Lundbeck Foundation's Initiative for Integrative Psychiatric Research.'

20 Mar 2012

Peer mentor intervention improves glucose control in African American veterans with diabetes

by peer mentors has a statistically significant effect on improving glucose control in African American veterans with diabetes, according to a study by researchers at the Perelman School of Medicine at the University of Pennsylvania and the Philadelphia VA Center for Health Equity Research and Promotion.

20 Mar 2012

Styling practices linked with hair or scalp diseases among African Americans

Styling practices can lead to serious hair and scalp diseases for some African Americans, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.

20 Mar 2012

CJC publishes updated atrial fibrillation guidelines

The Canadian Journal of Cardiology has published a focused update to the Canadian Cardiovascular Society's atrial fibrillation guidelines.

20 Mar 2012

PATHS to examine needs of heart failure patients and primary caregivers

Less than 10 percent of people with heart failure receive supportive or palliative care beyond basic medical services, but a new research project, funded by a $1.7 million grant from the National Institute for Nursing Research to Penn State's School of Nursing, aims to change the situation.

20 Mar 2012

New information on efficacy of CLA in treating Crohn's disease

The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) research team at Virginia Tech has discovered important new information on the efficacy of conjugated linoleic acid (CLA) in treating Crohn's disease, a form of inflammatory bowel disease (IBD). CLA is a naturally occurring acid found in meat and dairy products known for its anti-cancer and immune modulatory properties.

20 Mar 2012

Epidemiologist examines effect of population aging on inpatient care

The effect of population aging on the number of admissions to hospital for inpatient treatment is examined by epidemiologist Enno Nowossadeck in the latest issue of Deutsches -rzteblatt International.

20 Mar 2012

Two Cedars-Sinai physicians to receive ACC Distinguished Scientist Award

Two physicians from the Cedars-Sinai Heart Institute will receive the American College of Cardiology's highest honors for scientific research and clinical care during the organization's upcoming annual scientific meeting in Chicago.

20 Mar 2012

Single dose of X-ray radiation can prevent glaucoma

Jackson Laboratory researchers have demonstrated that a single, targeted x-ray treatment of an individual eye in young, glaucoma-prone mice provided that eye with apparently life-long and typically complete protection from glaucoma.

20 Mar 2012

Researchers discover new method to identify cancer-causing translocations

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report they have discovered a method to identify cancer-causing rearrangements of genetic material called chromosomal translocations quickly, accurately, and inexpensively.

20 Mar 2012

Health must be taken into account in climate change mitigation strategies

Health must be taken into account in climate change mitigation strategies. It is not widely appreciated that there are many benefits to health that are likely to accrue from a low carbon economy, say experts in a special supplement published on bmj.com today.

20 Mar 2012