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Study reveals increase in incidence of dialysis-requiring acute kidney injury

Acute kidney injury (AKI), an abrupt or rapid decline in kidney function, is a serious and increasingly prevalent condition that can occur after major infections, major surgery, or exposure to certain medications.

7 Dec 2012

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Eileen White, PhD, associate director for basic science at The Cancer Institute of New Jersey and professor of molecular biology and biochemistry at Rutgers, The State University of New Jersey, and colleagues from Princeton University have been awarded a new five-year, $2.4 million dollar research grant from the National Cancer Institute.

7 Dec 2012

Study demonstrates how parasites enter the brain to influence its host

Toxoplasma is a common 'cat parasite', and has previously been in the spotlight owing to its observed effect on risk-taking and other human behaviours. To some extent, it has also been associated with mental illness. A study led by researchers from Karolinska Institutet in Sweden now demonstrates for the first time how the parasite enters the brain to influence its host.

7 Dec 2012

Scientists describe network map of genes involved in pain perception

Scientists in Australia and Austria have described a "network map" of genes involved in pain perception, with remarkable similarity from fruit flies to people. The work should help identify new analgesic drugs.

7 Dec 2012

Genomic sequencing reveals therapeutic drug targets for metastatic triple-negative breast cancer

Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) and US Oncology Research.

7 Dec 2012

Study identifies epigenetic events critical to cancer cell survival

USC Norris Comprehensive Cancer Center research that identifies specific genes that have to be turned off in order for cancer cells to survive was named one of the top major advances in cancer research this year by the American Society of Clinical Oncology (ASCO).

7 Dec 2012

Boston Scientific’s Precision Spectra Spinal Cord Stimulator System receives CE Mark approval

Boston Scientific Corporation has received CE Mark approval and has begun the European market launch of the Precision Spectra Spinal Cord Stimulator (SCS) System.

7 Dec 2012

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

There are two major forms of kidney cancer. One is called renal cell cancer, which is an adenocarcinoma that occurs in the renal parenchyma. The other major type is called renal pelvis cancer, which is mostly of transitional cell type and they form in the centre of the kidney where the urine collects.

7 Dec 2012

Disturbances in several immune-system-related pathways contribute to development of ASDs

Researchers using novel approaches and methodologies of identifying genes that contribute to the development of autism have found evidence that disturbances in several immune-system-related pathways contribute to development of autism spectrum disorders.

7 Dec 2012

New genetic process could provide novel target for treatment of neurodevelopmental disorders

Researchers at the Douglas Mental Health University Institute, have discovered a new genetic process that could one day provide a novel target for the treatment of neurodevelopmental disorders, such as intellectual disability and autism.

7 Dec 2012

JAACAP editorial addresses 'translation gap' in autism research

An editorial published in the November 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) discusses the challenge of translating scientific research in autism into clinical practice, and presents a series of studies published over several months that address this 'translation gap'.

7 Dec 2012

Study reveals dual role for Norrin/Frizzled-4 protein pair

Working with mice, Johns Hopkins researchers have shed light on the activity of a protein pair found in cells that form the walls of blood vessels in the brain and retina, experiments that could lead to therapeutic control of the blood-brain barrier and of blood vessel growth in the eye.

7 Dec 2012

New technique can reduce hemodialysis complications in kidney patients

Approximately two million people around the world regularly undergo hemodialysis - blood purification outside the body - as a result of kidney failure. This usually involves creating a dialysis fistula - a connection between an artery and a vein - in the patient's arm. However this causes complications in as many as 50% of patients, primarily related to changes in blood flow.

7 Dec 2012

General thoracic surgeons perform vast majority of complex noncardiac operations

While thoracic surgeons are traditionally known as the experts who perform heart surgeries, a UC Davis study has found that general thoracic surgeons, especially those at academic health centers, perform the vast majority of complex noncardiac operations, including surgeries of the esophagus and lungs.

7 Dec 2012

Gene therapy could represent new treatment option for severe orthopaedic injuries

Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities.

7 Dec 2012

Weekly telephone contact with nurses reduces hospital re-admissions for high-risk patients

Weekly telephone contact with a nurse substantially reduced hospital re-admissions for high-risk patients, according to results of a University of Wisconsin School of Medicine and Public Health (SMPH) study.

7 Dec 2012

Researchers discover 29 proteins associated with spread of kidney cancer

Researchers at St. Michael's hospital have identified 29 proteins that are likely to be involved in the spread of kidney cancer. The discovery will help physicians recognize which tumours are going to behave more aggressively and provide those patients with more intensive treatment and closer followup.

7 Dec 2012

Cocktail-treated human NK cells show promise against cancer

Fighting cancer using the body's own defense system is a promising treatment approach. Immune therapies have even become clinical routine in treating a few cancers such as malignant melanoma and prostate cancer. Natural killer cells (or NK cells) are considered to be particularly suitable weapons against cancer.

7 Dec 2012

University of Michigan to create National Kidney Disease Registry

The University of Michigan Kidney Epidemiology and Cost Center will create a National Kidney Disease Registry to monitor kidney disease among America's veterans.

7 Dec 2012

BDNF molecule appears to play a direct role in regulation of blood pressure

Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells during hypertension.

7 Dec 2012

Medical Condition News

Study reveals increase in incidence of dialysis-requiring acute kidney injury

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Study demonstrates how parasites enter the brain to influence its host

Scientists describe network map of genes involved in pain perception

Genomic sequencing reveals therapeutic drug targets for metastatic triple-negative breast cancer

Study identifies epigenetic events critical to cancer cell survival

Boston Scientific’s Precision Spectra Spinal Cord Stimulator System receives CE Mark approval

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

Disturbances in several immune-system-related pathways contribute to development of ASDs

New genetic process could provide novel target for treatment of neurodevelopmental disorders

JAACAP editorial addresses 'translation gap' in autism research

Study reveals dual role for Norrin/Frizzled-4 protein pair

New technique can reduce hemodialysis complications in kidney patients

General thoracic surgeons perform vast majority of complex noncardiac operations

Gene therapy could represent new treatment option for severe orthopaedic injuries

Weekly telephone contact with nurses reduces hospital re-admissions for high-risk patients

Researchers discover 29 proteins associated with spread of kidney cancer

Cocktail-treated human NK cells show promise against cancer

University of Michigan to create National Kidney Disease Registry

BDNF molecule appears to play a direct role in regulation of blood pressure

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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