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Statins improves progression-free survival in patients with inflammatory breast cancer

Researchers from The University of Texas MD Anderson Cancer Center found statins, the commonly used drug to lower cholesterol, improved progression-free survival in patients with inflammatory breast cancer (IBC).

6 Dec 2012

Study finds relationships between body size and epigenetic changes

New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by ageing but are also affected by what we eat.

6 Dec 2012

Children with snoring or apnea have concurrent behavioral sleep problems

Children with sleep-related breathing problems (such as snoring or apnea) frequently have concurrent behavioral sleep problems (such as waking repeatedly) - and vice versa, according to research led by a scientist at Albert Einstein College of Medicine of Yeshiva University.

6 Dec 2012

SOX2 directly regulated by tumor suppressor CDKN1B(p27) gene

A team of researchers from the Spanish National Cancer Research Centre (CNIO), led by Manuel Serrano, from the Tumour Suppression Group, together with scientists from London and Santiago de Compostela, has discovered that the cellular reprogramming gene SOX2, which is involved in several types of cancers, such as lung cancer and pituitary cancer, is directly regulated by the tumor suppressor CDKN1B(p27) gene, which is also associated with these types of cancer.

6 Dec 2012

Scientists identify novel mechanism by which ketogenic diet could delay effects of aging

Scientists at the Gladstone Institutes have identified a novel mechanism by which a type of low-carb, low-calorie diet-called a "ketogenic diet"-could delay the effects of aging. This fundamental discovery reveals how such a diet could slow the aging process and may one day allow scientists to better treat or prevent age-related diseases, including heart disease, Alzheimer's disease and many forms of cancer.

6 Dec 2012

All-day snacking might not be beneficial for obese women

Media articles and nutritionists alike have perpetuated the idea that for healthy metabolisms individuals should consume small meals multiple times a day. However, new research conducted at the University of Missouri suggests all-day snacking might not be as beneficial as previously thought, especially for obese women.

6 Dec 2012

Naurex reports positive results from GLYX-13 Phase IIa trial on depression

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today reported positive results from a Phase IIa clinical trial of its lead antidepressant compound, GLYX-13.

6 Dec 2012

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin.

6 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

Researchers unlock mechanisms of how the body converts dietary carbohydrates into fat

A gene that helps the body convert that big plate of holiday cookies you just polished off into fat could provide a new target for potential treatments for fatty liver disease, diabetes and obesity.

6 Dec 2012

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Bio-Path Holdings, Inc., a biotechnology company developing a liposomal delivery technology for nucleic acid cancer drugs, today announced it is initiating development of its lead cancer drug BP-100-1.01 (Liposomal Grb-2) to treat triple negative breast cancer (TNBC) and inflammatory breast cancer (IBC), two cancers characterized by formation of aggressive tumors and relatively high mortality rates.

6 Dec 2012

Study catalogs genetic variation of microbes that live in the gut

Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine.

6 Dec 2012

Electrotherapy not effective pain treatment in the aftermath of pancreatic surgery

Osteopathy may help reduce chronic pain and stiffness after thoracic surgery. However, electrotherapy is not effective pain treatment in the aftermath of pancreatic surgery. These are the findings of a thesis from Sahlgrenska Academy, University of Gothenburg, Sweden, that studied complementary and alternative therapies.

6 Dec 2012

Scancell announces preliminary results from Part 1 of ImmunoBody vaccine Phase 1/2 MM trial

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, is pleased to announce preliminary results from Part 1 of the Phase 1/2 clinical trial of its DNA ImmunoBody vaccine in patients with Stage III/IV malignant melanoma.

6 Dec 2012

UC San Diego Health System receives Comprehensive Stroke Center designation

UC San Diego Medical Center-Hillcrest is one of five facilities in the country, and the only center in San Diego County, to be recognized as one of the first Comprehensive Stroke Centers (CSC), the newest level of certification for advanced stroke care awarded by The Joint Commission.

6 Dec 2012

Galectins play an important role in development of osteoarthrosis

Inflammatory joint disease (arthritis) is affecting more and more, and especially older, people. In a recent survey by Statistik Austria, 39 per cent of people over the age of 60 stated that they have a form of arthritis. One particular form of the condition is osteoarthrosis, which is wear and tear on the joints.

6 Dec 2012

Few new doctors choose primary care

Less than a quarter of new doctors are choosing primary care as their specialty, even after finishing residency programs focused on internal medicine, a new study reports.

6 Dec 2012

North Shore-LIJ, VA open Unified Behavioral Health Center for Military Veterans and Their Families

Representatives from the US Department of Veterans Affairs (VA), the North Shore-LIJ Health System and local veterans today celebrated the opening of the Unified Behavioral Health Center for Military Veterans and Their Families, a first-of-its-kind facility designed to help military families cope with the emotional burdens veterans frequently face after returning home from combat.

6 Dec 2012

Using Nanoparticles to Target Cancer

An interview with John Stroh, discussing the development of nanoparticles that can target and treat cancer, without damaging nearby tissues.

6 Dec 2012

WHO establishes global monitoring framework for NCDs

"The World Health Organization (WHO) established a global monitoring framework for non-communicable diseases (NCDs) at a Geneva meeting on November 9, 2012 -- a little over a year after the U.N. General Assembly adopted a political declaration on NCDs," Management Sciences for Health's "Global Health Impact" blog reports, noting Ambassador Betty King, permanent representative of the U.S. to the U.N. and other international organizations in Geneva, announced the framework in November.

6 Dec 2012